2026 ICD-10-CM Diagnosis Code E72.548Other secondary hyperoxaluria

ICD-10-CM Codes›E00–E89›E70-E88›E72

ICD-10-CM E72.548
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E72.548 is a billable ICD-10-CM diagnosis code for other secondary hyperoxaluria. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 695 through 696. Coders also document this condition as antifreeze oxalosis.

Code Identity

ICD-10-CM Code
E72.548
Billable Status
Yes — Valid for Submission
Code Describes
Other secondary hyperoxaluria
Short Description
Other secondary hyperoxaluria
Same as the full description in the CMS dataset.
Parent Code
E72.54
Secondary hyperoxaluria

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE72Other disorders of amino-acid metabolism
This CodeE72.548Other secondary hyperoxaluria

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Antifreeze oxalosis
  • Secondary oxalosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • glycine metabolism
        • hyperoxaluria
          • secondary
            • specified type NEC

Code History & ChangesHistory

New Code E72.548 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement E72.548 replaces the following previously assigned code(s):

  • R82.992 - Hyperoxaluria
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About E72.548Overview

Is E72.548 (Secondary hyperoxaluria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other secondary hyperoxaluria on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E72.548 group to?

When other secondary hyperoxaluria is the principal diagnosis on an inpatient stay, it groups to MS-DRG 695, 696, with relative weights from 0.6890 to 1.1438 depending on complications. Higher weights mean higher Medicare reimbursement.