2026 ICD-10-CM Diagnosis Code E72.541Enteric hyperoxaluria

ICD-10-CM CodesE00–E89E70-E88E72

ICD-10-CM E72.541
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E72.541 is a billable ICD-10-CM diagnosis code for enteric hyperoxaluria. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 695 through 696.

Code Identity

ICD-10-CM Code
E72.541
Billable Status
Yes — Valid for Submission
Code Describes
Enteric hyperoxaluria
Short Description
Enteric hyperoxaluria
Same as the full description in the CMS dataset.
Parent Code
Secondary hyperoxaluria

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE72Other disorders of amino-acid metabolism
This CodeE72.541Enteric hyperoxaluria

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Enteric hyperoxaluria
  • Secondary oxalosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • glycine metabolism
        • hyperoxaluria
          • enteric

Clinical InformationClinical

  • Enteric Hyperoxaluria

    excessive urinary oxalate excretion resulting from increased absorption of oxalate.

Code History & ChangesHistory

New Code E72.541 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement E72.541 replaces the following previously assigned code(s):

  • R82.992 - Hyperoxaluria
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About E72.541Overview

Is E72.541 (Secondary hyperoxaluria) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report enteric hyperoxaluria on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E72.541 group to?

When enteric hyperoxaluria is the principal diagnosis on an inpatient stay, it groups to MS-DRG 695, 696, with relative weights from 0.6890 to 1.1438 depending on complications. Higher weights mean higher Medicare reimbursement.