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  3. Diagnosis Codes in MS-DRG 645 - Endocrine Disorders Without CC/MCC

Diagnosis Codes in MS-DRG 645 - Endocrine Disorders Without CC/MCC

The Medicare Severity Diagnosis-Related Group (MS-DRG) is a patient classification system used to categorize hospital cases based on clinical similarity and expected resource use. MS-DRGs organize all possible principal diagnoses into mutually exclusive groups known as Major Diagnostic Categories (MDCs), which help determine reimbursement under the Medicare Inpatient Prospective Payment System.

This section lists the diagnosis codes included in MS-DRG V43.0: Endocrine Disorders without CC/MCC from October 1, 2025, through September 30, 2026.

MS-DRG: 645

MS-DRG Title: Endocrine Disorders without CC/MCC

MCD: 10

Relative Weight: 0.7683 Relative Weight
The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Geometric LOS: 2.70 Geometric Length of Stay
The geometric mean length of stay (GMLOS) is used by Medicare to calculate the reimbursement for patients whose medical treatment takes a much longer or shorter time than average.

Arithmetic LOS: 3.20 Arithmetic Length of Stay
The average length of stay (ALOS) reflects the average number of days a patient spends in a hospital for each admission.

  1. A18 - Tuberculosis of other organs
  2. A18.8 - Tuberculosis of other specified organs
  3. B67.3 - Echinococcus granulosus infection, other and multipl
  4. C74.0 - Malignant neoplasm of cortex of adrenal gland
  5. C74.1 - Malignant neoplasm of medulla of adrenal gland
  6. C74.9 - Malignant neoplasm of unspecified part of adrenal gl
  7. C75 - Malignant neoplasm of other endocrine glands and relat
  8. C79.7 - Secondary malignant neoplasm of adrenal gland
  9. D13 - Benign neoplasm of other and ill-defined parts of dige
  10. D35 - Benign neoplasm of other and unspecified endocrine gla
  11. D35.0 - Benign neoplasm of adrenal gland
  12. D44 - Neoplasm of uncertain behavior of endocrine glands
  13. D44.1 - Neoplasm of uncertain behavior of adrenal gland
  14. D49 - Neoplasms of unspecified behavior
  15. E00 - Congenital iodine-deficiency syndrome
  16. E01 - Iodine-deficiency related thyroid disorders and allied
  17. E03 - Other hypothyroidism
  18. E04 - Other nontoxic goiter
  19. E05.0 - Thyrotoxicosis with diffuse goiter
  20. E05.1 - Thyrotoxicosis with toxic single thyroid nodule
  21. E05.2 - Thyrotoxicosis with toxic multinodular goiter
  22. E05.3 - Thyrotoxicosis from ectopic thyroid tissue
  23. E05.4 - Thyrotoxicosis factitia
  24. E05.8 - Other thyrotoxicosis
  25. E05.9 - Thyrotoxicosis, unspecified
  26. E06 - Thyroiditis
  27. E07 - Other disorders of thyroid
  28. E07.8 - Other specified disorders of thyroid
  29. E16 - Other disorders of pancreatic internal secretion
  30. E16.A - Hypoglycemia level
  31. E20 - Hypoparathyroidism
  32. E20.8 - Other hypoparathyroidism
  33. E20.81 - Hypoparathyroidism due to impaired parathyroid horm
  34. E21 - Hyperparathyroidism and other disorders of parathyroid
  35. E22 - Hyperfunction of pituitary gland
  36. E23 - Hypofunction and other disorders of the pituitary glan
  37. E24 - Cushing's syndrome
  38. E25 - Adrenogenital disorders
  39. E26 - Hyperaldosteronism
  40. E26.0 - Primary hyperaldosteronism
  41. E26.8 - Other hyperaldosteronism
  42. E27 - Other disorders of adrenal gland
  43. E27.4 - Other and unspecified adrenocortical insufficiency
  44. E29 - Testicular dysfunction
  45. E30 - Disorders of puberty, not elsewhere classified
  46. E31 - Polyglandular dysfunction
  47. E31.2 - Multiple endocrine neoplasia [MEN] syndromes
  48. E34 - Other endocrine disorders
  49. E34.0 - Carcinoid syndrome
  50. E34.3 - Short stature due to endocrine disorder
  51. E34.32 - Genetic causes of short stature
  52. E34.5 - Androgen insensitivity syndrome
  53. E89 - Postprocedural endocrine and metabolic complications a
  54. Q89 - Other congenital malformations, not elsewhere classifi
  55. R94 - Abnormal results of function studies
  56. S11.10 - Unspecified open wound of thyroid gland
  57. S11.11 - Laceration without foreign body of thyroid gland
  58. S11.12 - Laceration with foreign body of thyroid gland
  59. S11.13 - Puncture wound without foreign body of thyroid glan
  60. S11.14 - Puncture wound with foreign body of thyroid gland
  61. S11.15 - Open bite of thyroid gland
  62. S37.812 - Contusion of adrenal gland
  63. S37.813 - Laceration of adrenal gland
  64. S37.818 - Other injury of adrenal gland
  65. S37.819 - Unspecified injury of adrenal gland

  • -

    • C73 - Malignant neoplasm of thyroid gland

    • D34 - Benign neoplasm of thyroid gland

    • E02 - Subclinical iodine-deficiency hypothyroidism

    • E35 - Disorders of endocrine glands in diseases classified elsewhere

  • A18 - Tuberculosis of other organs

    • A18.7 - Tuberculosis of adrenal glands

  • A18.8 - Tuberculosis of other specified organs

    • A18.81 - Tuberculosis of thyroid gland

  • B67.3 - Echinococcus granulosus infection, other and multiple sites

    • B67.31 - Echinococcus granulosus infection, thyroid gland

  • C74.0 - Malignant neoplasm of cortex of adrenal gland

    • C74.00 - Malignant neoplasm of cortex of unspecified adrenal gland

    • C74.01 - Malignant neoplasm of cortex of right adrenal gland

    • C74.02 - Malignant neoplasm of cortex of left adrenal gland

  • C74.1 - Malignant neoplasm of medulla of adrenal gland

    • C74.10 - Malignant neoplasm of medulla of unspecified adrenal gland

    • C74.11 - Malignant neoplasm of medulla of right adrenal gland

    • C74.12 - Malignant neoplasm of medulla of left adrenal gland

  • C74.9 - Malignant neoplasm of unspecified part of adrenal gland

    • C74.90 - Malignant neoplasm of unspecified part of unspecified adrenal gland

    • C74.91 - Malignant neoplasm of unspecified part of right adrenal gland

    • C74.92 - Malignant neoplasm of unspecified part of left adrenal gland

  • C79.7 - Secondary malignant neoplasm of adrenal gland

    • C79.70 - Secondary malignant neoplasm of unspecified adrenal gland

    • C79.71 - Secondary malignant neoplasm of right adrenal gland

    • C79.72 - Secondary malignant neoplasm of left adrenal gland

  • D13 - Benign neoplasm of other and ill-defined parts of digestive system

    • D13.7 - Benign neoplasm of endocrine pancreas

  • D35 - Benign neoplasm of other and unspecified endocrine glands

    • D35.1 - Benign neoplasm of parathyroid gland

    • D35.2 - Benign neoplasm of pituitary gland

    • D35.3 - Benign neoplasm of craniopharyngeal duct

    • D35.7 - Benign neoplasm of other specified endocrine glands

    • D35.9 - Benign neoplasm of endocrine gland, unspecified

  • D35.0 - Benign neoplasm of adrenal gland

    • D35.00 - Benign neoplasm of unspecified adrenal gland

    • D35.01 - Benign neoplasm of right adrenal gland

    • D35.02 - Benign neoplasm of left adrenal gland

  • D44 - Neoplasm of uncertain behavior of endocrine glands

    • D44.0 - Neoplasm of uncertain behavior of thyroid gland

    • D44.2 - Neoplasm of uncertain behavior of parathyroid gland

    • D44.3 - Neoplasm of uncertain behavior of pituitary gland

    • D44.4 - Neoplasm of uncertain behavior of craniopharyngeal duct

    • D44.9 - Neoplasm of uncertain behavior of unspecified endocrine gland

  • D44.1 - Neoplasm of uncertain behavior of adrenal gland

    • D44.10 - Neoplasm of uncertain behavior of unspecified adrenal gland

    • D44.11 - Neoplasm of uncertain behavior of right adrenal gland

    • D44.12 - Neoplasm of uncertain behavior of left adrenal gland

  • D49 - Neoplasms of unspecified behavior

    • D49.7 - Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system

  • E00 - Congenital iodine-deficiency syndrome

    • E00.0 - Congenital iodine-deficiency syndrome, neurological type

    • E00.1 - Congenital iodine-deficiency syndrome, myxedematous type

    • E00.2 - Congenital iodine-deficiency syndrome, mixed type

    • E00.9 - Congenital iodine-deficiency syndrome, unspecified

  • E03 - Other hypothyroidism

    • E03.0 - Congenital hypothyroidism with diffuse goiter

    • E03.1 - Congenital hypothyroidism without goiter

    • E03.2 - Hypothyroidism due to medicaments and other exogenous substances

    • E03.3 - Postinfectious hypothyroidism

    • E03.4 - Atrophy of thyroid (acquired)

    • E03.8 - Other specified hypothyroidism

    • E03.9 - Hypothyroidism, unspecified

  • E04 - Other nontoxic goiter

    • E04.0 - Nontoxic diffuse goiter

    • E04.1 - Nontoxic single thyroid nodule

    • E04.2 - Nontoxic multinodular goiter

    • E04.8 - Other specified nontoxic goiter

    • E04.9 - Nontoxic goiter, unspecified

  • E05.0 - Thyrotoxicosis with diffuse goiter

    • E05.00 - Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm

    • E05.01 - Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

  • E05.1 - Thyrotoxicosis with toxic single thyroid nodule

    • E05.10 - Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm

    • E05.11 - Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm

  • E05.2 - Thyrotoxicosis with toxic multinodular goiter

    • E05.20 - Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm

    • E05.21 - Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm

  • E05.3 - Thyrotoxicosis from ectopic thyroid tissue

    • E05.30 - Thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis or storm

    • E05.31 - Thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis or storm

  • E05.4 - Thyrotoxicosis factitia

    • E05.40 - Thyrotoxicosis factitia without thyrotoxic crisis or storm

    • E05.41 - Thyrotoxicosis factitia with thyrotoxic crisis or storm

  • E05.8 - Other thyrotoxicosis

    • E05.80 - Other thyrotoxicosis without thyrotoxic crisis or storm

    • E05.81 - Other thyrotoxicosis with thyrotoxic crisis or storm

  • E05.9 - Thyrotoxicosis, unspecified

    • E05.90 - Thyrotoxicosis, unspecified without thyrotoxic crisis or storm

    • E05.91 - Thyrotoxicosis, unspecified with thyrotoxic crisis or storm

  • E06 - Thyroiditis

    • E06.0 - Acute thyroiditis

    • E06.1 - Subacute thyroiditis

    • E06.2 - Chronic thyroiditis with transient thyrotoxicosis

    • E06.3 - Autoimmune thyroiditis

    • E06.4 - Drug-induced thyroiditis

    • E06.5 - Other chronic thyroiditis

    • E06.9 - Thyroiditis, unspecified

  • E07 - Other disorders of thyroid

    • E07.0 - Hypersecretion of calcitonin

    • E07.1 - Dyshormogenetic goiter

    • E07.9 - Disorder of thyroid, unspecified

  • E07.8 - Other specified disorders of thyroid

    • E07.89 - Other specified disorders of thyroid

  • E16 - Other disorders of pancreatic internal secretion

    • E16.0 - Drug-induced hypoglycemia without coma

    • E16.1 - Other hypoglycemia

    • E16.3 - Increased secretion of glucagon

    • E16.8 - Other specified disorders of pancreatic internal secretion

    • E16.9 - Disorder of pancreatic internal secretion, unspecified

  • E16.A - Hypoglycemia level

    • E16.A1 - Hypoglycemia level 1

    • E16.A2 - Hypoglycemia level 2

    • E16.A3 - Hypoglycemia level 3

  • E20 - Hypoparathyroidism

    • E20.0 - Idiopathic hypoparathyroidism

    • E20.9 - Hypoparathyroidism, unspecified

  • E20.8 - Other hypoparathyroidism

    • E20.89 - Other specified hypoparathyroidism

  • E20.81 - Hypoparathyroidism due to impaired parathyroid hormone secretion

    • E20.810 - Autosomal dominant hypocalcemia

    • E20.811 - Secondary hypoparathyroidism in diseases classified elsewhere

    • E20.812 - Autoimmune hypoparathyroidism

    • E20.818 - Other specified hypoparathyroidism due to impaired parathyroid hormone secretion

    • E20.819 - Hypoparathyroidism due to impaired parathyroid hormone secretion, unspecified

  • E21 - Hyperparathyroidism and other disorders of parathyroid gland

    • E21.0 - Primary hyperparathyroidism

    • E21.1 - Secondary hyperparathyroidism, not elsewhere classified

    • E21.2 - Other hyperparathyroidism

    • E21.3 - Hyperparathyroidism, unspecified

    • E21.4 - Other specified disorders of parathyroid gland

    • E21.5 - Disorder of parathyroid gland, unspecified

  • E22 - Hyperfunction of pituitary gland

    • E22.0 - Acromegaly and pituitary gigantism

    • E22.1 - Hyperprolactinemia

    • E22.2 - Syndrome of inappropriate secretion of antidiuretic hormone

    • E22.8 - Other hyperfunction of pituitary gland

    • E22.9 - Hyperfunction of pituitary gland, unspecified

  • E23 - Hypofunction and other disorders of the pituitary gland

    • E23.0 - Hypopituitarism

    • E23.1 - Drug-induced hypopituitarism

    • E23.2 - Diabetes insipidus

    • E23.3 - Hypothalamic dysfunction, not elsewhere classified

    • E23.6 - Other disorders of pituitary gland

    • E23.7 - Disorder of pituitary gland, unspecified

  • E24 - Cushing's syndrome

    • E24.0 - Pituitary-dependent Cushing's disease

    • E24.1 - Nelson's syndrome

    • E24.2 - Drug-induced Cushing's syndrome

    • E24.3 - Ectopic ACTH syndrome

    • E24.4 - Alcohol-induced pseudo-Cushing's syndrome

    • E24.8 - Other Cushing's syndrome

    • E24.9 - Cushing's syndrome, unspecified

  • E25 - Adrenogenital disorders

    • E25.0 - Congenital adrenogenital disorders associated with enzyme deficiency

    • E25.8 - Other adrenogenital disorders

    • E25.9 - Adrenogenital disorder, unspecified

  • E26 - Hyperaldosteronism

    • E26.1 - Secondary hyperaldosteronism

    • E26.9 - Hyperaldosteronism, unspecified

  • E26.0 - Primary hyperaldosteronism

    • E26.01 - Conn's syndrome

    • E26.02 - Glucocorticoid-remediable aldosteronism

    • E26.09 - Other primary hyperaldosteronism

  • E26.8 - Other hyperaldosteronism

    • E26.81 - Bartter's syndrome

    • E26.89 - Other hyperaldosteronism

  • E27 - Other disorders of adrenal gland

    • E27.0 - Other adrenocortical overactivity

    • E27.1 - Primary adrenocortical insufficiency

    • E27.2 - Addisonian crisis

    • E27.3 - Drug-induced adrenocortical insufficiency

    • E27.5 - Adrenomedullary hyperfunction

    • E27.8 - Other specified disorders of adrenal gland

    • E27.9 - Disorder of adrenal gland, unspecified

  • E27.4 - Other and unspecified adrenocortical insufficiency

    • E27.40 - Unspecified adrenocortical insufficiency

    • E27.49 - Other adrenocortical insufficiency

  • E29 - Testicular dysfunction

    • E29.0 - Testicular hyperfunction

    • E29.1 - Testicular hypofunction

    • E29.8 - Other testicular dysfunction

    • E29.9 - Testicular dysfunction, unspecified

  • E30 - Disorders of puberty, not elsewhere classified

    • E30.0 - Delayed puberty

    • E30.1 - Precocious puberty

    • E30.8 - Other disorders of puberty

    • E30.9 - Disorder of puberty, unspecified

  • E31 - Polyglandular dysfunction

    • E31.0 - Autoimmune polyglandular failure

    • E31.1 - Polyglandular hyperfunction

    • E31.8 - Other polyglandular dysfunction

    • E31.9 - Polyglandular dysfunction, unspecified

  • E31.2 - Multiple endocrine neoplasia [MEN] syndromes

    • E31.20 - Multiple endocrine neoplasia [MEN] syndrome, unspecified

    • E31.21 - Multiple endocrine neoplasia [MEN] type I

    • E31.22 - Multiple endocrine neoplasia [MEN] type IIA

    • E31.23 - Multiple endocrine neoplasia [MEN] type IIB

  • E34 - Other endocrine disorders

    • E34.1 - Other hypersecretion of intestinal hormones

    • E34.2 - Ectopic hormone secretion, not elsewhere classified

    • E34.4 - Constitutional tall stature

    • E34.8 - Other specified endocrine disorders

    • E34.9 - Endocrine disorder, unspecified

  • E34.0 - Carcinoid syndrome

    • E34.00 - Carcinoid syndrome, unspecified

    • E34.01 - Carcinoid heart syndrome

    • E34.09 - Other carcinoid syndrome

  • E34.3 - Short stature due to endocrine disorder

    • E34.30 - Short stature due to endocrine disorder, unspecified

    • E34.31 - Constitutional short stature

    • E34.39 - Other short stature due to endocrine disorder

  • E34.32 - Genetic causes of short stature

    • E34.321 - Primary insulin-like growth factor-1 (IGF-1) deficiency

    • E34.322 - Insulin-like growth factor-1 (IGF-1) resistance

    • E34.328 - Other genetic causes of short stature

    • E34.329 - Unspecified genetic causes of short stature

  • E34.5 - Androgen insensitivity syndrome

    • E34.50 - Androgen insensitivity syndrome, unspecified

    • E34.51 - Complete androgen insensitivity syndrome

    • E34.52 - Partial androgen insensitivity syndrome

  • E89 - Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified

    • E89.0 - Postprocedural hypothyroidism

    • E89.2 - Postprocedural hypoparathyroidism

    • E89.3 - Postprocedural hypopituitarism

    • E89.5 - Postprocedural testicular hypofunction

    • E89.6 - Postprocedural adrenocortical (-medullary) hypofunction

  • Q89 - Other congenital malformations, not elsewhere classified

    • Q89.1 - Congenital malformations of adrenal gland

    • Q89.2 - Congenital malformations of other endocrine glands

  • R94 - Abnormal results of function studies

    • R94.6 - Abnormal results of thyroid function studies

    • R94.7 - Abnormal results of other endocrine function studies

  • S11.10 - Unspecified open wound of thyroid gland

    • S11.10XA - Unspecified open wound of thyroid gland, initial encounter

  • S11.11 - Laceration without foreign body of thyroid gland

    • S11.11XA - Laceration without foreign body of thyroid gland, initial encounter

  • S11.12 - Laceration with foreign body of thyroid gland

    • S11.12XA - Laceration with foreign body of thyroid gland, initial encounter

  • S11.13 - Puncture wound without foreign body of thyroid gland

    • S11.13XA - Puncture wound without foreign body of thyroid gland, initial encounter

  • S11.14 - Puncture wound with foreign body of thyroid gland

    • S11.14XA - Puncture wound with foreign body of thyroid gland, initial encounter

  • S11.15 - Open bite of thyroid gland

    • S11.15XA - Open bite of thyroid gland, initial encounter

  • S37.812 - Contusion of adrenal gland

    • S37.812A - Contusion of adrenal gland, initial encounter

  • S37.813 - Laceration of adrenal gland

    • S37.813A - Laceration of adrenal gland, initial encounter

  • S37.818 - Other injury of adrenal gland

    • S37.818A - Other injury of adrenal gland, initial encounter

  • S37.819 - Unspecified injury of adrenal gland

    • S37.819A - Unspecified injury of adrenal gland, initial encounter