2026 ICD-10-CM Diagnosis Code D37.6Neoplasm of uncertain behavior of liver, gallbladder and bile ducts

ICD-10-CM CodesC00–D49D37-D48D37

ICD-10-CM D37.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D37.6 is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of liver, gallbladder and bile ducts. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 435 through 437. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D37.6
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of uncertain behavior of liver, gallbladder and bile ducts
Short Description
Neoplasm of uncertain behavior of liver, GB & bile duct
Parent Code
Neoplasm of uncertain behavior of oral cavity and digestive organs

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD37Neoplasm of uncertain behavior of oral cavity and digestive organs
This CodeD37.6Neoplasm of uncertain behavior of liver, gallbladder and bile ducts

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hemangioblastoma of liver
  • Hemangioendothelioma
  • Hemangioendothelioma of abdomen
  • Hemangioendothelioma of liver
  • Neoplasm of cystic duct
  • Neoplasm of uncertain behavior of ampulla of Vater
  • Neoplasm of uncertain behavior of bile duct
  • Neoplasm of uncertain behavior of biliary system
  • Neoplasm of uncertain behavior of common bile duct
  • Neoplasm of uncertain behavior of cystic duct
  • Neoplasm of uncertain behavior of duodenum
  • Neoplasm of uncertain behavior of extrahepatic bile ducts
  • Neoplasm of uncertain behavior of gallbladder
  • Neoplasm of uncertain behavior of hepatic duct
  • Neoplasm of uncertain behavior of intrahepatic bile ducts
  • Neoplasm of uncertain behavior of liver
  • Neoplasm of uncertain behavior of liver and/or biliary passages
  • Neoplasm of uncertain behavior of pancreas
  • Neoplasm of uncertain behavior of pancreatic duct
  • Neoplasm of uncertain behavior of small intestine
  • Neoplasm of uncertain behavior of smooth muscle
  • Neoplasm of uncertain behavior of sphincter of Oddi
  • Papillary tumor of ampulla of Vater

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Neoplasm of uncertain behavior of ampulla of Vater

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Ampulla of Vater

    a dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct, also known as the hepatopancreatic ampulla.
  • Acalculous Cholecystitis

    inflammation of the gallbladder wall in the absence of gallstones.
  • Biliary Dyskinesia

    a motility disorder characterized by biliary colic, absence of gallstones, and an abnormal gallbladder ejection fraction. it is caused by gallbladder dyskinesia and/or sphincter of oddi dysfunction.
  • Cholecystitis

    inflammation of the gallbladder; generally caused by impairment of bile flow, gallstones in the biliary tract, infections, or other diseases.
  • Gallbladder

    a storage reservoir for bile secretion. gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the cystic duct to the duodenum, for degradation of dietary lipid.
  • Gallbladder Diseases

    diseases of the gallbladder. they generally involve the impairment of bile flow, gallstones in the biliary tract, infections, neoplasms, or other diseases.
  • Gallbladder Emptying

    a process whereby bile is delivered from the gallbladder into the duodenum. the emptying is caused by both contraction of the gallbladder and relaxation of the sphincter mechanism at the choledochal terminus.
  • Gallbladder Neoplasms

    tumors or cancer of the gallbladder.
  • Hep G2 Cells

    a human liver tumor cell line used to study a variety of liver-specific metabolic functions.
  • Hepatoblastoma

    a malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (stedman, 25th ed)
  • Hemangioendothelioma

    a neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). they affect men and women about equally and rarely develop in childhood. (from stedman, 25th ed; holland et al., cancer medicine, 3d ed, p1866)
  • Hemangioendothelioma, Epithelioid

    a tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. these tumors are thought to have borderline aggression, where one-third develop local recurrences, but only rarely metastasize. it is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to kimura's disease (see angiolymphoid hyperplasia with eosinophilia). (segen, dictionary of modern medicine, 1992)
  • Angiolymphoid Hyperplasia with Eosinophilia

    solitary or multiple benign cutaneous nodules comprised of immature and mature vascular structures intermingled with endothelial cells and a varied infiltrate of eosinophils, histiocytes, lymphocytes, and mast cells.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
ampulla of VaterC24.1C78.89D01.5D13.5D37.6D49.0
bile or biliary (tract)C24.9C78.89D01.5D13.5D37.6D49.0
bile or biliary (tract) canaliculi (biliferi) (intrahepatic)C22.1C78.7D01.5D13.4D37.6D49.0
bile or biliary (tract) canals, interlobularC22.1C78.89D01.5D13.4D37.6D49.0
bile or biliary (tract) duct or passage (common) (cystic) (extrahepatic)C24.0C78.89D01.5D13.5D37.6D49.0
bile or biliary (tract) duct or passage (common) (cystic) (extrahepatic) interlobularC22.1C78.89D01.5D13.4D37.6D49.0
bile or biliary (tract) duct or passage (common) (cystic) (extrahepatic) intrahepaticC22.1C78.7D01.5D13.4D37.6D49.0
bile or biliary (tract) duct or passage (common) (cystic) (extrahepatic) intrahepatic and extrahepaticC24.8C78.89D01.5D13.5D37.6D49.0
canaliculi, biliary (biliferi) (intrahepatic)C22.1C78.7D01.5D13.4D37.6D49.0
cholangioleC22.1C78.89D01.5D13.4D37.6D49.0
choledochal ductC24.0C78.89D01.5D13.5D37.6D49.0
common (bile) ductC24.0C78.89D01.5D13.5D37.6D49.0
cystic (bile) duct (common)C24.0C78.89D01.5D13.5D37.6D49.0
extrahepatic (bile) ductC24.0C78.89D01.5D13.5D37.6D49.0
gall duct (extrahepatic)C24.0C78.89D01.5D13.5D37.6D49.0
gall duct (extrahepatic) intrahepaticC22.1C78.7D01.5D13.4D37.6D49.0
gallbladderC23C78.89D01.5D13.5D37.6D49.0
hepatic [See Also: Index to disease, by histology]C22.9C78.7D01.5D13.4D37.6D49.0
hepatic [See Also: Index to disease, by histology] duct (bile)C24.0C78.89D01.5D13.5D37.6D49.0
hepatic [See Also: Index to disease, by histology] primaryC22.8C78.7D01.5D13.4D37.6D49.0
hepatobiliaryC24.9C78.89D01.5D13.5D37.6D49.0
hepatoblastomaC22.2C78.7D01.5D13.4D37.6D49.0
hepatomaC22.0C78.7D01.5D13.4D37.6D49.0
intrahepatic (bile) ductC22.1C78.7D01.5D13.4D37.6D49.0
liver [See Also: Index to disease, by histology]C22.9C78.7D01.5D13.4D37.6D49.0
liver [See Also: Index to disease, by histology] primaryC22.8C78.7D01.5D13.4D37.6D49.0
sphincter of OddiC24.0C78.89D01.5D13.5D37.6D49.0
Vater's ampullaC24.1C78.89D01.5D13.5D37.6D49.0

Patient EducationClinical

Bile Duct Diseases

Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D37.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
235.3 Unc behav neo liver
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D37.6Overview

Is D37.6 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of uncertain behavior of liver, gallbladder and bile ducts on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D37.6 group to?

When neoplasm of uncertain behavior of liver, gallbladder and bile ducts is the principal diagnosis on an inpatient stay, it groups to MS-DRG 435, 436, 437, with relative weights from 0.8533 to 1.8367 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D37.6?

Under the General Equivalence Mappings, neoplasm of uncertain behavior of liver, gallbladder and bile ducts converts to ICD-9-CM 235.3 (unc behav neo liver). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.