MS-DRG 435 – Malignancy of Hepatobiliary System or Pancreas with MCC
A Medical DRG in MDC 07 (Diseases & Disorders of the Hepatobiliary System & Pancreas). Inpatient cases group to DRG 435 when the ICD-10-CM principal diagnosis is one of the 25 codes listed below and a secondary diagnosis on the major complication or comorbidity (MCC) list is present. Its FY 2026 relative weight is 1.8367 with a geometric mean length of stay of 4.8 days.
Severity family
The grouper first assigns the case to MDC 07 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 435; with CC → 436; without CC/MCC → 437.
Principal Diagnosis Codes 25 codes · 8 categories
C22 Malignant neoplasm of liver and intrahepatic bile ducts8 codes
- C22.0 Liver cell carcinoma
- C22.1 Intrahepatic bile duct carcinoma
- C22.2 Hepatoblastoma
- C22.3 Angiosarcoma of liver
- C22.4 Other sarcomas of liver
- C22.7 Other specified carcinomas of liver
- C22.8 Malignant neoplasm of liver, primary, unspecified as to type
- C22.9 Malignant neoplasm of liver, not specified as primary or secondary
C23 Malignant neoplasm of gallbladder1 code
- C23 Malignant neoplasm of gallbladder
C24 Malignant neoplasm of other and unspecified parts of biliary tract4 codes
C25 Malignant neoplasm of pancreas8 codes
- C25.0 Malignant neoplasm of head of pancreas
- C25.1 Malignant neoplasm of body of pancreas
- C25.2 Malignant neoplasm of tail of pancreas
- C25.3 Malignant neoplasm of pancreatic duct
- C25.4 Malignant neoplasm of endocrine pancreas
- C25.7 Malignant neoplasm of other parts of pancreas
- C25.8 Malignant neoplasm of overlapping sites of pancreas
- C25.9 Malignant neoplasm of pancreas, unspecified
C78 Secondary malignant neoplasm of respiratory and digestive organs1 code
- C78.7 Secondary malignant neoplasm of liver and intrahepatic bile duct
C7B Secondary neuroendocrine tumors1 code
- C7B.02 Secondary carcinoid tumors of liver
D01 Carcinoma in situ of other and unspecified digestive organs1 code
- D01.5 Carcinoma in situ of liver, gallbladder and bile ducts
D37 Neoplasm of uncertain behavior of oral cavity and digestive organs1 code
- D37.6 Neoplasm of uncertain behavior of liver, gallbladder and bile ducts
Procedure Codes
Frequently Asked Questions
What is MS-DRG 435?
MS-DRG 435 (Malignancy of Hepatobiliary System or Pancreas with MCC) is a medical DRG in MDC 07 (Diseases & Disorders of the Hepatobiliary System & Pancreas). Its FY 2026 relative weight is 1.8367 with a geometric mean length of stay of 4.8 days.
What is the difference between DRG 435, 436, 437?
All 3 share the same base category; the severity of secondary diagnoses separates them: 435 (with MCC), 436 (with CC), 437 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.
How many diagnosis codes group to DRG 435?
25 ICD-10-CM principal diagnosis codes group to this DRG, spanning 8 three-character categories.
What is the relative weight of DRG 435?
The FY 2026 relative weight of this DRG is 1.8367, meaning reimbursement of roughly 1.84 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.
