2026 ICD-10-CM Diagnosis Code Q78.8Other specified osteochondrodysplasias

ICD-10-CM Codes›Q00-Q99›Q65-Q79›Q78

ICD-10-CM Q78.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q78.8 is a billable ICD-10-CM diagnosis code for other specified osteochondrodysplasias. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Musculoskeletal congenital conditions.

Code Identity

ICD-10-CM Code
Q78.8
Billable Status
Yes — Valid for Submission
Code Describes
Other specified osteochondrodysplasias
Short Description
Other specified osteochondrodysplasias
Same as the full description in the CMS dataset.
Parent Code
Q78
Other osteochondrodysplasias

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ65-Q79Congenital malformations and deformations of the musculoskeletal system
CategoryQ78Other osteochondrodysplasias
This CodeQ78.8Other specified osteochondrodysplasias

Present on Admission (POA)Billing

Q78.8 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acrocapitofemoral dysplasia
  • Acrodysostosis
  • Acromesomelic dysplasia Hunter-Thompson type
  • Acromesomelic dysplasia Maroteaux type
  • Acroosteolysis
  • Acropectorovertebral dysplasia
  • Agenesis of fibula
  • Aluminum bone disease
  • Aluminum-related fracturing osteodystrophy
  • Angel-shaped phalangoepiphyseal dysplasia
  • Aplasia of fibula
  • Atelosteogenesis
  • Atelosteogenesis type 1
  • Atelosteogenesis type 2
  • Atelosteogenesis type 3
  • Autosomal dominant omodysplasia
  • Autosomal recessive omodysplasia
  • Beals auriculo-osteodysplasia syndrome
  • Benign osteogenic neoplasm of bone of limb
  • Bent bone dysplasia group
  • Blomstrand dysplasia
  • Body height below reference range
  • Bone dysplasia lethal Holmgren type
  • Boomerang dysplasia
  • Bowing of upper limb
  • Bruck syndrome
  • Carpal-tarsal osteolysis with nephropathy
  • Carpotarsal osteochondromatosis
  • Cerebral degeneration in childhood
  • Chitty Hall Baraitser syndrome
  • Chronic deafness
  • CHST3-related skeletal dysplasia
  • Cleidorhizomelic syndrome
  • Cole-Carpenter dysplasia
  • Colobomatous microphthalmia, rhizomelic dysplasia syndrome
  • Complex lethal osteochondrodysplasia
  • Congenital abnormal fusion of humerus
  • Congenital abnormal shape of humerus
  • Congenital abnormal shape of radius
  • Congenital absence of pectoral muscle
  • Congenital anomalies of elbow and upper arm
  • Congenital dysplasia of radius
  • Congenital exostosis
  • Congenital hypoplasia of bone of radius and/or ulna
  • Congenital hypoplasia of fibula
  • Congenital hypoplasia of tibia
  • Congenital hypoplasia of ulna
  • Congenital progressive bone marrow failure, B-cell immunodeficiency, skeletal dysplasia syndrome
  • Craniofrontonasal dysplasia with Poland anomaly syndrome
  • Craniometadiaphyseal dysplasia
  • Craniometadiaphyseal dysplasia wormian bone type
  • Craniometaphyseal dysplasia
  • Dacryocystitis and osteopoikilosis syndrome
  • Dappled diaphyseal dysplasia
  • Deafness, genital anomaly, metacarpal and metatarsal synostosis syndrome
  • Deformity of radius
  • Dermatofibrosis lenticularis disseminata
  • Desbuquois syndrome
  • Diaphanospondylodysostosis
  • Disorganized development of cartilaginous and fibrous components of the skeleton
  • Disproportionate short stature
  • Disuse osteodystrophy
  • Dysosteosclerosis
  • Dysostosis
  • Dysplasia with defective mineralization
  • Dysplasia with increased bone density
  • Dysplasias with significant membranous bone involvement
  • Dysplastic cortical hyperostosis
  • Dysplastic cortical hyperostosis Al-Gazali type
  • Dysplastic cortical hyperostosis Kozlowski Tsuruta type
  • Early-onset calcifying leukoencephalopathy, skeletal dysplasia
  • Enchondromatosis
  • Endocrine-cerebro-osteodysplasia syndrome
  • Endosteal hyperostoses
  • Endosteal hyperostoses with cerebellar hypoplasia
  • Epilepsy, microcephaly, skeletal dysplasia syndrome
  • Epileptic encephalopathy
  • Epiphyseal dysplasia
  • Epiphyseal dysplasia, hearing loss, dysmorphism syndrome
  • Epiphyseal dysplasia, microcephalus, nystagmus syndrome
  • Familial osteodysplasia Anderson type
  • FGFR2-related bent bone dysplasia
  • Fibrochondrogenesis
  • Frontometaphyseal dysplasia
  • Frontonasal dysplasia sequence
  • Geleophysic dysplasia
  • Genochondromatosis
  • Genochondromatosis type 1
  • Genochondromatosis type 2
  • Giacci familial neurogenic acroosteolysis
  • Gnathodiaphyseal dysplasia
  • Grant syndrome
  • Hair discoloration
  • Hajdu-Cheney syndrome
  • Hepatic osteodystrophy
  • Hereditary acroosteolysis
  • Humeroulnar synostosis
  • Hyperphosphatasemia tarda
  • Idiopathic hypoparathyroidism
  • Idiopathic osteolyses
  • Immuno-osseous dysplasia
  • Infantile cortical hyperostosis
  • Isolated osteopoikilosis
  • Kenny syndrome
  • Kniest dysplasia
  • Kniest-Stickler dysplasia
  • Kyphomelic dysplasia
  • Larsen-like osseous dysplasia, short stature syndrome
  • Larsen-like syndrome B3GAT3 type
  • Lenz-Majewski hyperostosis syndrome
  • Leri's pleonosteosis syndrome
  • Lethal chondrodysplasia with fragmented bone
  • Lethal congenital disproportionate short limbed short stature
  • Lethal Kniest-like syndrome
  • Lethal occipital encephalocele, skeletal dysplasia syndrome
  • Lethal recessive chondrodysplasia
  • Leukoencephalopathy with metaphyseal chondrodysplasia syndrome
  • Longitudinal deficiency of foot
  • LRP5-related primary osteoporosis
  • Melhem Fahl syndrome
  • Melnick-Needles syndrome
  • Melorheostosis with osteopoikilosis
  • Mesomelic dysplasia
  • Mesomelic dysplasia Kantaputra type
  • Mesomelic dysplasia of upper limb
  • Mesomelic dysplasia Savarirayan type
  • Mesomelic dysplasia, digital anomalies, intellectual disability syndrome
  • Metachondromatosis
  • Metaphyseal anadysplasia
  • Metaphyseal chondrodysplasia Kaitila type
  • Metatropic dysplasia
  • Microcephalic osteodysplastic dysplasia Saul Wilson type
  • Microcephalic osteodysplastic primordial dwarfism type II
  • Microcephalic osteodysplastic primordial dwarfism types I and III
  • Mixed sclerosing bone dysplasia
  • Mixed sclerosing bone dystrophy with extra-skeletal manifestation
  • Multiple dislocations with dysplasia
  • Multiple epiphyseal dysplasia
  • Multiple epiphyseal dysplasia due to collagen 9 anomaly
  • Multiple epiphyseal dysplasia Lowry type
  • Multiple epiphyseal dysplasia type 1
  • Multiple epiphyseal dysplasia type 4
  • Multiple epiphyseal dysplasia type 5
  • Multiple epiphyseal dysplasia type 7
  • Multiple epiphyseal dysplasia with miniepiphyses
  • Multiple epiphyseal dysplasia with severe proximal femoral dysplasia
  • Multiple synostosis syndrome
  • Myelodysplastic syndrome with low blasts
  • NEK9-related lethal skeletal dysplasia
  • Neonatal osteosclerotic dysplasia
  • Occipital encephalocele
  • Omodysplasia
  • Osteocraniostenosis
  • Osteodysplastic dysplasia, type I
  • Osteodysplastic dysplasia, type II
  • Osteodysplastic primordial dwarfism
  • Osteofibrous dysplasia
  • Osteoglophonic dysplasia
  • Osteopathia striata
  • Osteopathia striata, pigmentary dermopathy, white forelock syndrome
  • Osteoplastic dysplasia
  • Osteopoikilosis
  • Otopalatodigital syndrome spectrum disorder
  • Pachydermoperiostosis - familial
  • Pacman dysplasia
  • Poland anomaly
  • Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
  • Precocious osteodysplasty
  • Progressive pseudorheumatoid dysplasia
  • Pseudodiastrophic dysplasia
  • Pyknoachondrogenesis
  • Pyknodysostosis
  • QRICH1-related intellectual disability, chondrodysplasia syndrome
  • Raine dysplasia
  • Reardon Hall Slaney syndrome
  • Reinhardt Pfeiffer mesomelic dysplasia
  • Rhizomelic dysplasia Patterson Lowry type
  • Rhizomelic syndrome Urbach type
  • RHYNS syndrome
  • Rolland-Debuqois syndrome
  • Schimke immuno-osseous dysplasia
  • Sclerosteosis
  • Short stature, skeletal dysplasia, retinal degeneration, intellectual disability, sensorineural hearing loss syndrome
  • SHOX-related short stature
  • Skeletal dysplasia with epilepsy and short stature syndrome
  • Skeletal dysplasia, T-cell immunodeficiency, developmental delay syndrome
  • Smith McCort dysplasia
  • Spondylocarpotarsal synostosis syndrome
  • Spondylodysplasia, Luton type
  • Spondylodysplasia, San Diego type
  • Spondylodysplasia, Torrance type
  • Spondylodysplastic group
  • Spondyloenchondrodysplasia
  • Spondyloenchondrodysplasia with immune dysregulation
  • Spondyloepimetaphyseal dysplasia, Strudwick type
  • Spondyloepiphyseal dysplasia with congenital joint dislocations
  • Spondylometaphyseal dysplasia Schmidt type
  • Spondylometaphyseal dysplasia with cone-rod dystrophy syndrome
  • Spondylo-ocular syndrome
  • Stenosis of lacrimal canaliculi
  • Stuve-Wiedemann dysplasia
  • Syndromic nanophthalmos due to Kenny-Caffey syndrome
  • Terminal osseous dysplasia and pigmentary defect syndrome
  • Variation in hair color
  • Velofacioskeletal syndrome
  • Weismann Netter syndrome
  • White forelock
  • Whyte Hemingway carpal tarsal phalangeal osteolyses
  • X-linked calvarial hyperostosis
  • X-linked dominant chondrodysplasia Chassaing Lacombe type
  • X-linked osteoporosis with fractures
  • Yunis-Varon dysplasia

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Osteopoikilosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abnormal, abnormality, abnormalities
      • synchondrosis
    • Caffey's syndrome
    • Chondrodysplasia
      • metaphyseal (Jansen's) (McKusick's) (Schmid's)
    • Deficiency, deficient
      • short stature homeobox gene (SHOX)
        • with
          • dyschondrosteosis
    • Dysplasia
      • craniometaphyseal
    • Hypoplasia, hypoplastic
      • cartilage hair
    • Leri's pleonosteosis
    • Osteochondrodysplasia
      • specified NEC
    • Osteopathia condensans disseminata
    • Osteopoikilosis
    • Segmentation, incomplete(congenital)
      • bone NEC
    • Stippled epiphyses
    • Synchondrosis
      • abnormal (congenital)
    • Synostosis(congenital)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MAL008
Musculoskeletal congenital conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Enchondromatosis

    benign growths of cartilage in the metaphyses of several bones.

  • Osteopoikilosis

    an asymptomatic, autosomal dominant trait in which pea-sized sclerotic spots, prominent in the metaphyseal area, are accompanied by unique cutaneous lesions. these are yellowish papules or plaques with increased elastin content. (from cecil textbook of medicine, 19th ed, pp1434-35)

  • Acrofacial Dysostosis

    a group of rare genetic syndromes characterized by craniofacial and limb defects.

  • Spondylocostal Dysostosis

    a rare disorder caused by mutations in the dll3, mesp2, fng, or hes7 gene and characterized by abnormal development of bones in the spine and ribs.

  • Acrodysostosis 1|ACRDYS1

    an autosomal dominant skeletal dysplasia caused by mutation(s) in the prkar1a gene, encoding camp-dependent protein kinase type i-alpha regulatory subunit. it is characterized by short stature, brachydactyly, and characteristic facial features. resistance to multiple hormones is a common finding.

  • Cleidocranial Dysplasia|Cleidocranial Dysostosis|Cleidocranial Dysostosis

    a rare autosomal dominant disorder caused by mutations in the runx2 gene. it is characterized by developmental abnormalities in the bones and teeth, including the complete or partial absence of the clavicles, delayed closure of the fontanels, protruding mandible, hypertelorism, scoliosis, and short stature.

  • Craniofacial Dysostosis|Crouzon Syndrome|Crouzon Syndrome

    a syndrome inherited in an autosomal dominant pattern. it is characterized by early fusion of the bones of the skull and face. patients have a distinctive facial appearance which includes low-set ears, brachycephaly, hypertelorism, exophthalmos, and mandibular prognathism.

  • CTSK wt Allele|CTS02|CTSO|CTSO1|CTSO2|Cathepsin K (Pycnodysostosis) Gene|Cathepsin K wt Allele|Cathepsin O1 Gene|MGC23107|PKND|PYCD

    human ctsk wild-type allele is located in the vicinity of 1q21 and is approximately 12 kb in length. this allele, which encodes cathepsin k protein, plays a role in the regulation of both proteolysis and osteoclastic bone resorption. mutation of the gene is associated with pycnodysostosis.

  • Dysostosis

    a defect in ossification of bone.

  • FGFR2 wt Allele|BBDS|BEK|BEK Fibroblast Growth Factor Receptor Gene|BEK, Mouse, Homology of Gene|BFR-1|Bacteria-Expressed Kinase Gene|CD332|CEK3|CFD1|Craniofacial Dysostosis Gene|Crouzon Syndrome Gene|ECT1|FGFR2|Fibroblast Growth Factor Receptor 2 wt Allele|Fibroblast Growth Factor Receptor BEK Gene|JWS|Jackson-Weiss Syndrome Gene|K-SAM|KGFR Gene|KSAM-1|Keratinocyte Growth Factor Receptor Gene|Pfeiffer Syndrome Gene|Protein Tyrosine Kinase, Receptor-Like, 14 Gene|TK14|TK25

    human fgfr2 wild-type allele is located within 10q26 and is approximately 875 kb in length. this allele, which encodes fibroblast growth factor receptor 2 protein, plays a role in mitogenesis and differentiation by mediating the binding interactions of keratinocyte growth factor. mutations in the gene are associated with crouzon syndrome, pfeiffer syndrome, craniosynostosis, apert syndrome, jackson-weiss syndrome, beare-stevenson cutis gyrata syndrome, saethre-chotzen syndrome, and syndromic craniosynostosis.

  • Pycnodysostosis

    an autosomal recessive disorder caused by loss-of-function mutation(s) in the ctsk gene, encoding cathepsin k, an enzyme involved in bone resorption by osteoclasts. this condition is characterized by some or all of the following: osteosclerosis, short stature, pituitary hypoplasia with growth hormone deficiency, and cerebral demyelination.

  • Spondylocostal Dysostosis

    a rare disorder caused by mutations in the dll3 gene, mesp2 gene, lfng gene, or hes7 gene. it is characterized by abnormal development of bones in the spine and ribs.

  • Treacher Collins Syndrome|Mandibulofacial Dysostosis

    a rare autosomal dominant syndrome caused by mutations in the tcof1 gene. its characteristics include underdevelopment of the facial bones, small jaw and chin, absent or small ears, defects in the middle ear resulting in hearing loss, and downward sloping palpebral fissures.

  • Metatropic Dysplasia

    an autosomal dominant condition caused by mutation(s) in the trpv4 gene, encoding transient receptor potential cation channel subfamily v member 4. it is characterized by a variable phenotype, which may include short limbs, kyphoscoliosis, and other skeletal abnormalities.

  • Acroosteolysis

    a condition that is characterized by degeneration of the distal phalanges.

  • Melorheostosis

    a very rare bone disorder characterized by thickening of the cortex in a linear pattern. signs and symptoms include joint pain, joint swelling, limb deformity, and changes in the skin covering the bone lesion.

  • Kniest Dysplasia

    a rare, autosomal dominant inherited bone growth disorder caused by mutations in the col2a1gene. it is characterized by short stature (dwarfism) and other skeletal abnormalities, round, flat face with bulging and wide-set eyes, myopia and retinal detachment that can lead to blindness.

  • Osteopoikilosis

    a rare autosomal dominant inherited disorder characterized by the presence of small areas of increased density throughout the bones.

Patient EducationClinical

Birth Defects

A birth defect is a problem that happens while a baby is developing in the mother's body. Most birth defects happen during the first 3 months of pregnancy. One out of every 33 babies in the United States is born with a birth defect.

The full article covers:

  • What are birth defects?
  • What causes birth defects?
  • Who is at risk of having a baby with birth defects?
  • How are birth defects diagnosed?
  • What are the treatments for birth defects?
  • Can birth defects be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Q78.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
756.53 Osteopoikilosis
Approximate The match is approximate rather than exact.
ICD-9-CM
756.59 Osteodystrophy NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Q78.8Overview

Is Q78.8 (Other osteochondrodysplasias) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other specified osteochondrodysplasias on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does Q78.8 group to?

When other specified osteochondrodysplasias is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

Is Q78.8 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for other specified osteochondrodysplasias on inpatient claims.

What is the ICD-9 equivalent of Q78.8?

Under the General Equivalence Mappings, other specified osteochondrodysplasias converts to ICD-9-CM 756.53 (osteopoikilosis) and 756.59 (osteodystrophy NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.