2026 ICD-10-CM Diagnosis Code E83.39Other disorders of phosphorus metabolism

ICD-10-CM Codes›E00–E89›E70-E88›E83

ICD-10-CM E83.39
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E83.39 is a billable ICD-10-CM diagnosis code for other disorders of phosphorus metabolism. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E83.39
Billable Status
Yes — Valid for Submission
Code Describes
Other disorders of phosphorus metabolism
Short Description
Other disorders of phosphorus metabolism
Same as the full description in the CMS dataset.
Parent Code
E83.3
Disorders of phosphorus metabolism and phosphatases

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE83Disorders of mineral metabolism
This CodeE83.39Other disorders of phosphorus metabolism

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acid phosphatase deficiency
  • Acquired hypophosphatemia
  • Adult hypophosphatasia
  • Alkaline phosphatase above reference range
  • Childhood hypophosphatasia
  • Chronic myopathy with hypocalcemia and hypophosphatemia
  • Hyperphosphatasemia with bone disease
  • Hyperphosphatasemia with intellectual disability
  • Hyperphosphatemia
  • Hyperphosphatemia due to chronic kidney disease
  • Hyperphosphaturia
  • Hypophosphatasia
  • Hypophosphatasia rickets
  • Hypophosphatemia
  • Hypophosphatemia due to chronic kidney disease
  • Hypophosphaturia
  • Iatrogenic hyperphosphatemia
  • Idiopathic hyperphosphatasemia
  • Infantile hypophosphatasia
  • Nutritional hypophosphatemia
  • Odontohypophosphatasia
  • Periodontitis exacerbated by hypophosphatasia
  • Renal failure-associated hyperphosphatemia
  • Renal phosphaturia

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Acid phosphatase deficiency
  • Hypophosphatasia

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Acid
      • phosphatase deficiency
    • Deficiency, deficient
      • acid phosphatase
    • Diabetes, diabetic(mellitus) (sugar)
      • phosphate
    • Disorder(of)
      • metabolism NOS
        • phosphorus
          • acid phosphatase deficiency
    • Disorder(of)
      • metabolism NOS
        • phosphorus
          • hypophosphatasia
    • Disorder(of)
      • metabolism NOS
        • phosphorus
          • hypophosphatemia
    • Disorder(of)
      • metabolism NOS
        • phosphorus
          • other specified
    • Disturbance(s)
      • metabolism
        • phosphate
    • Hyperphosphatemia
    • Hypophosphatemia, hypophosphatasia(acquired) (congenital) (renal)
    • Phosphatemia
    • Phosphaturia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hypophosphatasia

    a genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. clinical manifestations include severe skeletal defects resembling vitamin d-resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes. (from dorland, 27th ed)

  • Hyperphosphatemia

    a condition of abnormally high level of phosphates in the blood, usually significantly above the normal range of 0.84-1.58 mmol per liter of serum.

  • Familial Hypophosphatemic Rickets

    a hereditary disorder characterized by hypophosphatemia; rickets; osteomalacia; renal defects in phosphate reabsorption and vitamin d metabolism; and growth retardation. autosomal and x-linked dominant and recessive variants have been reported.

  • Hypophosphatemia

    a condition of an abnormally low level of phosphates in the blood.

  • Hypophosphatemia, Familial

    an inherited condition of abnormally low serum levels of phosphates (below 1 mg/liter) which can occur in a number of genetic diseases with defective reabsorption of inorganic phosphorus by the proximal renal tubules. this leads to phosphaturia, hypophosphatemia, and disturbances of cellular and organ functions such as those in x-linked hypophosphatemic rickets; osteomalacia; and fanconi syndrome.

  • Rickets, Hypophosphatemic

    a disorder characterized by hypophosphatemia; rickets; osteomalacia; resulting from lack of phosphate reabsorption by the kidneys and possible defects in vitamin d metabolism.

  • Phosphates

    inorganic salts of phosphoric acid.

  • Hypophosphatasia

    a rare, serious metabolic disorder caused by mutations in the gene encoding tissue non-specific alkaline phosphatase (tnsalp) activity. it is characterized by low activity of tnsalp in the serum. the signs and symptoms vary significantly and include death in utero, failure to thrive, premature loss of deciduous teeth, early loss of the adult dentition, hypercalcemia, osteomalacia, skeletal defects, renal stones, and movement disorders.

  • Odontohypophosphatasia

    hypophosphastasia characterized by the premature loss of deciduous teeth, but without accompanying bony abnormalities.

  • Grade 1 Hyperphosphatemia, CTCAE|Grade 1 Hyperphosphatemia

    laboratory finding only and intervention not indicated

  • Grade 2 Hyperphosphatemia, CTCAE|Grade 2 Hyperphosphatemia

    noninvasive intervention indicated

  • Grade 3 Hyperphosphatemia, CTCAE|Grade 3 Hyperphosphatemia

    severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated

  • Grade 4 Hyperphosphatemia, CTCAE|Grade 4 Hyperphosphatemia

    life-threatening consequences; urgent intervention indicated (e.g., dialysis)

  • Grade 5 Hyperphosphatemia, CTCAE|Grade 5 Hyperphosphatemia

    death

  • Hyperphosphatemia

    abnormally high level of phosphate in the blood.

  • Hyperphosphatemia, CTCAE|Hyperphosphatemia

    a disorder characterized by laboratory test results that indicate an elevation in the concentration of phosphate in a blood.

  • Autosomal Dominant Hypophosphatemia Rickets|Autosomal Dominant Hypophosphatemic Rickets|Autosomal Dominant Vitamin D-resistant Rickets

    an autosomal dominant renal phosphate wasting disorder that results in rickets.

  • Autosomal Recessive Hypophosphatemia Rickets|Autosomal Recessive Hypophosphatemic Rickets

    an autosomal recessive renal phosphate wasting disorder that results in rickets.

  • Fibroblast Growth Factor 23|FGF-23|Phosphatonin|Tumor-Derived Hypophosphatemia Inducing Factor|Tumor-Derived Hypophosphatemia-Inducing Factor

    fibroblast growth factor 23 (251 aa, ~28 kda) is encoded by the human fgf23 gene. this protein is involved in inhibition of renal tubular phosphate transport.

  • Grade 1 Hypophosphatemia, CTCAE|Grade 1 Hypophosphatemia

    laboratory finding only and intervention not indicated

  • Grade 2 Hypophosphatemia, CTCAE|Grade 2 Hypophosphatemia

    oral replacement therapy indicated

  • Grade 3 Hypophosphatemia, CTCAE|Grade 3 Hypophosphatemia

    severe or medically significant but not immediately life-threatening; hospitalization or prolongation of existing hospitalization indicated

  • Grade 4 Hypophosphatemia, CTCAE|Grade 4 Hypophosphatemia

    life-threatening consequences

  • Grade 5 Hypophosphatemia, CTCAE|Grade 5 Hypophosphatemia

    death

  • Hypophosphatemia

    lower than normal levels of phosphates in the circulating blood.

  • Hypophosphatemia, CTCAE|Hypophosphatemia|Hypophosphatemia

    a disorder characterized by laboratory test results that indicate a low concentration of phosphates in the blood.

  • X-Linked Dominant Hypophosphatemic Rickets|Hereditary 1,25(OH)2D-resistant Rickets|Hypophosphatemic Vitamin D-resistant Rickets|Vitamin D-resistant Rickets|X-Linked Hypophosphatemia|X-linked Dominant Hypophosphatemic Rickets|X-linked Hypophosphatemic Rickets

    an x-linked dominant disorder caused by mutations in the phex gene. it is characterized by growth retardation, osteomalacia, hypophosphatemia, and defects in the renal reabsorption of phosphorus.

  • PHEX wt Allele|HPDR|HPDR1|HYP|HYP1|LXHR|PEX|PHEX Peptidase Gene|Phosphate Regulating Endopeptidase Homolog X-Linked Gene|Phosphate Regulating Endopeptidase X-Linked wt Allele|Phosphate Regulating Gene with Homologies to Endopeptidases on the X Chromosome (Hypophosphatemia, Vitamin D Resistant Rickets) Gene|Phosphate-Regulating Endopeptidase Homolog, X-Linked Gene|Phosphate-Regulating Endopeptidase, X-Linked Gene|Phosphate-Regulating Neutral Endopeptidase Gene|XLH

    human phex wild-type allele is located in the vicinity of xp22.11 and is approximately 462 kb in length. this allele, which encodes phosphate-regulating neutral endopeptidase phex protein, is involved in the cleavage of peptides that mediates osteogenic cell differentiation, bone mineralization, dentin mineralization and renal phosphate reabsorption. mutations in the gene are associated with x-linked dominant hypophosphatemic rickets.

  • Phosphate-Regulating Neutral Endopeptidase PHEX|EC 3.4.24.-|HYP|Metalloendopeptidase Homolog PEX|PHEX|Vitamin D-Resistant Hypophosphatemic Rickets Protein|X-Linked Hypophosphatemia Protein

    phosphate-regulating neutral endopeptidase phex (749 aa, ~86 kda) is encoded by the human phex gene. this protein plays a role in the cleavage of biologically active small integrin-binding ligand, n-linked glycoprotein (sibling)-derived acidic-serine-aspartate-rich-mepe-associated (asarm) motif peptides.

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E83.39 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
275.3 Dis phosphorus metabol
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E83.39Overview

Is E83.39 (Disorders of phosphorus metabolism and phosphatases) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other disorders of phosphorus metabolism on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of E83.39?

Under the General Equivalence Mappings, other disorders of phosphorus metabolism converts to ICD-9-CM 275.3 (dis phosphorus metabol). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.