2026 ICD-10-CM Diagnosis Code E75.5Other lipid storage disorders

ICD-10-CM Codes›E00–E89›E70-E88›E75

ICD-10-CM E75.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E75.5 is a billable ICD-10-CM diagnosis code for other lipid storage disorders. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E75.5
Billable Status
Yes — Valid for Submission
Code Describes
Other lipid storage disorders
Short Description
Other lipid storage disorders
Same as the full description in the CMS dataset.
Parent Code
E75
Disorders of sphingolipid metabolism and other lipid storage disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE75Disorders of sphingolipid metabolism and other lipid storage disorders
This CodeE75.5Other lipid storage disorders

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Ataxia due to cerebrotendinous xanthomatosis
  • Chemically-induced lipidosis
  • Cholestanol storage disease
  • Cholesterol ester storage disease
  • Disorder of cholesterol catabolism
  • Disorder of cholesterol metabolism
  • Disorder of lipid storage and metabolism
  • Disorder of sialic acid metabolism
  • Familial disease with storage of sterols
  • Lipid storage myopathy
  • Lysosomal acid lipase deficiency
  • Neutral lipid storage disease with myopathy
  • Papular xanthoma
  • Primary triglyceride deposit cardiomyovasculopathy
  • Pulmonary lipid storage disease
  • Salla disease
  • Sialic storage disease
  • Sitosterolemia
  • Sitosterolemia with xanthomatosis
  • Synthetic defect of bile acids
  • Triglyceride storage disease with ichthyosis
  • Wolman's disease
  • Xanthoma due to abnormality of lipid metabolism
  • Xanthoma due to lipid storage disease
  • Xanthoma of lung
  • Xanthoma tendinosum

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Cerebrotendinous cholesterosis van Bogaert-Scherer-Epstein
  • Wolman's disease

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Cholesterolosis, cholesterosis(gallbladder)
      • cerebrotendinous
    • Disease, diseased
      • lipid-storage
        • specified NEC
    • Disease, diseased
      • triglyceride-storage
    • Disorder(of)
      • lipid
        • storage
          • specified NEC
    • Hyperlipidosis
      • hereditary NEC
    • Lipidosis
      • cholesterol (cerebral)
    • Van Bogaert-Scherer-Epstein disease or syndrome
    • Wolman's disease
    • Xanthoma(s), xanthomatosis (primary) (familial) (hereditary)
      • cerebrotendinous
    • Xanthoma(s), xanthomatosis (primary) (familial) (hereditary)
      • cutaneotendinous
    • Xanthoma(s), xanthomatosis (primary) (familial) (hereditary)
      • joint
    • Xanthoma(s), xanthomatosis (primary) (familial) (hereditary)
      • tendon (sheath)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Cholesterol Ester Storage Disease

    an autosomal recessive disorder caused by mutations in the gene for acid lipase (sterol esterase). it is characterized by the accumulation of neutral lipids, particularly cholesterol esters in leukocytes, fibroblasts, and hepatocytes.

  • Sitosterolemia

    an extremely rare autosomal recessive inherited disorder caused by mutations in the abcg5 or abcg8 genes. it is characterized by a defective sterolin transporter that impairs the elimination of plant sterols and, to a lesser degree, cholesterol from the body. these fatty substances build up in the tissues including arteries and skin, resulting in atherosclerosis and xanthomas.

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E75.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
272.8 Lipoid metabol dis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E75.5Overview

Is E75.5 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other lipid storage disorders on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of E75.5?

Under the General Equivalence Mappings, other lipid storage disorders converts to ICD-9-CM 272.8 (lipoid metabol dis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.