2026 ICD-10-CM Diagnosis Code E50.8Other manifestations of vitamin A deficiency

ICD-10-CM Codes›E00–E89›E50-E64›E50

ICD-10-CM E50.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E50.8 is a billable ICD-10-CM diagnosis code for other manifestations of vitamin A deficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. Coders also document this condition as inverted follicular keratosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nutritional deficiencies.

Code Identity

ICD-10-CM Code
E50.8
Billable Status
Yes — Valid for Submission
Code Describes
Other manifestations of vitamin A deficiency
Short Description
Other manifestations of vitamin A deficiency
Same as the full description in the CMS dataset.
Parent Code
E50
Vitamin A deficiency

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE50-E64Other nutritional deficiencies
CategoryE50Vitamin A deficiency
This CodeE50.8Other manifestations of vitamin A deficiency

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Inverted follicular keratosis
  • Phrynoderma
  • Vitamin A deficiency with follicular keratosis
  • Vitamin A deficiency with xeroderma

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Follicular keratosis
  • Xeroderma

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deficiency, deficient
      • vitamin (multiple) NOS
        • A
          • with
            • follicular keratosis
    • Deficiency, deficient
      • vitamin (multiple) NOS
        • A
          • with
            • manifestations NEC
    • Deficiency, deficient
      • vitamin (multiple) NOS
        • A
          • with
            • xeroderma
    • Keratosis
      • follicularis
        • vitamin A deficiency
    • Keratosis
      • vitamin A deficiency
    • Phrynoderma(vitamin A deficiency)
    • Xeroderma
      • vitamin A deficiency

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END007
Nutritional deficiencies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Phrynoderma

    rough, dry, hypertrophic eruption of the skin associated with vitamin a deficiency.

  • Inverted Follicular Keratosis

    seborrheic keratosis that arises from follicular structures in the skin. it presents as a solitary nodule in the skin and is characterized by the presence of prominent squamous eddies.

  • Vulvar Inverted Follicular Keratosis

    seborrheic keratosis that arises from follicular structures in the vulva. it is characterized by the presence of prominent squamous eddies.

  • Eyelid Inverted Follicular Keratosis

    a benign eyelid tumor that presents with asymptomatic papules and is characterized by the proliferation of squamous and basaloid cells of the follicular infundibulum.

Patient EducationClinical

Malnutrition

Malnutrition means that your body isn't getting enough calories or the right balance of nutrients to stay healthy. This can happen if you don't get enough protein, carbohydrates, and fats, eat too much unhealthy food, or don't get the vitamins and minerals your body needs.

The full article covers:

  • What is malnutrition?
  • What are the types of malnutrition?
  • What causes malnutrition?
  • Who is at risk for developing malnutrition?
  • What are the symptoms of malnutrition?
  • How is malnutrition diagnosed?
  • What are the treatments for malnutrition?
  • Can malnutrition be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E50.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
264.8 Vitamin A deficiency NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E50.8Overview

Is E50.8 (Vitamin A deficiency) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other manifestations of vitamin A deficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E50.8 group to?

When other manifestations of vitamin A deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E50.8?

Under the General Equivalence Mappings, other manifestations of vitamin A deficiency converts to ICD-9-CM 264.8 (vitamin A deficiency NEC). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.