2024 ICD-10-CM Diagnosis Code L57.0

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Acantholytic actinic keratosis
• Actinic keratosis
• Actinic keratosis of eyelid
• Adverse effect from PUVA photochemotherapy
• Atrophic actinic keratosis
• Benign neoplasm of skin of forehead
• Benign neoplasm of skin of hand
• Benign neoplasm of skin of left lower limb
• Benign neoplasm of skin of left upper limb
• Benign neoplasm of skin of right lower limb
• Benign neoplasm of skin of right upper limb
• Benign neoplasm of skin of scalp
• Benign neoplasm of skin of temporal region
• Benign neoplasm of soft tissue of hand
• Bilateral benign neoplasm of skin of lower limbs
• Bilateral mass of skin of hands
• Bowenoid actinic keratosis
• Diffuse actinic hyperkeratosis
• Hyperkeratotic actinic keratosis
• Hypertrophic solar keratosis
• Keratosis
• Lichenoid actinic keratosis
• Multiple actinic keratoses
• Multiple actinic keratoses
• Multiple actinic keratoses involving face
• Multiple actinic keratoses involving forehead and temples
• Multiple actinic keratoses involving hands
• Multiple actinic keratoses involving legs
• Multiple actinic keratoses involving scalp
• Orthokeratosis
• Pigmented actinic keratosis
• Plane basal cell papilloma
• Proliferative actinic keratosis
• Psoralen and long-wave ultraviolet radiation keratosis
• Radiation keratosis following radiotherapy
• Radiation-induced keratosis
• Radiation-induced keratosis
• Senile hyperkeratosis

Clinical Information

• Darier Disease

  an autosomal dominantly inherited skin disorder characterized by warty malodorous papules that coalesce into plaques. it is caused by mutations in the atp2a2 gene encoding serca2 protein, one of the sarcoplasmic reticulum calcium-transporting atpases. the condition is similar, clinically and histologically, to benign familial pemphigus, another autosomal dominant skin disorder. both diseases have defective calcium pumps (calcium-transporting atpases) and unstable desmosomal adhesion junctions (desmosomes) between keratinocytes.

• Keratoderma, Palmoplantar

  group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).

• Keratoderma, Palmoplantar, Diffuse

  an autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. there is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (keratoderma, palmoplantar), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present.

• Keratoderma, Palmoplantar, Epidermolytic

  an autosomal dominant hereditary skin disease characterized by epidermolytic hyperkeratosis that is strictly confined to the palms and soles. it has been associated with mutations in the gene that codes for keratin-9.

• Keratosis

  any horny growth such as a wart or callus.

• Keratosis, Actinic

  white or pink lesions on the arms, hands, face, or scalp that arise from sun-induced dna damage to keratinocytes in exposed areas. they are considered precursor lesions to superficial squamous cell carcinoma.

• Keratosis, Seborrheic

  benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. the age of onset is usually in the fourth or fifth decade.

• Leukoplakia, Oral

  a white patch seen on the oral mucosa. it is considered a premalignant condition and is often tobacco-induced. when evidence of epstein-barr virus is present, the condition is called hairy leukoplakia (leukoplakia, hairy).

• Papillon-Lefevre Disease

  rare, autosomal recessive disorder occurring between the first and fifth years of life. it is characterized by palmoplantar keratoderma with periodontitis followed by the premature shedding of both deciduous and permanent teeth. mutations in the gene for cathepsin c have been associated with this disease.

• Tyrosinemias

  a group of disorders which have in common elevations of tyrosine in the blood and urine secondary to an enzyme deficiency. type i tyrosinemia features episodic weakness, self-mutilation, hepatic necrosis, renal tubular injury, and seizures and is caused by a deficiency of the enzyme fumarylacetoacetase. type ii tyrosinemia features intellectual disability, painful corneal ulcers, and keratoses of the palms and plantar surfaces and is caused by a deficiency of the enzyme tyrosine transaminase. type iii tyrosinemia features intellectual disability and is caused by a deficiency of the enzyme 4-hydroxyphenylpyruvate dioxygenase. (menkes, textbook of child neurology, 5th ed, pp42-3)

• Keratin-9

  a type ii keratin found predominantly expressed in the terminally differentiated epidermis of palms and soles. mutations in the gene for keratin 9 are associated with keratoderma, palmoplantar, epidermolytic.

• Acrokeratosis Verruciformis|Acrokeratosis Verruciformis of Hopf

  a rare genetic skin keratinization disorder with an autosomal dominant mode of inheritance. it is characterized by numerous flesh-colored warty papules on the back of the hands, medial aspect of the feet, knees, and elbows.

• Actinic Keratosis|Actinic (Solar) Keratosis|Actinic (Solar) Keratosis|Senile Hyperkeratosis|Senile Keratosis|Solar Keratosis|actinic keratosis|senile keratosis|solar keratosis

  a precancerous lesion of the skin composed of atypical keratinocytes. it is characterized by the presence of thick, scaly patches of skin. several histologic variants have been described, including atrophic, acantholytic, and hyperkeratotic variants.

• Arsenical Keratosis|ASK

  a hyperkeratotic skin lesion that occurs in patients who have been exposed to arsenic.

• Darier Disease|Keratosis Follicularis

  an autosomal dominant inherited chronic skin disorder caused by mutations in the atp2a2 gene. it is characterized by the development of yellow-brown keratotic skin papules in the neck, ears, forehead, chest, back and groin. it is associated with fragility of the free margins of the nails.

• DKC1 wt Allele|CBF5|DKC|DKCX|Dyskeratosis Congenita 1, Dyskerin Gene|Dyskerin Pseudouridine Synthase 1 wt Allele|NAP57|NOLA4|XAP101

  human dkc1 wild-type allele is located in the vicinity of xq28 and is approximately 15 kb in length. this allele, which encodes h/aca ribonucleoprotein complex subunit 4 protein, plays a role in the stabilization and maintenance of telomerase and h/aca small nucleolar rna ribonucleoprotein biogenesis. mutation of the gene is associated with both hoyeraal-hreidarsson syndrome and x-linked dyskeratosis congenita.

• Dyskeratosis Congenita, Autosomal Dominant 1|DKCA1|Dyskeratosis Congenita, Scoggins Type

  dyskeratosis congenita caused by autosomal dominant mutation(s) in the terc gene, encoding telomerase rna component.

• Dyskeratosis Congenita, Autosomal Dominant 2|DKCA2|DKCB4|Dyskeratosis Congenita, Autosomal Recessive 4

  dyskeratosis congenita caused by mutation(s) in the tert gene, encoding telomerase reverse transcriptase.

• Dyskeratosis Congenita, Autosomal Dominant 3|DKCA3

  dyskeratosis congenita caused by autosomal dominant mutation(s) in the tinf2 gene, encoding terf1-interacting nuclear factor 2. mutations in tinf2 may also lead to another phenotype known as revesz syndrome (dyskeratosis congenita, autosomal dominant 5).

• Dyskeratosis Congenita, Autosomal Dominant 6|DKCA6|DKCB7|Dyskeratosis Congenita, Autosomal Recessive 7

  dyskeratosis congenita caused by mutation(s) in the acd gene, encoding adrenocortical dysplasia protein homolog.

• Dyskeratosis Congenita, Autosomal Recessive 1|DKCB1

  dyskeratosis congenita caused by autosomal recessive mutation(s) in the nop10 gene, encoding h/aca ribonucleoprotein complex subunit 3.

• Dyskeratosis Congenita, Autosomal Recessive 2|DKCB2

  dyskeratosis congenita caused by autosomal recessive mutation(s) in the nhp2 gene, encoding h/aca ribonucleoprotein complex subunit 2.

• Dyskeratosis Congenita, Autosomal Recessive 3|DKCB3

  dyskeratosis congenita caused by autosomal recessive mutation(s) in the wrap53 gene, encoding telomerase cajal body protein 1.

• Dyskeratosis Congenita, Autosomal Recessive 5|DKCA4|DKCB5|Dyskeratosis Congenita, Autosomal Dominant 4

  dyskeratosis congenita caused by mutation(s) in the rtel1 gene, encoding regulator of telomere elongation helicase 1.

• Dyskeratosis Congenita, Autosomal Recessive 6|DKCB6

  dyskeratosis congenita caused by autosomal recessive mutation(s) in the parn gene, encoding poly(a)-specific ribonuclease parn.

• Dyskeratosis Congenita|DKC|Zinsser-Engman-Cole Syndrome

  a rare genetic disorder characterized by nail dystrophy, reticulated skin pigmentation especially on the neck and chest, and oral leukoplakia. in about half the cases mutations in the tert, terc, dkc1, or tinf2 genes are identified. patients are at an increased risk of developing bone marrow failure, myelodysplastic syndrome, leukemia, or cancer, especially in the head and neck region.

• Epidermolytic Ichthyosis|BCIE|Bullous Congenital Ichthyosiform Erythroderma|Epidermolytic Hyperkeratosis

  an autosomal dominant inherited skin disorder caused by mutations in the krt1 and krt10 genes. it is manifested at birth and is characterized by generalized erythema, skin blisters and skin fragility.

• External Ear Actinic Keratosis|Actinic Keratosis of External Ear|Actinic Keratosis of the External Ear

  actinic keratosis that develops in the skin of the external ear.

• Eyelid Seborrheic Keratosis|Basal Cell Papilloma of Eyelid|Basal Cell Papilloma of the Eyelid|Eyelid Basal Cell Papilloma|Seborrheic Keratosis of Eyelid|Seborrheic Keratosis of the Eyelid

  a benign skin neoplasm that arises from the eyelid. it is characterized by the intraepidermal proliferation of basaloid keratinocytes, acanthosis, hyperkeratosis, and cysts formation.

• Grade 1 Hyperkeratosis, CTCAE|Grade 1 Hyperkeratosis

  present

• Grade 3 Hyperkeratosis, CTCAE|Grade 3 Hyperkeratosis

  limiting self-care adls

• Hereditary Benign Intraepithelial Dyskeratosis|HBID|Witkop-Von Sallmann Disease

  a rare genetic disorder with an autosomal dominant pattern of inheritance with variable penetrance. it was initially described among native americans belonging to the haliwa-saponi tribe of northeastern north carolina. it is caused by a duplication of chromosomal dna at 4q35. clinical signs present in early childhood and include asymptomatic plaques of the epibulbar conjunctivae and oral mucosa. clinical progression of the plaques to malignancy has not been reported.

• Hereditary Leukokeratosis|Cannon Disease|Hereditary Mucosal Leukokeratosis|White Sponge Nevus|White Sponge Nevus of Cannon

  an autosomal dominant inherited disorder characterized by thickened and spongy oral mucosa with a white tint. it may affect other anatomic sites as well.

• Hyperkeratosis, CTCAE|Hyperkeratosis

  a disorder characterized by a thickening of the outer layer of the skin.

• Hyperkeratosis|HYPERKERATOSIS|Increased Keratinization|hyperkeratosis

  hypertrophy of the outermost layer of the epidermis. it may be caused by physical or chemical irritants, irradiation, infection, or neoplastic processes.

• Hyperparakeratosis

  a morphologic finding indicating increased keratin formation, preservation of the nuclei in the superficial cells, and absence of the stratum granulosum in a skin or squamous mucosa sample.

• Hyperplasia and Hyperkeratosis|HYPERPLASIA/HYPERKERATOSIS

  a finding that generally has features of hyperplasia and hyperkeratosis.

• Inverted Follicular Keratosis

  seborrheic keratosis that arises from follicular structures in the skin. it presents as a solitary nodule in the skin and is characterized by the presence of prominent squamous eddies.

• Keratin, Type I Cytoskeletal 10|Cytokeratin 10|Cytokeratin-10|KRT10|Keratin-10|Keratosis Palmaris Et Plantaris

  keratin, type i cytoskeletal 10 (584 aa, ~59 kda) is encoded by the human krt10 gene. this protein plays a role in the structure of intermediate filaments.

• Keratosis

  excessive growth of keratin on the skin.

• Keratosis Pilaris|KP

  a very common, non-neoplastic dermatologic disorder characterized by keratinization of hair follicles of the skin. it manifests as small, rough folliculocentric keratotic papules, usually in the outer-upper arms and thighs. it affects children and adolescents and usually improves with age.

• KRT1 wt Allele|CK1|EHK|EHK1|EPPK|Epidermolytic Hyperkeratosis 1 Gene|K1|KRT1A|Keratin 1 wt Allele|NEPPK

  human krt1 wild-type allele is located within 12q12-q13 and is approximately 6 kb in length. this allele, which encodes keratin, type ii cytoskeletal 1 protein, plays a role in the regulation of epidermal development. mutation of the gene is associated with bullous congenital ichthyosiform erythroderma, ichthyosis hystrix curth-macklin type, palmoplantar keratoderma non-epidermolytic, ichthyosis annular epidermolytic and palmoplantar keratoderma striate type 3.

• KRT10 wt Allele|BCIE|BIE|CK-10|CK10|EHK|Epidermolytic Hyperkeratosis Gene|K10|KPP|Keratin 10 wt Allele

  human krt10 wild-type allele is located in the vicinity of 17q21 and is approximately 4 kb in length. this allele, which encodes keratin, type i cytoskeletal 10 protein, is involved in the intermediate filament structure of terminally differentiated epidermal cells. mutations in this gene are associated with epidermolytic hyperkeratosis, ichthyosis with confetti, and cyclic ichthyosis with epidermolytic hyperkeratosis.

• Laryngeal Keratosis|Keratosis of Larynx|Keratosis of the Larynx|Laryngeal Leukoplakia

  a premalignant pathologic process that affects the mucosal epithelium of the larynx. it appears as a localized or diffuse white patch on the laryngeal mucosa. morphologically it is characterized by the pathologic production of keratin in the mucosal epithelial surface with or without epithelial atypia. it may progress to or co-exist with invasive squamous cell carcinoma.

• Lichen Planus-Like Keratosis|Lichenoid Keratosis

  a benign intraepidermal squamoproliferative neoplasm characterized by irregular acanthosis, hyperkeratosis, parakeratosis, and prominent chronic inflammation.

• Oral Cavity Hairy Leukoplakia|Hairy Leukoplakia of Mouth|Hairy Leukoplakia of Oral Mucosa|Hairy Leukoplakia of the Mouth|Hairy Leukoplakia of the Oral Mucosa|Mouth Hairy Leukoplakia|Oral Hairy Keratosis

  an epithelial hyperplasia of the oral cavity mucosa associated with epstein-barr virus and found almost exclusively in persons with hiv infection. the lesion consists of a white patch that is often corrugated or hairy.

• Oral Leukoplakia|Leukokeratosis of Oral Mucosa|Leukoplakia of Oral Mucosa|Leukoplakia of the Oral Mucosa|Oral Keratoses|Oral Keratosis

  a white patch or plaque on the oral mucosa that cannot be characterized clinically or pathologically as any other disease. the diagnosis of leukoplakia is one of exclusion; other conditions such as candidiasis, lichen planus, leukoedema, etc., must be ruled out before a diagnosis of leukoplakia can be made. leukoplakia may be a premalignant condition.

• Orthokeratosis

  the formation of an epidermal layer which lacks nuclei during normal keratinization.

• Parakeratosis

  abnormal retention of nuclei, and the resulting incomplete keratinization, of epithelial cells in the stratum corneum layer of the skin.

• Porokeratosis

  a clonal proliferation of abnormal keratinocytes characterized by the development of localized or multiple atrophic skin patches surrounded by an annular keratotic ring called cornoid lamella.

• PUVA Keratosis

  a hyperkeratotic skin lesion that occurs in patients with a history of prolonged exposure to psoralen and ultraviolet a (puva) therapy.

• Revesz Syndrome|DKCA5|Dyskeratosis Congenita, Autosomal Dominant, 5|Exudative Retinopathy with Bone Marrow Failure

  an autosomal dominant form of dyskeratosis congenita, caused by mutation(s) in the tinf2 gene, encoding terf1-interacting nuclear factor 2. it is a fatal disease associated with exudative retinopathy and bone marrow failure.

• Seborrheic Keratosis|Basal Cell Papilloma|Keratosis Seborrheica

  a common benign neoplasm usually affecting older individuals. the lesions usually arise in the trunk, head and neck, but they can occur on any skin surface other than the palms, soles, and mucosal surfaces. they appear as flat-based papules or plaques. histologically, there is intraepidermal proliferation of basaloid keratinocytes, acanthosis, hyperkeratosis, and cysts formation.

• Smoker's Keratosis

  a premalignant pathologic process that affects the oral mucosa. it is associated with the use of smoked tobacco. it appears as white lesions on the oral mucosa. morphologically it is characterized by the pathologic production of keratin in the mucosal epithelial surface with or without epithelial atypia. it may reverse with the cessation of tobacco use.

• Tobacco Induced Hyperparakeratosis

  hyperparakeratosis of the oral mucosa caused by chronic tobacco use. it manifests as oral leukoplakia.

• Tylosis|Keratosis Palmaris et Plantaris

  an inherited disorder characterized by the development of keratotic lesions on the palms and soles. it appears in childhood as redness on the palms and soles which progresses to well demarcated, thickened, yellowish and waxy lesions.

• Vulvar Inverted Follicular Keratosis

  seborrheic keratosis that arises from follicular structures in the vulva. it is characterized by the presence of prominent squamous eddies.

• Vulvar Seborrheic Keratosis|Seborrheic Keratosis of Vulva|Seborrheic Keratosis of the Vulva

  a benign squamous neoplasm that arises from the vulva. it is characterized by the proliferation of the basal cells in the squamous epithelium, acanthosis, hyperkeratosis, and cysts formation.

• Warty Dyskeratoma|Follicular Dyskeratoma|Isolated Follicular Keratosis

  a rare, usually solitary, benign epithelial tumor of the skin that appears to arise from a hair follicle. it usually develops in the head and neck region as a nodular lesion with a central keratotic plug.

• X-Linked Dyskeratosis Congenita|Hoyeraal Hreidarsson Syndrome

  dyskeratosis congenita inherited in an x-linked recessive pattern. it is caused by mutations in the dkc1 gene.

L57.0 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

MS-DRG	MS-DRG Title	MCD	Relative Weight
606	MINOR SKIN DISORDERS WITH MCC	09	1.5858
607	MINOR SKIN DISORDERS WITHOUT MCC	09	0.8935

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Convert L57.0 to ICD-9-CM

• ICD-9-CM Code: 702.0 - Actinic keratosis

Patient Education

Skin Conditions

What does your skin do?

Your skin is your body's largest organ. It covers the entire outside of your body. There are many ways that your skin protects your body and helps keep you healthy. For example, it:

• Holds body fluids in, which helps prevent you from getting dehydrated
• Keeps out harmful germs, which helps prevent infections
• Helps you feel things like heat, cold, and pain
• Helps control your body temperature
• Makes vitamin D when the sun shines on it
• Shields your body against heat and light

What problems and conditions can affect your skin?

There are many different problems and conditions which can affect your skin. Some of them can cause uncomfortable symptoms, such as itching, burning, redness, and rashes. They might also affect your appearance. Some of the more common skin conditions include:

• Acne, which causes pimples when hair follicles under your skin get clogged up
• Burns
• Cuts and scrapes
• Dandruff, flaking of the skin on your scalp (the top of your head)
• Eczema (atopic dermatitis), which causes inflammation, redness, and irritation of the skin
• Hives, which are red and sometimes itchy bumps on your skin
• Insect bites
• Psoriasis, which causes itchy, scaly red patches
• Skin cancer
• Skin infections

How can I keep my skin healthy?

Since your skin protects your body in many ways, it's important to try to keep your skin healthy. For example, you can:

• Wear the right protective equipment, like gloves, long sleeves, knee and elbow pads, or helmets to protect against cuts, bumps and scrapes.
• If you do get a cut or scrape, clean it right away with soap and warm water. Put on a bandage to protect it while it heals.
• When you are spending time outdoors, wear long sleeves and pants and use insect repellant to prevent insect bites.
• Prevent sunburn by covering up and using sunscreen when outdoors.
• Wash your hands often with soap and water.
• When you take a shower or bath, use warm (not hot) water. Use mild cleansers and wash gently (don't scrub).
• Use moisturizers, like lotions, creams, or ointments, to prevent dry skin.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

[Learn More in MedlinePlus]

Sun Exposure

Ultraviolet (UV) rays are an invisible form of radiation. They can pass through your skin and damage your skin cells. Sunburns are a sign of skin damage. Suntans aren't healthy, either. They appear after the sun's rays have already killed some cells and damaged others. UV rays can cause skin damage during any season or at any temperature. They can also cause eye problems, wrinkles, skin spots, and skin cancer.

To protect yourself :

• Stay out of the sun when it is strongest (between 10 a.m. and 2 p.m.)
• Use sunscreen with an SPF of 15 or higher
• Wear protective clothing
• Wear wraparound sunglasses that provide 100% UV ray protection
• Avoid sunlamps and tanning beds

Check your skin regularly for changes in the size, shape, color, or feel of birthmarks, moles, and spots. Such changes are a sign of skin cancer.

Food and Drug Administration

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Skin Cancer Treatment (PDQ®)

Learn about skin cancer risk factors, signs and symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.