2027 ICD-10-CM Diagnosis Code D75.1Secondary polycythemia
ICD-10-CM Codes›D50–D89›D70-D77›D75
- Billable — Valid for Submission
- Chronic Condition
D75.1 is a billable ICD-10-CM diagnosis code for secondary polycythemia. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 814 through 816. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified hematologic conditions.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Autosomal dominant secondary polycythemia
- Autosomal recessive secondary polycythemia not associated with VHL gene
- Effects of high altitude
- Erythrocytosis
- Erythrocytosis caused by low atmospheric pressure
- Erythrocytosis due to alveolar hypoventilation
- Erythrocytosis due to autotransfusion
- Erythrocytosis due to cardiovascular disease
- Erythrocytosis due to cerebellar hemangioma
- Erythrocytosis due to cyanotic congenital heart disease
- Erythrocytosis due to defective oxygen transport
- Erythrocytosis due to endocrine disorder
- Erythrocytosis due to hepatoma
- Erythrocytosis due to hydronephrosis
- Erythrocytosis due to pulmonary disease
- Erythrocytosis due to renal cyst
- Erythrocytosis due to renal neoplasm
- Erythrocytosis due to tissue hypoxemia
- Erythrocytosis due to uterine myoma
- Familial erythrocytosis
- Gaisbock's syndrome
- Hemoglobinopathy with erythrocytosis
- High oxygen affinity hemoglobin polycythemia
- Idiopathic erythrocytosis
- Inappropriate secondary erythrocytosis
- Multiple paraganglioma associated with polycythemia
- Paraganglioma
- Polycythemia due to cyanotic heart disease
- Polycythemia due to cyanotic respiratory disease
- Polycythemia due to HIF2A mutation
- Polycythemia due to PHD2 mutation
- Pseudo-polycythemia
- Relative polycythemia
- Relative polycythemia due to acute loss of plasma volume
- Relative polycythemia due to chronic loss of plasma volume
- Secondary polycythemia
- Secondary polycythemia with excess erythropoietin
- Secondary polycythemia without excess erythropoietin
- Stress polycythemia
- TEMPI syndrome
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to D75.1: its own notes plus those printed at D75 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Acquired polycythemia
- Emotional polycythemia
- Erythrocytosis NOS
- Hypoxemic polycythemia
- Nephrogenous polycythemia
- Polycythemia due to erythropoietin
- Polycythemia due to fall in plasma volume
- Polycythemia due to high altitude
- Polycythemia due to stress
- Polycythemia NOS
- Relative polycythemia
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name D75.1, its category, or a range that includes it.
Excludes1 4
These codes carry an Excludes1 note naming D75.1: they are not reported together with it, unless the two conditions are unrelated.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
secondary D75.1
Polycythemia (secondary) D75.1
acquired D75.1
erythropoietin D75.1
fall in plasma volume D75.1
high altitude D75.1
stress D75.1
emotional D75.1
erythropoietin D75.1
Gaisböck's (hypertonica) D75.1
high altitude D75.1
hypertonica D75.1
hypoxemic D75.1
nephrogenous D75.1
relative D75.1
secondary D75.1
spurious D75.1
stress D75.1
Polycytosis cryptogenica D75.1
Pseudopolycythemia D75.1
polycythemia D75.1
Syndrome See Also: Disease;
Gaisböck's D75.1
polycythemic D75.1
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Polycythemia
an increase in the total red cell mass of the blood. (dorland, 27th ed)
Patient EducationClinical
Blood Disorders
Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D75.1 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D75.1Overview
What is the ICD-10 code for secondary polycythemia?
The ICD-10-CM code for secondary polycythemia is D75.1 (sometimes written as D751). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is D75.1 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report secondary polycythemia on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does D75.1 group to?
When secondary polycythemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 816, 814, 815, with relative weights from 0.7378 to 2.0727 depending on complications. Higher weights mean higher Medicare reimbursement.
Can D75.1 be reported with P61.1?
Not as a rule. The Excludes1 note on D75.1 lists "polycythemia neonatorum (P61.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of D75.1?
Under the General Equivalence Mappings, secondary polycythemia converts to ICD-9-CM 289.0 (secondary polycythemia). The mapping is a direct match.
