2026 ICD-10-CM Diagnosis Code D75.1Secondary polycythemia

ICD-10-CM Codes›D50–D89›D70-D77›D75

ICD-10-CM D75.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D75.1 is a billable ICD-10-CM diagnosis code for secondary polycythemia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified hematologic conditions.

Code Identity

ICD-10-CM Code
D75.1
Billable Status
Yes — Valid for Submission
Code Describes
Secondary polycythemia
Short Description
Secondary polycythemia
Same as the full description in the CMS dataset.
Parent Code
D75
Other and unspecified diseases of blood and blood-forming organs

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD75Other and unspecified diseases of blood and blood-forming organs
This CodeD75.1Secondary polycythemia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Autosomal dominant secondary polycythemia
  • Autosomal recessive secondary polycythemia not associated with VHL gene
  • Effects of high altitude
  • Erythrocytosis
  • Erythrocytosis caused by low atmospheric pressure
  • Erythrocytosis due to alveolar hypoventilation
  • Erythrocytosis due to autotransfusion
  • Erythrocytosis due to cardiovascular disease
  • Erythrocytosis due to cerebellar hemangioma
  • Erythrocytosis due to cyanotic congenital heart disease
  • Erythrocytosis due to defective oxygen transport
  • Erythrocytosis due to endocrine disorder
  • Erythrocytosis due to hepatoma
  • Erythrocytosis due to hydronephrosis
  • Erythrocytosis due to pulmonary disease
  • Erythrocytosis due to renal cyst
  • Erythrocytosis due to renal tumor
  • Erythrocytosis due to tissue hypoxemia
  • Erythrocytosis due to uterine myoma
  • Familial erythrocytosis
  • Gaisbock's syndrome
  • Hemoglobinopathy with erythrocytosis
  • High oxygen affinity hemoglobin polycythemia
  • Idiopathic erythrocytosis
  • Inappropriate secondary erythrocytosis
  • Multiple paraganglioma associated with polycythemia
  • Paraganglioma
  • Polycythemia due to cyanotic heart disease
  • Polycythemia due to cyanotic respiratory disease
  • Polycythemia due to HIF2A mutation
  • Polycythemia due to PHD2 mutation
  • Pseudo-polycythemia
  • Relative polycythemia
  • Relative polycythemia due to acute loss of plasma volume
  • Relative polycythemia due to chronic loss of plasma volume
  • Secondary polycythemia
  • Secondary polycythemia with excess erythropoietin
  • Secondary polycythemia without excess erythropoietin
  • Stress polycythemia
  • TEMPI syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Acquired polycythemia
  • Emotional polycythemia
  • Erythrocytosis NOS
  • Hypoxemic polycythemia
  • Nephrogenous polycythemia
  • Polycythemia due to erythropoietin
  • Polycythemia due to fall in plasma volume
  • Polycythemia due to high altitude
  • Polycythemia due to stress
  • Polycythemia NOS
  • Relative polycythemia

Type 1 Excludes

  • polycythemia neonatorum P61.1
  • polycythemia vera D45

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • Gaisböck's (polycythemia hypertonica)
    • Effect, adverse
      • high altitude NEC
        • polycythemia
    • Erythremia(acute)
      • secondary
    • Erythrocytosis(megalosplenic) (secondary)
    • Erythrocytosis(megalosplenic) (secondary)
      • secondary
    • Erythrocytosis(megalosplenic) (secondary)
      • stress
    • Gaisböck's disease(polycythemia hypertonica)
    • High
      • altitude effects
        • polycythemia
    • Mountain
      • sickness
        • with polycythemia , acquired (acute)
    • Polycythemia(secondary)
    • Polycythemia(secondary)
      • acquired
    • Polycythemia(secondary)
      • due to
        • erythropoietin
    • Polycythemia(secondary)
      • due to
        • fall in plasma volume
    • Polycythemia(secondary)
      • due to
        • high altitude
    • Polycythemia(secondary)
      • due to
        • stress
    • Polycythemia(secondary)
      • emotional
    • Polycythemia(secondary)
      • erythropoietin
    • Polycythemia(secondary)
      • Gaisböck's (hypertonica)
    • Polycythemia(secondary)
      • high altitude
    • Polycythemia(secondary)
      • hypertonica
    • Polycythemia(secondary)
      • hypoxemic
    • Polycythemia(secondary)
      • nephrogenous
    • Polycythemia(secondary)
      • relative
    • Polycythemia(secondary)
      • secondary
    • Polycythemia(secondary)
      • spurious
    • Polycythemia(secondary)
      • stress
    • Polycytosis cryptogenica
    • Pseudopolycythemia
    • Sickness
      • mountain
        • acute
    • Stress
      • polycythemia
    • Syndrome
      • Gaisböck's
    • Syndrome
      • hyperviscosity ( of serum)
        • polycythemic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD010
Other specified and unspecified hematologic conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Carotid Body Tumor

    benign paraganglioma at the bifurcation of the common carotid arteries. it can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.

  • Glomus Jugulare Tumor

    a paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. it may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. it is not resectable but radiation therapy is effective. it regresses slowly, but permanent control is regularly achieved. (from dorland, 27th ed; stedman, 25th ed; devita jr et al., cancer: principles & practice of oncology, 3d ed, pp1603-4)

  • Paraganglioma

    a neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). it is more common in women than in men. (stedman, 25th ed; from segen, dictionary of modern medicine, 1992)

  • Paraganglioma, Extra-Adrenal

    a relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the carotid body; glomus jugulare; glomus tympanicum; aortic bodies; and the female genital tract. it consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (from stedman, 27th ed)

  • Carotid Artery, Common

    the two principal arteries supplying the structures of the head and neck. they ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (carotid artery, external) and internal (carotid artery, internal) carotid arteries.

  • Secondary Polycythemia

    polycythemia resulting from an elevated concentration of erythropoietin.

  • Erythrocytosis

    abnormally high level of red blood cells in the blood.

  • Familial Polycythemia|Familial Erythrocytosis

    polycythemia that occurs in groups of related individuals.

  • Stress Polycythemia

    polycythemia that is caused by stress.

  • TEMPI Syndrome

    a rare syndrome characterized by telangiectasias, elevated erythropoietin level and erythrocytosis, monoclonal gammopathy, perinephric fluid collections, and intrapulmonary shunting. it is best classified as a type of plasma cell dyscrasia with paraneoplastic manifestations.

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D75.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
289.0 Secondary polycythemia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D75.1Overview

Is D75.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report secondary polycythemia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D75.1 group to?

When secondary polycythemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D75.1?

Under the General Equivalence Mappings, secondary polycythemia converts to ICD-9-CM 289.0 (secondary polycythemia). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.