2027 ICD-10-CM Diagnosis Code D61.9Aplastic anemia, unspecified

ICD-10-CM Codes›D50–D89›D60-D64›D61

ICD-10-CM D61.9
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D61.9 is a billable ICD-10-CM diagnosis code for aplastic anemia, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 808 through 810. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 110 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Aplastic anemia.

D61.9 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 46 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 46, ESRD (V21) category 46, ESRD (V24) category 46, and RxHCC Part D (V08) category 96 for payment year 2027.

Code Identity

ICD-10-CM Code
D61.9
Billable Status
Yes — Valid for Submission
Code Describes
Aplastic anemia, unspecified
Short Description
Aplastic anemia, unspecified
Same as the full description in the CMS dataset.
Parent Code
D61
Other aplastic anemias and other bone marrow failure syndromes

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD60-D64Aplastic and other anemias and other bone marrow failure syndromes
CategoryD61Other aplastic anemias and other bone marrow failure syndromes
This CodeD61.9Aplastic anemia, unspecified

Medicare Risk Adjustment (HCC)Billing

D61.9 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
Dropped in V28 see all codes that no longer risk-adjust
Prior Model (CMS-HCC V24)
HCC 46
V24 retired last contributed to a Medicare Advantage risk score in payment year 2025
Other CMS Models
PACE (CMS-HCC V22): HCC 46 · ESRD (V21): HCC 46 · ESRD (V24): HCC 46
ESRD V21 weights: 0.180 dialysis, 0.766–1.325 functioning graft · ESRD V24 weights: 0.223 dialysis, 0.748–4.064 functioning graft
Part D (RxHCC)
RxHCC 96 — Acquired Hemolytic, Aplastic, and Sideroblastic Anemias
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Anemia co-occurrent with human immunodeficiency virus infection
  • Anemia in mother complicating pregnancy, childbirth AND/OR puerperium
  • Anemia of endocrine disorder
  • Aplastic anemia
  • Aplastic anemia associated with metabolic alteration
  • Aplastic anemia associated with pancreatitis
  • Aplastic anemia associated with pregnancy
  • Aplastic anemia co-occurrent with human immunodeficiency virus infection
  • Aplastic anemia due to chronic disease
  • Aplastic anemia with AIDS
  • Aplastic bone marrow
  • Aplastic crisis
  • Hematopoietic aplasia
  • Hematopoietic system disease with AIDS
  • Hypocellular bone marrow
  • Hypoplastic anemia
  • Immunologic aplastic anemia
  • Nodular hyperplasia of liver
  • Nodular regenerative hyperplasia of liver
  • Nodule of liver
  • Pulmonary fibrosis, hepatic hyperplasia, bone marrow hypoplasia syndrome
  • Secondary aplastic anemia
  • Thrombocytopenia with AIDS
  • Transient hypoplastic anemia

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D61.9: its own notes plus those printed at D61 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Hypoplastic anemia NOS
  • Medullary hypoplasia

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From D61 Other aplastic anemias and other bone marrow failure syndromes applies to 13 codes
From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D61.9, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming D61.9: they are not reported together with it, unless the two conditions are unrelated.

  • D61.81 Pancytopenia
    pancytopenia (due to) (with) aplastic anemia (D61.9)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD003
Aplastic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Anemia, Aplastic

    a form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Patient EducationClinical

Aplastic Anemia

Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia.

The full article covers:

  • What is aplastic anemia?
  • What causes aplastic anemia?
  • What are the symptoms of aplastic anemia?
  • What other problems can aplastic anemia cause?
  • How is aplastic anemia diagnosed?
  • What are the treatments for aplastic anemia?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D61.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
284.9 Aplastic anemia NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D61.9Overview

What is the ICD-10 code for aplastic anemia, unspecified?

The ICD-10-CM code for aplastic anemia, unspecified is D61.9 (sometimes written as D619). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D61.9 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report aplastic anemia, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D61.9 group to?

When aplastic anemia, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0749 to 2.1706 depending on complications. Higher weights mean higher Medicare reimbursement.

Is D61.9 a CC or MCC?

CMS lists D61.9 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 110 closely related codes in its exclusion list.

What is the ICD-9 equivalent of D61.9?

Under the General Equivalence Mappings, aplastic anemia, unspecified converts to ICD-9-CM 284.9 (aplastic anemia NOS). The mapping is approximate, so confirm the match fits the documentation.

Does D61.9 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage. D61.9 mapped to HCC 46 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 46 (Severe Hematological Disorders), ESRD (V21) category 46 (Severe Hematological Disorders), ESRD (V24) category 46 (Severe Hematological Disorders), and RxHCC Part D (V08) category 96 (Acquired Hemolytic, Aplastic, and Sideroblastic Anemias).