2027 ICD-10-CM Diagnosis Code D44.9Neoplasm of uncertain behavior of unspecified endocrine gland

ICD-10-CM Codes›C00–D49›D37-D48›D44

ICD-10-CM D44.9
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D44.9 is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of unspecified endocrine gland. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. Coders also document this condition as neoplasm of uncertain behavior of endocrine gland. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D44.9
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of uncertain behavior of unspecified endocrine gland
Short Description
Neoplasm of uncertain behavior of unsp endocrine gland
Parent Code
Neoplasm of uncertain behavior of endocrine glands

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD44Neoplasm of uncertain behavior of endocrine glands
This CodeD44.9Neoplasm of uncertain behavior of unspecified endocrine gland

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Neoplasm of uncertain behavior of endocrine gland
  • Neoplasm of uncertain behavior of endocrine glands and nervous system
  • Neoplasm of uncertain behavior of multiple endocrine glands

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D44.9: its own notes plus those printed at D44, block D37-D48, and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From D44 Neoplasm of uncertain behavior of endocrine glands applies to 11 codes
  • multiple endocrine adenomatosis (E31.2-)
  • multiple endocrine neoplasia (E31.2-)
  • neoplasm of uncertain behavior of endocrine pancreas (D37.8)
  • neoplasm of uncertain behavior of ovary (D39.1-)
  • neoplasm of uncertain behavior of testis (D40.1-)
  • neoplasm of uncertain behavior of thymus (D38.4)
From Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes applies to 137 codes
  • neoplasms of unspecified behavior (D49.-)

Notes

General instructions on how these codes are used.

From Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes applies to 137 codes
  • Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made.
From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D44.9, its category, or a range that includes it.

Excludes2 1

These codes carry an Excludes2 note naming D44.9: its condition is not part of those codes, and both may be reported when the patient has both.

  • D49 Neoplasms of unspecified behavior
    neoplasms of uncertain behavior (D37-D44, D48) names D37-D44, which includes this code

Notes 1

These notes mention D44.9.

  • Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
    Categories D37-D44, and D48 classify by site neoplasms of uncertain behavior, i.e., histologic confirmation whether the neoplasm is malignant or benign cannot be made. names D37-D44, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
endocrine gland NECC75.9C79.89D09.3D35.9D44.9D49.7
endocrine gland NEC › pluriglandularC75.8C79.89D09.3D35.7D44.9D49.7
gland, glandular (lymphatic) (system) [See Also: Neoplasm, lymph gland] › endocrine NECC75.9C79.89D09.3D35.9D44.9D49.7
pluriendocrineC75.8C79.89D09.3D35.7D44.9D49.7

Patient EducationClinical

Endocrine Diseases

Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D44.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
237.4 Uncer neo endocrine NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D44.9Overview

What is the ICD-10 code for neoplasm of uncertain behavior of unspecified endocrine gland?

The ICD-10-CM code for neoplasm of uncertain behavior of unspecified endocrine gland is D44.9 (sometimes written as D449). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D44.9 (Neoplasm of uncertain behavior of endocrine glands) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of uncertain behavior of unspecified endocrine gland on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D44.9 group to?

When neoplasm of uncertain behavior of unspecified endocrine gland is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D44.9 be reported with a code from E31.2?

Not as a rule. The Excludes1 note at D44, which applies to D44.9, lists "multiple endocrine adenomatosis (E31.2-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of D44.9?

Under the General Equivalence Mappings, neoplasm of uncertain behavior of unspecified endocrine gland converts to ICD-9-CM 237.4 (uncer neo endocrine NEC). The mapping is approximate, so confirm the match fits the documentation.