ICD-10-CM Code D46.4

Refractory anemia, unspecified

Version 2020 Billable Code

Valid for Submission

D46.4 is a billable code used to specify a medical diagnosis of refractory anemia, unspecified. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D46.4 might also be used to specify conditions or terms like refractory anemia .

ICD-10:D46.4
Short Description:Refractory anemia, unspecified
Long Description:Refractory anemia, unspecified

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D46.4 are found in the index:


Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Refractory anemia

Clinical Information

  • ANEMIA REFRACTORY-. a severe sometimes chronic anemia usually macrocytic in type that does not respond to ordinary antianemic therapy.
  • ANEMIA REFRACTORY WITH EXCESS OF BLASTS-. chronic refractory anemia with granulocytopenia and/or thrombocytopenia. myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells.

Diagnostic Related Groups

The ICD-10 code D46.4 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2020.

  • 811 - RED BLOOD CELL DISORDERS WITH MCC
  • 812 - RED BLOOD CELL DISORDERS WITHOUT MCC

Convert D46.4 to ICD-9

  • 238.72 - Low grde myelody syn les (Approximate Flag)

Code Classification

  • Neoplasms (C00–D48)
    • Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
      • Myelodysplastic syndromes (D46)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Myelodysplastic Syndromes

Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. If you have a myelodysplastic syndrome, the stem cells do not mature into healthy blood cells. Many of them die in the bone marrow. This means that you do not have enough healthy cells, which can lead to infection, anemia, or easy bleeding.

Myelodysplastic syndromes often do not cause early symptoms and are sometimes found during a routine blood test. If you have symptoms, they may include

  • Shortness of breath
  • Weakness or feeling tired
  • Skin that is paler than usual
  • Easy bruising or bleeding
  • Pinpoint spots under the skin caused by bleeding
  • Fever or frequent infections

Myelodysplastic syndromes are rare. People at higher risk are over 60, have had chemotherapy or radiation therapy, or have been exposed to certain chemicals. Treatment options include transfusions, drug therapy, chemotherapy, and blood or bone marrow stem cell transplants.

NIH: National Cancer Institute


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