2027 ICD-10-CM Diagnosis Code Q45.0Agenesis, aplasia and hypoplasia of pancreas
ICD-10-CM Codes›Q00-Q99›Q38-Q45›Q45
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- POA Exempt
- Chronic Condition
Q45.0 is a billable ICD-10-CM diagnosis code for agenesis, aplasia and hypoplasia of pancreas. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 438 through 440. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 6 closely related codes. The code is exempt from POA reporting. Coders also document this condition as agenesis of pancreas. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Digestive congenital anomalies.
Code Identity
Code Classification
Present on Admission (POA)Billing
Q45.0 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Other congenital malformations of the digestive system (Q38-Q45).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Agenesis of pancreas
- Aplasia of pancreas
- Congenital absence of pancreas
- Congenital hypoplasia of gallbladder
- Congenital hypoplasia of pancreas
- Hypoplasia of pancreas, intestinal atresia, hypoplasia of gallbladder syndrome
- Pancreatic agenesis, holoprosencephaly syndrome
- Pancreatic hypoplasia, diabetes mellitus, congenital heart disease syndrome
- Partial pancreatic agenesis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to Q45.0: its own notes plus those printed at Q45 and Chapter 17. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Congenital absence of pancreas
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Notes
General instructions on how these codes are used.
- Codes from this chapter are not for use on maternal records
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Birth Defects
A birth defect is a problem that happens while a baby is developing in the mother's body. Most birth defects happen during the first 3 months of pregnancy. One out of every 33 babies in the United States is born with a birth defect.
The full article covers:
- What are birth defects?
- What causes birth defects?
- Who is at risk of having a baby with birth defects?
- How are birth defects diagnosed?
- What are the treatments for birth defects?
- Can birth defects be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Q45.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Q45.0Overview
What is the ICD-10 code for agenesis, aplasia and hypoplasia of pancreas?
The ICD-10-CM code for agenesis, aplasia and hypoplasia of pancreas is Q45.0 (sometimes written as Q450). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is Q45.0 (Other congenital malformations of digestive system) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report agenesis, aplasia and hypoplasia of pancreas on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does Q45.0 group to?
When agenesis, aplasia and hypoplasia of pancreas is the principal diagnosis on an inpatient stay, it groups to MS-DRG 440, 438, 439, with relative weights from 0.5966 to 1.5763 depending on complications. Higher weights mean higher Medicare reimbursement.
Is Q45.0 a CC or MCC?
CMS lists Q45.0 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 6 closely related codes in its exclusion list.
Is Q45.0 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for agenesis, aplasia and hypoplasia of pancreas on inpatient claims. The code appears in the Other congenital malformations of the digestive system (Q38-Q45) range of the CMS exempt list.
