2027 ICD-10-CM Diagnosis Code P61.2Anemia of prematurity

ICD-10-CM Codes›P00–P96›P50-P61›P61

ICD-10-CM P61.2
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P61.2 is a billable ICD-10-CM diagnosis code for anemia of prematurity. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 91 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemorrhagic and hematologic disorders of newborn.

Code Identity

ICD-10-CM Code
P61.2
Billable Status
Yes — Valid for Submission
Code Describes
Anemia of prematurity
Short Description
Anemia of prematurity
Same as the full description in the CMS dataset.
Parent Code
Other perinatal hematological disorders

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP61Other perinatal hematological disorders
This CodeP61.2Anemia of prematurity

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Anemia of prematurity
  • Megaloblastic anemia due to folate deficiency in prematurity
  • Megaloblastic anemia of premature infant
  • Neonatal anemia

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P61.2: its own notes plus those printed at P61, block P50-P61, and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From P61 Other perinatal hematological disorders applies to 9 codes
  • transient hypogammaglobulinemia of infancy (D80.7)
From Block P50-P61 Hemorrhagic and hematological disorders of newborn applies to 67 codes
  • congenital stenosis and stricture of bile ducts (Q44.3)
  • Crigler-Najjar syndrome (E80.5)
  • Dubin-Johnson syndrome (E80.6)
  • Gilbert syndrome (E80.4)
  • hereditary hemolytic anemias (D55-D58)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P61.2, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming P61.2: they are not reported together with it, unless the two conditions are unrelated.

  • R71 Abnormality of red blood cells
    anemia of premature infant (P61.2)
  • R71 Abnormality of red blood cells
    congenital anemias (P61.2-P61.4)

Excludes2 1

These codes carry an Excludes2 note naming P61.2: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block R70-R79 Abnormal findings on examination of blood, without diagnosis
    hemorrhagic and hematological disorders of newborn (P50-P61) names P50-P61, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL011
Hemorrhagic and hematologic disorders of newborn
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Anemia of Prematurity

    a blood disorder characterized by low hemoglobin levels in premature neonates that usually spontaneously resolves within 3-6 months post birth. a combination of factors including the transition from the liver to the bone marrow for erythropoiesis in a neonate, blood loss experienced during delivery, the shortened life span of fetal blood cells, and an acclimation to a relatively hyperoxic environment outside the womb can predispose a neonate to this condition.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P61.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
776.6 Anemia of prematurity
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P61.2Overview

What is the ICD-10 code for anemia of prematurity?

The ICD-10-CM code for anemia of prematurity is P61.2 (sometimes written as P612). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P61.2 (Other perinatal hematological disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report anemia of prematurity on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P61.2 group to?

When anemia of prematurity is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is P61.2 a CC or MCC?

CMS lists P61.2 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 91 closely related codes in its exclusion list.

Can P61.2 be reported with D80.7?

Not as a rule. The Excludes1 note at P61, which applies to P61.2, lists "transient hypogammaglobulinemia of infancy (D80.7)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).