Kernicterus (P57) ICD-10-CM
The P57 code range covers kernicterus with 4 ICD-10-CM diagnosis codes. 3 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the P57 Range 4 codes · 3 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the P57 range.
Kernicterus
A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
About the P57 Code Range
ICD-10 code P57 and its subcategories are used specifically to document kernicterus, a serious condition caused by high levels of bilirubin affecting a newborn’s brain. These codes guide healthcare providers and coders in identifying different types and causes of kernicterus for accurate clinical records and billing.
Kernicterus, sometimes called acute or chronic bilirubin encephalopathy or simply kernicterus of newborn, is captured under P57. If the kernicterus arises due to immune-related destruction of red blood cells, such as from isoimmunization between mother and infant, it is coded as P57.0. Other specific but less common forms fall under P57.8, while P57.9 is used whenever the exact cause is not detailed. These codes help differentiate between underlying mechanisms like hemolytic jaundice and clarify the newborn’s condition, enabling precise documentation and appropriate care.
Questions About This Page
How many billable codes are in the P57 range?
Of the 4 codes in this range, 3 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the P57 range classify?
The range classifies kernicterus. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
