Kernicterus (P57) ICD-10-CM
The P57 code range covers kernicterus with 4 ICD-10-CM diagnosis codes. 3 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Codes in the P57 Range 4 codes · 3 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the P57 range.
Kernicterus
A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
Kernicterus Related to Isoimmunization
Encephalopathy in infants due to high levels of unconjugated bilirubin that are a result of Rh incompatibility between the mother and the fetus.
About the P57 Code Range
Kernicterus primarily affects newborns and involves bilirubin entering the brain, where it acts as a toxin.
The subdivisions distinguish kernicterus due to isoimmunization (P57.0), other specified kernicterus (P57.8), and kernicterus without a specified type (P57.9).
Questions About This Page
How many billable codes are in the P57 range?
Of the 4 codes in this range, 3 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the P57 range classify?
The range classifies kernicterus. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.