2026 ICD-10-CM Diagnosis Code P58.42Neonatal jaundice due to drugs or toxins given to newborn

ICD-10-CM Codes›P00–P96›P50-P61›P58

ICD-10-CM P58.42
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P58.42 is a billable ICD-10-CM diagnosis code for neonatal jaundice due to drugs or toxins given to newborn. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Hemolytic jaundice and perinatal jaundice.

Code Identity

ICD-10-CM Code
P58.42
Billable Status
Yes — Valid for Submission
Code Describes
Neonatal jaundice due to drugs or toxins given to newborn
Short Description
Neonatal jaundice due to drugs or toxins given to newborn
Same as the full description in the CMS dataset.
Parent Code
P58.4
Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP58Neonatal jaundice due to other excessive hemolysis
This CodeP58.42Neonatal jaundice due to drugs or toxins given to newborn

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Jaundice(yellow)
      • newborn
        • due to or associated with
          • drugs or toxins
            • given to newborn
    • Jaundice(yellow)
      • newborn
        • due to or associated with
          • excessive hemolysis
            • due to
              • drugs or toxins
                • given to newborn

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR PNL007
Hemolytic jaundice and perinatal jaundice
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Jaundice

Jaundice causes your skin and the whites of your eyes to turn yellow. Too much bilirubin causes jaundice. Bilirubin is a yellow chemical in hemoglobin, the substance that carries oxygen in your red blood cells. As red blood cells break down, your body builds new cells to replace them. The old ones are processed by the liver.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P58.42 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
774.1 Perinat jaund:hemolysis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P58.42Overview

Is P58.42 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neonatal jaundice due to drugs or toxins given to newborn on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of P58.42?

Under the General Equivalence Mappings, neonatal jaundice due to drugs or toxins given to newborn converts to ICD-9-CM 774.1 (perinat jaund:hemolysis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.