2026 ICD-10-CM Diagnosis Code L12.31Epidermolysis bullosa due to drug

ICD-10-CM CodesL00–L99L10-L14L12

ICD-10-CM L12.31
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

L12.31 is a billable ICD-10-CM diagnosis code for epidermolysis bullosa due to drug. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 595 through 596. Coders also document this condition as acquired epidermolysis bullosa. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified inflammatory condition of skin.

Code Identity

ICD-10-CM Code
L12.31
Billable Status
Yes — Valid for Submission
Code Describes
Epidermolysis bullosa due to drug
Short Description
Epidermolysis bullosa due to drug
Same as the full description in the CMS dataset.
Parent Code
Acquired epidermolysis bullosa

Code Classification

ChapterL00–L99Diseases of the skin and subcutaneous tissue
SectionL10-L14Bullous disorders
CategoryL12Pemphigoid
This CodeL12.31Epidermolysis bullosa due to drug

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired epidermolysis bullosa
  • Autoimmune bullous dermatosis due to drug
  • Bullous dermatosis precipitated by drug treatment
  • Drug-induced epidermolysis bullosa acquisita
  • Epidermal fragility

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Use Additional Code

  • code for adverse effect, if applicable, to identify drug T36 T50

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Epidermolysis
      • bullosa (congenital)
        • acquired
          • drug-induced

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SKN002
Other specified inflammatory condition of skin
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Skin Conditions

Your skin is your body's largest organ. It covers the entire outside of your body. There are many ways that your skin protects your body and helps keep you healthy. For example, it:

The full article covers:

  • What does your skin do?
  • What problems and conditions can affect your skin?
  • How can I keep my skin healthy?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert L12.31 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
695.15 Toxic epidrml necrolysis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About L12.31Overview

Is L12.31 (Acquired epidermolysis bullosa) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report epidermolysis bullosa due to drug on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does L12.31 group to?

When epidermolysis bullosa due to drug is the principal diagnosis on an inpatient stay, it groups to MS-DRG 595, 596, with relative weights from 1.0825 to 2.1207 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of L12.31?

Under the General Equivalence Mappings, epidermolysis bullosa due to drug converts to ICD-9-CM 695.15 (toxic epidrml necrolysis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.