2026 ICD-10-CM Diagnosis Code L12Pemphigoid
L12 is a non-billable ICD-10-CM category code for pemphigoid, so it cannot be submitted on claims. Use a more specific code from this category instead, such as L12.0, L12.1, L12.2, and L12.30.
Code Identity
Code Classification
Specific Coding for PemphigoidOverview
Non-specific codes like L12 require more characters. Use one of these billable codes instead:
Use L12.0 for Bullous pemphigoid
Use L12.1 for Cicatricial pemphigoid
Use L12.2 for Chronic bullous disease of childhood
L12.3 for Acquired epidermolysis bullosa
Use L12.30 for Acquired epidermolysis bullosa, unspecified
Use L12.31 for Epidermolysis bullosa due to drug
Use L12.35 for Other acquired epidermolysis bullosa
Use L12.8 for Other pemphigoid
Use L12.9 for Pemphigoid, unspecified
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Clinical InformationClinical
Benign Mucous Membrane Pemphigoid
a chronic autoimmune disorder characterized by the development of blisters and ulcers in mucous membranes. it affects most often the gums, eyelids and genital mucosa sites.Bullous Pemphigoid
an autoimmune chronic skin disorder characterized by the presence of large blisters. it usually affects elderly people and tends to subside spontaneously.COL17A1 wt Allele|BA16H23.2|BA16H23.2 (Collagen, Type XVII, Alpha 1 (BP180)) Gene|BP180|BPA-2|BPAG2|Bullous Pemphigoid Antigen 2 (180kD) Gene|Collagen Type XVII Alpha 1 Chain wt Allele|Collagen, Type XVII, Alpha 1 Gene|Collagen, Type XVII, Alpha-1 Gene|ERED|LAD-1
human col17a1 wild-type allele is located in the vicinity of 10q25.1 and is approximately 55 kb in length. this allele, which encodes collagen alpha-1(xvii) chain protein, is involved in hemidesmosome formation and keratinocyte adhesion. mutation of the gene and immunoreactivity during revertant mosaicism is associated with both generalized atrophic benign and junctional epidermolysis bullosa. mutations in the gene are also associated with epithelial recurrent erosion dystrophy.Collagen Alpha-1(XVII) Chain|180 kDa Bullous Pemphigoid Antigen 2|Alpha 1 Type XVII Collagen|Bullous Pemphigoid Antigen 2|COL17A1|Collagen Type XVII Alpha 1 Chain|Collagen Type XVII Alpha 1 Polypeptide|Type XVII Collagen Alpha-1
collagen alpha-1(xvii) chain (1497 aa, ~150 kda) is encoded by the human col17a1 gene. this protein plays a role in the attachment of keratinocytes to the basement membrane.Dystonin|230 kDa Bullous Pemphigoid Antigen|230/240 kDa Bullous Pemphigoid Antigen|Bullous Pemphigoid Antigen|Bullous Pemphigoid Antigen 1|Bullous Pemphigoid Antigen 1, 230/240kDa|DST|Dystonia Musculorum Protein|Hemidesmosomal Plaque Protein|Trabeculin-Beta
dystonin (7570 aa, ~860 kda) is encoded by the human dst gene. this protein plays a structural role in cytoskeleton networks.Ocular Cicatricial Pemphigoid
a chronic autoimmune disorder that belongs to the mucous membrane pemphigoid disorders. it is characterized by bilateral scarring and opacification of the conjunctivae. it presents with pain and burning sensation in the eyes and photophobia. it leads to blindness.Pemphigoid
a rare autoimmune blistering skin disorder that resembles pemphigus but is histologically and clinically distinguishable by lack of evidence of acantholysis and a generally benign course.Pemphigoid Antibody Measurement|PEMAB|Pemphigoid Antibodies|Pemphigoid Antibodies
the determination of the amount of pemphigoid antibodies present in a sample.Pemphigoid Gestationis|Gestational Pemphigoid|Gestational Pemphigoid|Herpes Gestationis
an autoimmune bullous dermatitis that develops during pregnancy, most often during the second and third trimesters.Collagen Alpha-1(XVII) Chain|180 kDa Bullous Pemphigoid Antigen 2|Alpha 1 Type XVII Collagen|BASEMENT MEMBRANE ZONE BP180|BMZ BP180|BP180|BPAG2|Bullous Pemphigoid Antigen 2|Bullous Pemphigoid Antigen 2|COL17A1|Collagen Type XVII Alpha 1 Chain|Collagen Type XVII Alpha 1 Chain|Collagen Type XVII Alpha 1 Polypeptide|Type XVII Collagen Alpha-1
collagen alpha-1(xvii) chain (1497 aa, ~150 kda) is encoded by the human col17a1 gene. this protein plays a role in the attachment of keratinocytes to the basement membrane.Dystonin|230 kDa Bullous Pemphigoid Antigen|230/240 kDa Bullous Pemphigoid Antigen|BASEMENT MEMBRANE ZONE BP230|BMZ BP230|BP230|BPAG1|Bullous Pemphigoid Antigen|Bullous Pemphigoid Antigen 1|Bullous Pemphigoid Antigen 1|Bullous Pemphigoid Antigen 1, 230/240kDa|DST|Dystonia Musculorum Protein|Hemidesmosomal Plaque Protein|Trabeculin-Beta
dystonin (7570 aa, ~860 kda) is encoded by the human dst gene. this protein plays a structural role in cytoskeleton networks.Pemphigoid Antibody Measurement
the determination of the amount of pemphigoid antibodies present in a sample.Pemphigoid Autoantigens|PEMPHIGOID AUTOANTIGENS
a group of autoimmune substances related to the pemphigoid diseases that may be mainly comprised of (but not limited to) the basement membrane zone antigens and proteins from the collagen superfamily.
Patient EducationClinical
Pemphigus
Pemphigus is an autoimmune disorder. If you have it, your immune system attacks healthy cells in your skin and mouth, causing blisters and sores. No one knows the cause. Pemphigus does not spread from person to person. It does not appear to be inherited. But some people's genes put them more at risk for pemphigus.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
