2026 ICD-10-CM Diagnosis Code Q81Epidermolysis bullosa

ICD-10-CM Codes›Q00-Q99›Q80-Q89›Q81

ICD-10-CM Q81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q81 is a non-billable ICD-10-CM category code for epidermolysis bullosa, so it cannot be submitted on claims. Use a more specific code from this category instead, such as Q81.0, Q81.1, Q81.2, and Q81.8.

Code Identity

ICD-10-CM Code
Q81
Billable Status
No — Non-Billable Category
Code Describes
Epidermolysis bullosa
Chapter
Q80-Q89
Other congenital malformations

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ80-Q89Other congenital malformations
CategoryQ81Epidermolysis bullosa
This CodeQ81Epidermolysis bullosa

Specific Coding for Epidermolysis bullosaOverview

Non-specific codes like Q81 require more characters. Use one of these billable codes instead:

  • Use Q81.0 for Epidermolysis bullosa simplex

  • Use Q81.1 for Epidermolysis bullosa letalis

  • Use Q81.2 for Epidermolysis bullosa dystrophica

  • Use Q81.8 for Other epidermolysis bullosa

  • Use Q81.9 for Epidermolysis bullosa, unspecified

Clinical InformationClinical

  • Epidermolysis Bullosa

    group of genetically determined disorders characterized by the blistering of skin and mucosae. there are four major forms: acquired, simple, junctional, and dystrophic. each of the latter three has several varieties.

  • Epidermolysis Bullosa Acquisita

    form of epidermolysis bullosa characterized by trauma-induced, subepidermal blistering with no family history of the disease. direct immunofluorescence shows immunoglobulin g deposited at the dermo-epidermal junction.

  • Epidermolysis Bullosa Dystrophica

    form of epidermolysis bullosa characterized by atrophy of blistered areas, severe scarring, and nail changes. it is most often present at birth or in early infancy and occurs in both autosomal dominant and recessive forms. all forms of dystrophic epidermolysis bullosa result from mutations in collagen type vii, a major component fibrils of basement membrane and epidermis.

  • Epidermolysis Bullosa Simplex

    a form of epidermolysis bullosa characterized by serous bullae that heal without scarring. mutations in the genes that encode keratin-5 and keratin-14 have been associated with several subtypes of epidermolysis bullosa simplex.

  • Epidermolysis Bullosa, Junctional

    form of epidermolysis bullosa having onset at birth or during the neonatal period and transmitted through autosomal recessive inheritance. it is characterized by generalized blister formation, extensive denudation, and separation and cleavage of the basal cell plasma membranes from the basement membrane.

Patient EducationClinical

Skin Conditions

Your skin is your body's largest organ. It covers the entire outside of your body. There are many ways that your skin protects your body and helps keep you healthy. For example, it:

The full article covers:

  • What does your skin do?
  • What problems and conditions can affect your skin?
  • How can I keep my skin healthy?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Q81Overview

Is Q81 (Epidermolysis bullosa) a billable code?

No. This is a category header that groups the codes for epidermolysis bullosa, and headers cannot be submitted on claims. Claims for epidermolysis bullosa need a more specific code from this category, such as Q81.0, Q81.1, and Q81.2.