2026 ICD-10-CM Diagnosis Code E87.5Hyperkalemia

ICD-10-CM Codes›E00–E89›E70-E88›E87

ICD-10-CM E87.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E87.5 is a billable ICD-10-CM diagnosis code for hyperkalemia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Fluid and electrolyte disorders.

Code Identity

ICD-10-CM Code
E87.5
Billable Status
Yes — Valid for Submission
Code Describes
Hyperkalemia
Short Description
Hyperkalemia
Same as the full description in the CMS dataset.
Parent Code
E87
Other disorders of fluid, electrolyte and acid-base balance

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE87Other disorders of fluid, electrolyte and acid-base balance
This CodeE87.5Hyperkalemia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute hyperkalemia
  • Chronic hyperkalemia
  • Drug-induced hyperkalemia
  • Hyperkalemia
  • Hyperkalemia caused by angiotensin-converting enzyme inhibitor
  • Hyperkalemia with normal acid-base balance
  • Hyperkalemia, diminished renal excretion
  • Hyperkalemia, transcellular shifts
  • Hyperkalemic acidosis
  • Hyperkalemic alkalosis
  • Potassium level - finding
  • Potassium overload
  • Serum potassium level above reference range

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Potassium K excess
  • Potassium K overload

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Excess, excessive, excessively
      • kalium
    • Excess, excessive, excessively
      • potassium (K)
    • Findings, abnormal, inconclusive, without diagnosis
      • potassium (deficiency)
        • excess
    • Hyperkalemia
    • Hyperpotassemia
    • Intoxication
      • potassium (K)
    • Overload
      • potassium (K)
    • Syndrome
      • hyperkalemic
    • Syndrome
      • potassium intoxication

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END011
Fluid and electrolyte disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hyperkalemia

    abnormally high potassium concentration in the blood, most often due to defective renal excretion. it is characterized clinically by electrocardiographic abnormalities (elevated t waves and depressed p waves, and eventually by atrial asystole). in severe cases, weakness and flaccid paralysis may occur. (dorland, 27th ed)

  • Pseudohypoaldosteronism

    a heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. congenital forms are rare autosomal disorders characterized by neonatal hypertension, hyperkalemia, increased renin activity and aldosterone concentration. the type i features hyperkalemia with sodium wasting; type ii, hyperkalemia without sodium wasting. pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after kidney transplantation.

  • Grade 1 Hyperkalemia, CTCAE|Grade 1 Hyperkalemia

    >uln - 5.5 mmol/l

  • Grade 2 Hyperkalemia, CTCAE|Grade 2 Hyperkalemia

    >5.5 - 6.0 mmol/l; intervention initiated

  • Grade 3 Hyperkalemia, CTCAE|Grade 3 Hyperkalemia

    >6.0 - 7.0 mmol/l; hospitalization indicated

  • Grade 1 Hyperkalemia, CTCAE|Grade 1 Hyperkalemia

    >uln-5.5 mmol/l

  • Grade 2 Hyperkalemia, CTCAE|Grade 2 Hyperkalemia

    >5.5-6.0 mmol/l; intervention initiated

  • Grade 3 Hyperkalemia, CTCAE|Grade 3 Hyperkalemia

    >6.0-7.0 mmol/l; hospitalization indicated

  • Grade 4 Hyperkalemia, CTCAE|Grade 4 Hyperkalemia

    >7.0 mmol/l; life-threatening consequences

  • Grade 5 Hyperkalemia, CTCAE|Grade 5 Hyperkalemia

    death

  • Hyperkalemia

    higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs.

  • Hyperkalemia, CTCAE|Hyperkalemia|Hyperkalemia

    a disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs.

  • Hyperkalemic Mineralocorticoid Resistance|Chloride Shunt Syndrome|Familial Hyperkalemic Hypertension|Gordon Hyperkalemia|Mineralocorticoid Resistant Hyperkalemia|PHA Type 2|Pseudohypoaldosteronism, Type II|Spitzer-Weinstein Syndrome

    a genetically heterogynous condition characterized by hyperkalemia, hyperchloremic acidosis, low or suppressed renin activity, and normal to high concentrations of aldosterone. mutations in genes (for example wnk1 or wnk4), regulating na-cl cotransporters (ncc), na-k-cl cotransporters (nkcc2), or the renal outer medullary potassium (romk) channel have been identified as causative in this condition. the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid.

  • Hyperkalemic Mineralocorticoid Resistance|Chloride Shunt Syndrome|Familial Hyperkalemic Hypertension|Gordon Hyperkalemia|Mineralocorticoid Resistant Hyperkalemia|PHA Type 2|Pseudohypoaldosteronism, Type II|Spitzer-Weinstein Syndrome

    a genetically heterogenous condition characterized by hyperkalemia, hyperchloremic acidosis, low or suppressed renin activity, and normal to high concentrations of aldosterone. mutations in genes (for example wnk1 or wnk4), regulating na-cl cotransporters (ncc), na-k-cl cotransporters (nkcc2), or the renal outer medullary potassium (romk) channel have been identified as causative in this condition. the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid.

Patient EducationClinical

Fluid and Electrolyte Balance

Electrolytes are minerals that have an electric charge when they are dissolved in water or body fluids, including blood. The electric charge can be positive or negative. You have electrolytes in your blood, urine (pee), tissues, and other body fluids.

The full article covers:

  • What are electrolytes?
  • What are the different types of electrolytes in your body?
  • What is an electrolyte imbalance?
  • What are the different types of electrolyte imbalances?
  • How are electrolyte imbalances diagnosed?
  • What are the treatments for electrolyte imbalances?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E87.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
276.7 Hyperpotassemia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E87.5Overview

Is E87.5 (Other disorders of fluid, electrolyte and acid-base balance) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hyperkalemia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E87.5 group to?

When hyperkalemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E87.5?

Under the General Equivalence Mappings, hyperkalemia converts to ICD-9-CM 276.7 (hyperpotassemia). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.