2026 ICD-10-CM Diagnosis Code E87.3Alkalosis

ICD-10-CM Codes›E00–E89›E70-E88›E87

ICD-10-CM E87.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E87.3 is a billable ICD-10-CM diagnosis code for alkalosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Fluid and electrolyte disorders.

Code Identity

ICD-10-CM Code
E87.3
Billable Status
Yes — Valid for Submission
Code Describes
Alkalosis
Short Description
Alkalosis
Same as the full description in the CMS dataset.
Parent Code
E87
Other disorders of fluid, electrolyte and acid-base balance

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE87Other disorders of fluid, electrolyte and acid-base balance
This CodeE87.3Alkalosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute respiratory alkalosis
  • Alkalemia
  • Alkalosis
  • Altitude alkalosis
  • Chloride non-responsive metabolic alkalosis
  • Chloride responsive metabolic alkalosis
  • Chronic respiratory alkalosis
  • Compensated alkalosis
  • Compensated metabolic alkalosis
  • Compensated respiratory alkalosis
  • Familial hypokalemic alkalosis, Gullner type
  • Hyperkalemia
  • Hyperkalemic alkalosis
  • Hyperuricemia, pulmonary hypertension, renal failure, alkalosis syndrome
  • Hypochloremic alkalosis
  • Hypokalemic alkalosis
  • Hypokalemic alkalosis due to diarrhea
  • Metabolic alkalemia
  • Metabolic alkalosis
  • Mixed acid-base balance disorder
  • Mixed acid-base balance disorders - not compensated primary disorder
  • Respiratory alkalemia
  • Respiratory alkalosis
  • Respiratory alkalosis and metabolic alkalosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Alkalosis NOS
  • Metabolic alkalosis
  • Respiratory alkalosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Acapnia
    • Alkalemia
    • Alkalosis
    • Alkalosis
      • metabolic
    • Alkalosis
      • respiratory
    • Disorder(of)
      • electrolyte (balance) NEC
        • alkalosis (metabolic) (respiratory)
    • Tetany(due to)
      • alkalosis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END011
Fluid and electrolyte disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Alkalosis

    a pathological condition that removes acid or adds base to the body fluids.

  • Alkalosis, Respiratory

    a state due to excess loss of carbon dioxide from the body. (dorland, 27th ed)

  • Hyperkalemia

    abnormally high potassium concentration in the blood, most often due to defective renal excretion. it is characterized clinically by electrocardiographic abnormalities (elevated t waves and depressed p waves, and eventually by atrial asystole). in severe cases, weakness and flaccid paralysis may occur. (dorland, 27th ed)

  • Pseudohypoaldosteronism

    a heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. congenital forms are rare autosomal disorders characterized by neonatal hypertension, hyperkalemia, increased renin activity and aldosterone concentration. the type i features hyperkalemia with sodium wasting; type ii, hyperkalemia without sodium wasting. pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after kidney transplantation.

  • Compensated Metabolic Acidosis|Compensated metabolic alkalosis

    the presence of metabolic acidosis despite a nearly normal ph due to a physiologic respiratory compensatory response that lowers the partial pressure of carbon dioxide (paco2) by inducing hyperventilation.

  • Alkalosis

    an abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues.

  • Alkalosis, CTCAE|Alkalosis|Alkalosis

    a disorder characterized by abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues.

  • Bartter Syndrome, Type 1|BARTS1|Hyperprostaglandin E Syndrome 1|Hypokalemic Alkalosis with Hypercalciuria 1, Antenatal|Type 1 Bartter Syndrome

    an autosomal recessive subtype of bartter syndrome caused by mutation(s) in the slc12a1 gene, encoding solute carrier family 12 member 1.the onset occurs in the antenatal period, and may be characterized by polyhydramnios, premature birth, failure to thrive and mental retardation. clinical variability in the severity of symptoms exists and an essential feature of antenatal forms of bartter syndrome is marked hypercalciuria.

  • Bartter Syndrome|Bartter's Syndrome|Hypokalemic Alkalosis

    a rare inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. patients have high levels of plasma renin concentration which is not associated with hypertension.

  • Grade 1 Alkalosis, CTCAE|Grade 1 Alkalosis

    ph >normal, but <=7.5

  • Grade 3 Alkalosis, CTCAE|Grade 3 Alkalosis

    ph >7.5

  • Grade 4 Alkalosis, CTCAE|Grade 4 Alkalosis

    life-threatening consequences

  • Grade 5 Alkalosis, CTCAE|Grade 5 Alkalosis

    death

  • Metabolic Alkalosis

    abnormally increased ph levels in the blood due to excessive loss of acid and/or accumulation of base.

  • Respiratory Alkalosis

    a condition in which the blood ph is greater than normal, secondary to impaired gas exchange.

  • WDHA Syndrome|Islet Cell WDHA Syndrome|Pancreatic Cholera|Pancreatic WDHA Syndrome|Verner Morrison Syndrome|WDHH|Watery Diarrhea Syndrome|Watery Diarrhea with Hypokalemic Alkalosis|Watery Diarrhea, Hypokalemia, and Achlorhydria Syndrome

    a rare syndrome characterized by severe watery diarrhea, hypokalemia, and achlorhydria. it is caused by the oversecretion of vasoactive intestinal peptide from the pancreatic islet cells.

  • Grade 1 Hyperkalemia, CTCAE|Grade 1 Hyperkalemia

    >uln-5.5 mmol/l

  • Grade 2 Hyperkalemia, CTCAE|Grade 2 Hyperkalemia

    >5.5-6.0 mmol/l; intervention initiated

  • Grade 3 Hyperkalemia, CTCAE|Grade 3 Hyperkalemia

    >6.0-7.0 mmol/l; hospitalization indicated

  • Grade 4 Hyperkalemia, CTCAE|Grade 4 Hyperkalemia

    >7.0 mmol/l; life-threatening consequences

  • Grade 5 Hyperkalemia, CTCAE|Grade 5 Hyperkalemia

    death

  • Hyperkalemia

    higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs.

  • Hyperkalemia, CTCAE|Hyperkalemia|Hyperkalemia

    a disorder characterized by laboratory test results that indicate an elevation in the concentration of potassium in the blood; associated with kidney failure or sometimes with the use of diuretic drugs.

  • Hyperkalemic Mineralocorticoid Resistance|Chloride Shunt Syndrome|Familial Hyperkalemic Hypertension|Gordon Hyperkalemia|Mineralocorticoid Resistant Hyperkalemia|PHA Type 2|Pseudohypoaldosteronism, Type II|Spitzer-Weinstein Syndrome

    a genetically heterogynous condition characterized by hyperkalemia, hyperchloremic acidosis, low or suppressed renin activity, and normal to high concentrations of aldosterone. mutations in genes (for example wnk1 or wnk4), regulating na-cl cotransporters (ncc), na-k-cl cotransporters (nkcc2), or the renal outer medullary potassium (romk) channel have been identified as causative in this condition. the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid.

  • Hyperkalemic Mineralocorticoid Resistance|Chloride Shunt Syndrome|Familial Hyperkalemic Hypertension|Gordon Hyperkalemia|Mineralocorticoid Resistant Hyperkalemia|PHA Type 2|Pseudohypoaldosteronism, Type II|Spitzer-Weinstein Syndrome

    a genetically heterogenous condition characterized by hyperkalemia, hyperchloremic acidosis, low or suppressed renin activity, and normal to high concentrations of aldosterone. mutations in genes (for example wnk1 or wnk4), regulating na-cl cotransporters (ncc), na-k-cl cotransporters (nkcc2), or the renal outer medullary potassium (romk) channel have been identified as causative in this condition. the primary abnormality is thought to be a specific defect of the renal secretory mechanism for potassium, which limits the kaliuretic response to, but not the sodium and chloride reabsorptive effect of, mineralocorticoid.

  • Grade 1 Hyperkalemia, CTCAE|Grade 1 Hyperkalemia

    >uln - 5.5 mmol/l

  • Grade 2 Hyperkalemia, CTCAE|Grade 2 Hyperkalemia

    >5.5 - 6.0 mmol/l; intervention initiated

  • Grade 3 Hyperkalemia, CTCAE|Grade 3 Hyperkalemia

    >6.0 - 7.0 mmol/l; hospitalization indicated

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E87.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
276.3 Alkalosis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E87.3Overview

Is E87.3 (Other disorders of fluid, electrolyte and acid-base balance) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report alkalosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E87.3 group to?

When alkalosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E87.3?

Under the General Equivalence Mappings, alkalosis converts to ICD-9-CM 276.3 (alkalosis). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.