2026 ICD-10-CM Diagnosis Code E87.29Other acidosis

ICD-10-CM Codes›E00–E89›E70-E88›E87

ICD-10-CM E87.29
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E87.29 is a billable ICD-10-CM diagnosis code for other acidosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Fluid and electrolyte disorders.

Code Identity

ICD-10-CM Code
E87.29
Billable Status
Yes — Valid for Submission
Code Describes
Other acidosis
Short Description
Other acidosis
Same as the full description in the CMS dataset.
Parent Code
E87.2
Acidosis

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE87Other disorders of fluid, electrolyte and acid-base balance
This CodeE87.29Other acidosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chorea due to inherited organic acidemia
  • Chorea due to metabolic disorder
  • Compensated acidosis
  • Compensated respiratory acidosis
  • Ketoacidosis
  • Ketoacidosis due to acute alcohol intoxication
  • Ketoacidosis due to monocarboxylate transporter-1 deficiency
  • Respiratory acidemia
  • Respiratory acidosis
  • Starvation
  • Starvation ketoacidosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Respiratory acidosis NOS

Type 2 Excludes

  • acute respiratory acidosis J96.02
  • chronic respiratory acidosis J96.12

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Acarbia
    • Acid
      • intoxication
    • Acidosis(lactic)
      • respiratory
    • Acidosis(lactic)
      • specified NEC
    • Disorder(of)
      • electrolyte (balance) NEC
        • acidosis (lactic) (metabolic)
          • respiratory
    • Disorder(of)
      • electrolyte (balance) NEC
        • acidosis (lactic) (metabolic)
          • specified NEC
    • Intoxication
      • acid
    • Ketoacidosis
    • Kussmaul's
      • respiration
    • Retention
      • carbon dioxide

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END011
Fluid and electrolyte disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Acidosis

    a pathologic condition of acid accumulation or depletion of base in the body. the two main types are respiratory acidosis and metabolic acidosis, due to metabolic acid build up.

  • Acidosis, Lactic

    acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. it may occur spontaneously or in association with diseases such as diabetes mellitus; leukemia; or liver failure.

  • Acidosis, Renal Tubular

    a group of genetic disorders of the kidney tubules characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic acidosis. defective renal acidification of urine (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as hypokalemia, hypercalcinuria with nephrolithiasis and nephrocalcinosis, and rickets.

  • Acidosis, Respiratory

    respiratory retention of carbon dioxide. it may be chronic or acute.

  • Diabetic Ketoacidosis

    a life-threatening complication of diabetes mellitus, primarily of type 1 diabetes mellitus with severe insulin deficiency and extreme hyperglycemia. it is characterized by ketosis; dehydration; and depressed consciousness leading to coma.

  • Hypoaldosteronism

    a congenital or acquired condition of insufficient production of aldosterone by the adrenal cortex leading to diminished aldosterone-mediated synthesis of na(+)-k(+)-exchanging atpase in renal tubular cells. clinical symptoms include hyperkalemia, sodium-wasting, hypotension, and sometimes metabolic acidosis.

  • Starvation

    lengthy and continuous deprivation of food. (stedman, 25th ed)

  • Compensated Metabolic Acidosis|Compensated metabolic alkalosis

    the presence of metabolic acidosis despite a nearly normal ph due to a physiologic respiratory compensatory response that lowers the partial pressure of carbon dioxide (paco2) by inducing hyperventilation.

  • Diabetic Ketoacidosis|DKA|DKA|Elevated ketones/Diabetic Ketoacidosis

    the metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

  • Hyperchloremic Acidosis|Metabolic acidosis, normal anion gap, bicarbonate losses

    metabolic acidosis with a normal serum ratio of anions to cations and replacement of bicarbonate with chloride.

  • Acidosis

    an abnormally high acidity of the blood and other body tissues. acidosis can be either respiratory or metabolic.

  • Acidosis

    an abnormally high acidity (excess hydrogen-ion concentration) of the blood and other body tissues.

  • Acidosis, CTCAE|Acidosis|Acidosis

    a disorder characterized by abnormally high acidity (high hydrogen-ion concentration) of the blood and other body tissues.

  • Autosomal Recessive Distal Renal Tubular Acidosis-4 with Hemolytic Anemia|DRTA4

    an autosomal recessive type of distal renal tubular acidosis caused by mutation(s) in the slc4a1 gene, encoding band 3 anion transport protein. additionally, it may be characterized by hemolytic anemia.

  • Diabetes Mellitus due to Underlying Condition with Ketoacidosis with Coma|Diabetes mellitus due to underlying condition with ketoacidosis with coma

    evidence of diabetes mellitus due to underlying condition with ketoacidosis with coma.

  • Diabetes Mellitus due to Underlying Condition with Ketoacidosis without Coma|Diabetes mellitus due to underlying condition with ketoacidosis without coma

    evidence of diabetes mellitus due to underlying condition with ketoacidosis without coma.

  • Diabetic Ketoacidosis|DKA|DKA|Elevated Ketones/Diabetic Ketoacidosis

    the metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

  • Distal Renal Tubular Acidosis

    failure of the renal tubules of the kidney to excrete urine of sufficient acidity, resulting in metabolic acidosis.

  • Drug or Chemical Induced Diabetes Mellitus with Ketoacidosis with Coma|Drug or chemical induced diabetes mellitus with ketoacidosis with coma

    evidence of drug or chemical induced diabetes mellitus with ketoacidosis with coma.

  • Drug or Chemical Induced Diabetes Mellitus with Ketoacidosis without Coma|Drug or chemical induced diabetes mellitus with ketoacidosis without coma

    evidence of drug or chemical induced diabetes mellitus with ketoacidosis without coma.

  • Fetal Acidosis|Fetal Acidemia|Fetal Acidemia

    an abnormally high hydrogen ion concentration (umbilical arterial blood ph less than 7.00) in fetal blood or tissue.

  • Grade 1 Acidosis, CTCAE|Grade 1 Acidosis

    ph =7.3

  • Grade 3 Acidosis, CTCAE|Grade 3 Acidosis

    ph <7.3

  • Grade 4 Acidosis, CTCAE|Grade 4 Acidosis

    life-threatening consequences

  • Grade 5 Acidosis, CTCAE|Grade 5 Acidosis

    death

  • Lactic Acidosis

    metabolic acidosis characterized by the accumulation of lactate in the body. it is caused by tissue hypoxia.

  • MELAS Syndrome|MELAS|Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke

    a rare progressive neurodegenerative disorder characterized by mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.

  • Metabolic Acidosis|Acidosis|metabolic acidosis

    increased acidity in the blood secondary to acid base imbalance. causes include diabetes, kidney failure and shock.

  • Osteopetrosis with Renal Tubular Acidosis|Autosomal Recessive Osteopetrosis 3|Autosomal Recessive Osteopetrosis, Type 3|Carbonic Anhydrase II Deficiency|Guibaud-Vainsel Syndrome|Marble Brain Disease|OPTB3

    a rare, autosomal recessive inherited disorder caused by mutation in the ca2 gene. it is characterized by osteopetrosis, renal tubular acidosis, and cerebral calcifications. it results in growth failure, mental retardation, and fractures.

  • Other Specified Diabetes Mellitus with Ketoacidosis with Coma|Other specified diabetes mellitus with ketoacidosis with coma

    evidence of other specified diabetes mellitus with ketoacidosis with coma not specified elsewhere.

  • Other Specified Diabetes Mellitus with Ketoacidosis without Coma|Other specified diabetes mellitus with ketoacidosis without coma

    evidence of other specified diabetes mellitus with ketoacidosis without coma not specified elsewhere.

  • Proximal Renal Tubular Acidosis|Type II Renal Tubular Acidosis

    impairment in renal proximal tubule bicarbonate reabsorption that results in a hypokalemic hyperchloremic metabolic acidosis, which is most commonly associated with renal fanconi syndrome.

  • Renal Tubular Acidosis Associated With Deafness

    renal tubular acidosis associated with sensorineural hearing loss, and which is typically associated with recessive mutations.

  • Renal Tubular Acidosis|renal tubular acidosis

    the inability of the kidneys to maintain acid-base homeostasis.

  • Respiratory Acidosis

    acid base imbalance resulting from an accumulation of carbon dioxide secondary to hypoventilation.

  • Respiratory Acidosis|Hypercapnic Acidosis

    a condition in which the blood ph is less than normal, secondary to impaired gas exchange.

  • Type 1 Diabetes Mellitus with Ketoacidosis with Coma|Type 1 diabetes mellitus with ketoacidosis with coma

    evidence of type 1 diabetes mellitus with ketoacidosis with coma.

  • Type 1 Diabetes Mellitus with Ketoacidosis without Coma|Type 1 diabetes mellitus with ketoacidosis without coma

    evidence of type 1 diabetes mellitus with ketoacidosis without coma.

  • Type 2 Diabetes Mellitus with Ketoacidosis with Coma|Type 2 diabetes mellitus with ketoacidosis with coma

    evidence of type 2 diabetes mellitus with ketoacidosis with coma.

  • Type 2 Diabetes Mellitus with Ketoacidosis without Coma|Type 2 diabetes mellitus with ketoacidosis without coma

    evidence of type 2 diabetes mellitus with ketoacidosis without coma.

  • Type I Renal Tubular Acidosis

    impairment in renal collecting tubule acid secretion that results in a hypokalemic hyperchloremic metabolic acidosis.

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement E87.29 replaces the following previously assigned code(s):

  • E87.2 - Acidosis
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E87.29Overview

Is E87.29 (Acidosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other acidosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E87.29 group to?

When other acidosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.