2026 ICD-10-CM Diagnosis Code E83.52Hypercalcemia

ICD-10-CM Codes›E00–E89›E70-E88›E83

ICD-10-CM E83.52
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E83.52 is a billable ICD-10-CM diagnosis code for hypercalcemia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 640 through 641. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E83.52
Billable Status
Yes — Valid for Submission
Code Describes
Hypercalcemia
Short Description
Hypercalcemia
Same as the full description in the CMS dataset.
Parent Code
E83.5
Disorders of calcium metabolism

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE83Disorders of mineral metabolism
This CodeE83.52Hypercalcemia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired hypocalciuric hypercalcemia
  • Acute milk alkali syndrome
  • Autosomal recessive hypophosphatemic bone disease
  • Autosomal recessive infantile hypercalcemia
  • Chronic milk alkali syndrome
  • Dementia due to hypercalcemia
  • Dementia due to metabolic abnormality
  • Familial hypocalciuric hypercalcemia
  • Familial hypomagnesemia hypercalciuria nephrocalcinosis with severe ocular involvement
  • Familial hypomagnesemia-hypercalciuria
  • Familial idiopathic hypercalciuria
  • Familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis
  • Familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis without severe ocular involvement
  • Hereditary hypophosphatemic rickets with hypercalciuria
  • Humoral hypercalcemia of malignancy
  • Hypercalcemia
  • Hypercalcemia associated with chronic dialysis
  • Hypercalcemia caused by a drug
  • Hypercalcemia caused by lithium
  • Hypercalcemia caused by thiazide and/or retinol
  • Hypercalcemia due to chronic kidney disease
  • Hypercalcemia due to granulomatous disease
  • Hypercalcemia due to hyperthyroidism
  • Hypercalcemia due to hypervitaminosis D
  • Hypercalcemia due to immobilization
  • Hypercalcemia due to sarcoidosis
  • Hypercalcemia due to tuberculosis
  • Hypocalciuric hypercalcemia
  • Idiopathic hypercalcemia
  • Idiopathic hypercalcemia of infancy
  • Idiopathic infantile hypercalcemia - mild form
  • Infantile hypercalcemia
  • Milk alkali syndrome
  • Myopathy co-occurrent and due to hypercalcemia
  • Nutritional disorder due to calcium-phosphorus imbalance
  • Secondary hypercalcemia
  • Serum calcium level above reference range
  • Subacute milk alkali syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Familial hypocalciuric hypercalcemia

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Burnett's syndrome
    • Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
      • in (due to)
        • hypercalcemia
    • Dementia(degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)
      • in (due to)
        • hypercalcemia
          • with behavioral disturbance
    • Disorder(of)
      • metabolism NOS
        • calcium
          • hypercalcemia
    • Hypercalcemia, hypocalciuric, familial
    • Milk-alkali disease or syndrome
    • Syndrome
      • Burnett's (milk-alkali)
    • Syndrome
      • milk-alkali

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hypercalcemia

    abnormally high level of calcium in the blood.

  • Williams Syndrome

    a disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, including the elastin gene. clinical manifestations include supravalvular aortic stenosis; mental retardation; elfin facies; impaired visuospatial constructive abilities; and transient hypercalcemia in infancy. the condition affects both sexes, with onset at birth or in early infancy.

  • Nephrocalcinosis

    deposition of calcium in the renal parenchyma, resulting from high levels of calcium in the blood and/or urine.

Patient EducationClinical

Calcium

Calcium is a mineral, a nutrient that you need (in small amounts) to keep your body healthy. You have more calcium in your body than any other mineral.

The full article covers:

  • What is calcium and why do I need it?
  • How do I get calcium?
  • How much calcium do I need?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E83.52 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
275.42 Hypercalcemia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E83.52Overview

Is E83.52 (Disorders of calcium metabolism) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hypercalcemia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E83.52 group to?

When hypercalcemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 640, 641, with relative weights from 0.7782 to 1.3356 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E83.52?

Under the General Equivalence Mappings, hypercalcemia converts to ICD-9-CM 275.42 (hypercalcemia). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.