2027 ICD-10-CM Diagnosis Code E83.111Hemochromatosis due to repeated red blood cell transfusions

ICD-10-CM Codes›E00–E89›E70-E88›E83

ICD-10-CM E83.111
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E83.111 is a billable ICD-10-CM diagnosis code for hemochromatosis due to repeated red blood cell transfusions. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 642. Coders also document this condition as hemochromatosis following repeated red blood cell transfusion. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E83.111
Billable Status
Yes — Valid for Submission
Code Describes
Hemochromatosis due to repeated red blood cell transfusions
Short Description
Hemochromatosis due to repeated red blood cell transfusions
Same as the full description in the CMS dataset.
Parent Code
Hemochromatosis

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE83Disorders of mineral metabolism
This CodeE83.111Hemochromatosis due to repeated red blood cell transfusions

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hemochromatosis following repeated red blood cell transfusion
  • Secondary hemochromatosis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E83.111: its own notes plus those printed at E83.11, E83.1, E83, block E70-E88, and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Iron overload due to repeated red blood cell transfusions
  • Transfusion (red blood cell) associated hemochromatosis

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From E83.11 Hemochromatosis applies to 4 codes
  • GALD (P78.84)
  • Gestational alloimmune liver disease (P78.84)
  • Neonatal hemochromatosis (P78.84)
From E83.1 Disorders of iron metabolism applies to 6 codes
From E83 Disorders of mineral metabolism applies to 31 codes
  • dietary mineral deficiency (E58-E61)
  • parathyroid disorders (E20-E21)
  • vitamin D deficiency (E55.-)
From Block E70-E88 Metabolic disorders applies to 286 codes
  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block E70-E88 Metabolic disorders applies to 286 codes
  • Ehlers-Danlos syndromes (Q79.6-)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E83.111, its category, or a range that includes it.

Excludes1 3

These codes carry an Excludes1 note naming E83.111: they are not reported together with it, unless the two conditions are unrelated.

  • E61 Deficiency of other nutrient elements
    disorders of mineral metabolism (E83.-) names E83.-, which includes this code
  • P78.84 Gestational alloimmune liver disease
    hemochromatosis (E83.11-) names E83.11-, which includes this code
  • R79.0 Abnormal level of blood mineral
    disorders of mineral metabolism (E83.-) names E83.-, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming E83.111: its condition is not part of those codes, and both may be reported when the patient has both.

  • T80 Complications following infusion, transfusion and therapeutic injection
    transfusion (red blood cell) associated hemochromatosis (E83.111)
  • Block K70-K77 Diseases of liver
    hemochromatosis (E83.11-) names E83.11-, which includes this code

Code First 2

These codes say to code first a condition named in the note, and E83.111 is one of the conditions named.

  • J84.03 Idiopathic pulmonary hemosiderosis
    disorders of iron metabolism (E83.1-) names E83.1-, which includes this code
  • M14.8 Arthropathies in other specified diseases classified elsewhere
    hemochromatosis (E83.11-) names E83.11-, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hemochromatosis

    a disorder of iron metabolism characterized by a triad of hemosiderosis; liver cirrhosis; and diabetes mellitus. it is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (jablonski's dictionary of syndromes & eponymic diseases, 2d ed)

Patient EducationClinical

Hemochromatosis

Hemochromatosis is a disease in which too much iron builds up in your body. Your body needs iron but too much of it is toxic. If you have hemochromatosis, you absorb more iron than you need. Your body has no natural way to get rid of the extra iron. It stores it in body tissues, especially the liver, heart, and pancreas.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E83.111 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
275.02 Hemochromatos-rbc trans
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E83.111Overview

What is the ICD-10 code for hemochromatosis due to repeated red blood cell transfusions?

The ICD-10-CM code for hemochromatosis due to repeated red blood cell transfusions is E83.111 (sometimes written as E83111). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is E83.111 (Hemochromatosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hemochromatosis due to repeated red blood cell transfusions on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does E83.111 group to?

When hemochromatosis due to repeated red blood cell transfusions is the principal diagnosis on an inpatient stay, it groups to MS-DRG 642 (inborn and Other Disorders of Metabolism), which carries a relative weight of 1.3226. Higher weights mean higher Medicare reimbursement.

Can E83.111 be reported with P78.84?

Not as a rule. The Excludes1 note at E83.11, which applies to E83.111, lists "GALD (P78.84)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of E83.111?

Under the General Equivalence Mappings, hemochromatosis due to repeated red blood cell transfusions converts to ICD-9-CM 275.02 (hemochromatos-rbc trans). The mapping is a direct match.