2026 ICD-10-CM Diagnosis Code E77.8Other disorders of glycoprotein metabolism

ICD-10-CM CodesE00–E89E70-E88E77

ICD-10-CM E77.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E77.8 is a billable ICD-10-CM diagnosis code for other disorders of glycoprotein metabolism. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E77.8
Billable Status
Yes — Valid for Submission
Code Describes
Other disorders of glycoprotein metabolism
Short Description
Other disorders of glycoprotein metabolism
Same as the full description in the CMS dataset.
Parent Code
Disorders of glycoprotein metabolism

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE77Disorders of glycoprotein metabolism
This CodeE77.8Other disorders of glycoprotein metabolism

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Alpha-2-antitrypsin deficiency
  • Alpha-N-acetylgalactosaminidase deficiency
  • Alpha-N-acetylgalactosaminidase deficiency type 1
  • Alpha-N-acetylgalactosaminidase deficiency type 2
  • Alpha-N-acetylgalactosaminidase deficiency type 3
  • CAD-CDG - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase congenital disorder of glycosylation
  • Carbohydrate deficient glycoprotein syndrome type 1m
  • Carbohydrate deficient glycoprotein syndrome type 1o
  • Carbohydrate deficient glycoprotein syndrome type 2a
  • Carbohydrate deficient glycoprotein syndrome type 2d
  • Carbohydrate deficient glycoprotein syndrome type 2k
  • Carbohydrate deficient glycoprotein syndrome type II due to MAN1B1 deficiency
  • Carbohydrate-deficient glycoprotein syndrome
  • Carbohydrate-deficient glycoprotein syndrome type I
  • Carbohydrate-deficient glycoprotein syndrome type II
  • Carbohydrate-deficient glycoprotein syndrome type III
  • COG2-related congenital disorder of glycosylation
  • COG6-CGD - component of oligomeric golgi complex 6-congenital disorder of glycosylation
  • Congenital disorder of glycosylation type Ia
  • Disorder of sialic acid metabolism
  • Edema due to hypoproteinemia
  • Glycoprotein storage disorder
  • Hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency
  • Mannosephosphate isomerase congenital disorder of glycosylation
  • NGLY1-congenital disorder of deglycosylation
  • Normocytic anemia
  • Pulmonary edema due to hypoproteinemia
  • TMEM199 congenital disorder of glycosylation

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disorder(of)
      • glycoprotein metabolism
        • specified NEC
    • Disorder(of)
      • metabolism NOS
        • glycoprotein
          • specified NEC
    • Hypoproteinemia
    • Syndrome
      • carbohydrate-deficient glycoprotein (CDGS)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Normocytic Anemia

    anemia in which the red blood cell volume is normal.

Patient EducationClinical

Carbohydrate Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system (enzymes) break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E77.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
272.7 Lipidoses
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E77.8Overview

Is E77.8 (Disorders of glycoprotein metabolism) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other disorders of glycoprotein metabolism on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of E77.8?

Under the General Equivalence Mappings, other disorders of glycoprotein metabolism converts to ICD-9-CM 272.7 (lipidoses). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.