2027 ICD-10-CM Diagnosis Code D69.59Other secondary thrombocytopenia

ICD-10-CM Codes›D50–D89›D65-D69›D69

ICD-10-CM D69.59
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D69.59 is a billable ICD-10-CM diagnosis code for other secondary thrombocytopenia. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793, 813. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coagulation and hemorrhagic disorders.

Code Identity

ICD-10-CM Code
D69.59
Billable Status
Yes — Valid for Submission
Code Describes
Other secondary thrombocytopenia
Short Description
Other secondary thrombocytopenia
Same as the full description in the CMS dataset.
Parent Code
Secondary thrombocytopenia

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD65-D69Coagulation defects, purpura and other hemorrhagic conditions
CategoryD69Purpura and other hemorrhagic conditions
This CodeD69.59Other secondary thrombocytopenia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Alloimmune platelet transfusion refractoriness
  • Alloimmune thrombocytopenia
  • Allosensitization
  • Benign gestational thrombocytopenia
  • Dilutional thrombocytopenia
  • Drug-induced immune thrombocytopenia
  • Drug-induced purpura
  • Infection-associated purpura
  • Platelet alloimmunization
  • Poisoning caused by alcohol
  • Post infectious thrombocytopenic purpura
  • Primary ITP
  • Purpura due to drug-induced capillary damage
  • Purpura due to drug-induced coagulation abnormality
  • Secondary autoimmune thrombocytopenia
  • Secondary thrombocytopenia
  • Thrombocytopenia caused by alcohol
  • Thrombocytopenia caused by drugs
  • Thrombocytopenia caused by ionizing radiation
  • Thrombocytopenia co-occurrent and due to alcoholism
  • Thrombocytopenia due to blood loss
  • Thrombocytopenia due to COVID-19
  • Thrombocytopenia due to extracorporeal circulation
  • Thrombocytopenia due to hypersplenism
  • Thrombocytopenia due to hypothermia
  • Thrombocytopenia due to massive blood transfusion
  • Thrombocytopenia due to non-immune destruction
  • Thrombocytopenia due to sequestration
  • Thrombocytopenia with AIDS
  • Thrombocytopenic purpura associated with metabolic disorder
  • Thrombocytopenic purpura due to platelet consumption
  • Thrombosis with thrombocytopenia syndrome following vaccination
  • Uremic thrombocytopenia
  • VITT - vaccine-induced immune thrombotic thrombocytopenia

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D69.59: its own notes plus those printed at D69.5, D69, and Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From D69.5 Secondary thrombocytopenia applies to 2 codes
  • heparin induced thrombocytopenia (HIT) (D75.82-)
  • transient thrombocytopenia of newborn (P61.0)
From D69 Purpura and other hemorrhagic conditions applies to 13 codes
  • benign hypergammaglobulinemic purpura (D89.0)
  • cryoglobulinemic purpura (D89.1)
  • essential (hemorrhagic) thrombocythemia (D47.3)
  • hemorrhagic thrombocythemia (D47.3)
  • purpura fulminans (D65)
  • thrombotic thrombocytopenic purpura (M31.19)
  • Waldenström hypergammaglobulinemic purpura (D89.0)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D69.59, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming D69.59: they are not reported together with it, unless the two conditions are unrelated.

  • R23.3 Spontaneous ecchymoses
    purpura (D69.-) names D69.-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming D69.59: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block R70-R79 Abnormal findings on examination of blood, without diagnosis
    abnormalities of platelets and thrombocytes (D69.-) names D69.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD006
Coagulation and hemorrhagic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Platelet Disorders

Platelets, also known as thrombocytes, are blood cells. They form in your bone marrow, a sponge-like tissue in your bones. Platelets play a major role in blood clotting. Normally, when one of your blood vessels is injured, you start to bleed.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D69.59 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
287.49 Sec thrombocytpenia NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D69.59Overview

What is the ICD-10 code for other secondary thrombocytopenia?

The ICD-10-CM code for other secondary thrombocytopenia is D69.59 (sometimes written as D6959). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is D69.59 (Secondary thrombocytopenia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other secondary thrombocytopenia on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D69.59 group to?

When other secondary thrombocytopenia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 813, with relative weights from 1.5279 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D69.59 be reported with a code from D75.82?

Not as a rule. The Excludes1 note at D69.5, which applies to D69.59, lists "heparin induced thrombocytopenia (HIT) (D75.82-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of D69.59?

Under the General Equivalence Mappings, other secondary thrombocytopenia converts to ICD-9-CM 287.49 (sec thrombocytpenia NEC). The mapping is a direct match.