2027 ICD-10-CM Diagnosis Code D60.9Acquired pure red cell aplasia, unspecified
ICD-10-CM Codes›D50–D89›D60-D64›D60
- Billable — Valid for Submission
- MCC — Major Complication or Comorbidity
- Risk Adjusts — HCC 109
- Chronic Condition
D60.9 is a billable ICD-10-CM diagnosis code for acquired pure red cell aplasia, unspecified. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 808 through 810. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 110 closely related codes. Coders also document this condition as acquired red cell aplasia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Aplastic anemia.
For Medicare Advantage risk adjustment, D60.9 maps to CMS-HCC Category 109 (Acquired Hemolytic, Aplastic, and Sideroblastic Anemias) under the V28 model, adding a risk factor of about 1.144 for a community, non-dual, aged beneficiary in payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D60.9 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acquired red cell aplasia
- Adult pure red cell aplasia
- Antibody mediated acquired pure red cell aplasia caused by erythropoiesis stimulating agent
- Decreased erythroid precursor production
- Osteonecrosis due to acquired red cell aplasia
- Pure red cell aplasia
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to D60.9: its own notes plus those printed at D60 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- red cell aplasia (acquired) (adult) (with thymoma)
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name D60.9, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) D64.9
red cell (pure) D60.9
pure red cell D60.9
Aplasia See Also: Agenesis;
red cell (with thymoma) D60.9
acquired D60.9
due to drugs D60.9
adult D60.9
due to drugs D60.9
due to drugs D60.9
Erythroblastopenia See Also: Aplasia, red cell; D60.9
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Acquired Pure Red Cell Aplasia
a disease characterized by normocytic, normochromic anemia, low hematocrit, reticulocytopenia and selective erythroid hypoplasia. it can occur as a chronic or acute form; the former is predominantly seen in adults and the latter in children. pathogenesis involves immune dysfunction with antibodies directed against erythroid precursor cells or erythropoietin, or due to t-cell mediated suppression of erythropoiesis.
Patient EducationClinical
Anemia
If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D60.9 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D60.9Overview
What is the ICD-10 code for acquired pure red cell aplasia, unspecified?
The ICD-10-CM code for acquired pure red cell aplasia, unspecified is D60.9 (sometimes written as D609). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is D60.9 (Acquired pure red cell aplasia [erythroblastopenia]) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report acquired pure red cell aplasia, unspecified on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does D60.9 group to?
When acquired pure red cell aplasia, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 808, 809, 810, with relative weights from 1.0749 to 2.1706 depending on complications. Higher weights mean higher Medicare reimbursement.
Is D60.9 a CC or MCC?
CMS lists D60.9 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 110 closely related codes in its exclusion list.
Can D60.9 be reported with D61.01?
Not as a rule. The Excludes1 note at D60, which applies to D60.9, lists "congenital red cell aplasia (D61.01)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What HCC is D60.9?
D60.9 (acquired pure red cell aplasia, unspecified) maps to CMS-HCC Category 109 (Acquired Hemolytic, Aplastic, and Sideroblastic Anemias), commonly written as HCC 109, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 46 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 96.
Does D60.9 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, D60.9 adds a risk adjustment factor of about 1.144 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.529 to 1.815 depending on the payment segment). HCC 109 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 109 category page.
