2026 ICD-10-CM Diagnosis Code C92.00Acute myeloblastic leukemia, not having achieved remission

ICD-10-CM Codes›C00–D49›C81-C96›C92

ICD-10-CM C92.00
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C92.00 is a billable ICD-10-CM diagnosis code for acute myeloblastic leukemia, not having achieved remission. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 820 through 822, 834 through 839. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Leukemia - acute myeloid leukemia (AML).

Code Identity

ICD-10-CM Code
C92.00
Billable Status
Yes — Valid for Submission
Code Describes
Acute myeloblastic leukemia, not having achieved remission
Short Description
Acute myeloblastic leukemia, not having achieved remission
Same as the full description in the CMS dataset.
Parent Code
C92.0
Acute myeloblastic leukemia

Code Classification

ChapterC00–D49Neoplasms
SectionC81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue
CategoryC92Myeloid leukemia
This CodeC92.00Acute myeloblastic leukemia, not having achieved remission

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute myeloid leukemia and myelodysplastic syndrome related to alkylating agent
  • Acute myeloid leukemia and myelodysplastic syndrome related to radiation
  • Acute myeloid leukemia and myelodysplastic syndrome related to topoisomerase type 2 inhibitor
  • Acute myeloid leukemia with CBFB::MYH11 fusion
  • Acute myeloid leukemia with CEBPA somatic mutations
  • Acute myeloid leukemia with inv; RPN1-EVI1
  • Acute myeloid leukemia with NPM1 somatic mutation
  • Acute myeloid leukemia with t RUNX1-RUNX1T1
  • Acute myeloid leukemia, disease
  • Acute myeloid leukemia, minimal differentiation, FAB M0
  • Disorder of bone marrow caused by ionizing radiation
  • Hematologic complication of procedure
  • Inherited acute myeloid leukemia
  • Refractory acute myeloid leukemia
  • Therapy related acute myeloid leukemia due to and following administration of antineoplastic agent
  • Therapy-related myelodysplastic syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Acute myeloblastic leukemia with failed remission
  • Acute myeloblastic leukemia NOS

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO060
Leukemia - acute myeloid leukemia (AML)
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Acute Myeloid Leukemia

Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:

The full article covers:

  • What is leukemia?
  • What is acute myeloid leukemia (AML)?
  • What causes acute myeloid leukemia (AML)?
  • Who is at risk for acute myeloid leukemia (AML)?
  • What are the symptoms of acute myeloid leukemia (AML)?
  • How is acute myeloid leukemia (AML) diagnosed?
  • What are the treatments for acute myeloid leukemia (AML)?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C92.00 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
205.00 Ac myl leuk wo achv rmsn
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C92.00Overview

Is C92.00 (Acute myeloblastic leukemia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report acute myeloblastic leukemia, not having achieved remission on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C92.00 group to?

When acute myeloblastic leukemia, not having achieved remission is the principal diagnosis on an inpatient stay, it groups to MS-DRG 820, 821, 822, 834, 835, 836, 837, 838, 839, with relative weights from 1.2040 to 5.8648 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C92.00?

Under the General Equivalence Mappings, acute myeloblastic leukemia, not having achieved remission converts to ICD-9-CM 205.00 (ac myl leuk wo achv rmsn). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.