2027 ICD-10-CM Diagnosis Code N16Renal tubulo-interstitial disorders in diseases classified elsewhere
ICD-10-CM Codes›N00–N99›N10-N16›N16
- Billable — Valid for Submission
- Not Chronic
N16 is a billable ICD-10-CM diagnosis code for renal tubulo-interstitial disorders in diseases classified elsewhere. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 698 through 700. The code is a manifestation code that cannot be reported as the principal diagnosis. Coders also document this condition as acute nephritis due to another disorder. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nephritis; nephrosis; renal sclerosis.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for N16.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acute nephritis due to another disorder
- Acute tubulointerstitial nephritis
- Acute tubulo-interstitial nephritis due to immunological disorder
- Immunoglobulin G4 related kidney disease
- Pyelitis
- Pyelitis associated with another disorder
- Pyelonephritis associated with another disorder
- Renal tubulo-interstitial disorder due to cystinosis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to N16: its own notes plus those printed at block N10-N16 and Chapter 14. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Pyelonephritis
- Tubulo-interstitial nephritis
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
- pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
- pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
- pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
- pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
- pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
- pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
- pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
- renal tubular degeneration in diabetes (E08-E13 with .29)
- syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)
- pyeloureteritis cystica (N28.85)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Code First
The underlying condition named in the note is sequenced before this code.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name N16, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming N16: they are not reported together with it, unless the two conditions are unrelated.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Kidney Diseases
You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters.
Read the full article at MedlinePlus
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Convert N16 to ICD-9-CMHistory
Code HistoryHistory
Questions About N16Overview
What is the ICD-10 code for renal tubulo-interstitial disorders in diseases classified elsewhere?
The ICD-10-CM code for renal tubulo-interstitial disorders in diseases classified elsewhere is N16. It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is N16 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report renal tubulo-interstitial disorders in diseases classified elsewhere on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does N16 group to?
On inpatient claims, renal tubulo-interstitial disorders in diseases classified elsewhere maps to MS-DRG 699, 698, 700, with relative weights from 0.6740 to 1.6400 depending on complications. Higher weights mean higher Medicare reimbursement.
Can N16 be a principal diagnosis?
No. This is a manifestation code: renal tubulo-interstitial disorders in diseases classified elsewhere describes the manifestation of an underlying disease rather than the disease itself, so the underlying condition is sequenced first.
Can N16 be reported with A36.84?
Not as a rule. The Excludes1 note on N16 lists "diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
