ICD-10-CM Code C92.40

Acute promyelocytic leukemia, not having achieved remission

Version 2021 Billable Code

Valid for Submission

C92.40 is a billable code used to specify a medical diagnosis of acute promyelocytic leukemia, not having achieved remission. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code C92.40 might also be used to specify conditions or terms like acute promyelocytic leukemia - hypogranular variant or acute promyelocytic leukemia, fab m3 or acute promyelocytic leukemia, fab m3 or differentiation syndrome due to and following chemotherapy co-occurrent with acute promyelocytic leukemia or hypergranular promyelocytic leukemia.

ICD-10:C92.40
Short Description:Acute promyelocytic leukemia, not having achieved remission
Long Description:Acute promyelocytic leukemia, not having achieved remission

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code C92.40:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Acute promyelocytic leukemia with failed remission
  • Acute promyelocytic leukemia NOS

Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acute promyelocytic leukemia - hypogranular variant
  • Acute promyelocytic leukemia, FAB M3
  • Acute promyelocytic leukemia, FAB M3
  • Differentiation syndrome due to and following chemotherapy co-occurrent with acute promyelocytic leukemia
  • Hypergranular promyelocytic leukemia

Diagnostic Related Groups

The ICD-10 code C92.40 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2021.

  • 820 - LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH MCC
  • 821 - LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITH CC
  • 822 - LYMPHOMA AND LEUKEMIA WITH MAJOR O.R. PROCEDURES WITHOUT CC/MCC

Convert C92.40 to ICD-9

  • 205.00 - Ac myl leuk wo achv rmsn (Approximate Flag)

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
      • Myeloid leukemia (C92)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Acute Myeloid Leukemia

Also called: AML, ANLL, Acute myelogenous leukemia

Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In acute myeloid leukemia (AML), there are too many of a specific type of white blood cell called a myeloblast.

AML is the most common type of acute leukemia in adults. This type of cancer usually gets worse quickly if it is not treated. Possible risk factors include smoking, previous chemotherapy treatment, and exposure to radiation.

Symptoms of AML include:

  • Fever
  • Shortness of breath
  • Easy bruising or bleeding
  • Bleeding under the skin
  • Weakness or feeling tired
  • Weight loss or loss of appetite

Tests that examine the blood and bone marrow diagnose AML. Treatments include chemotherapy, other drugs, radiation therapy, stem cell transplants, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Once the leukemia is in remission, you need additional treatment to make sure that it does not come back.

NIH: National Cancer Institute

  • Acute myelogenous leukemia (AML) -- children (Medical Encyclopedia)
  • Acute myeloid leukemia (Medical Encyclopedia)
  • After chemotherapy - discharge (Medical Encyclopedia)
  • Bone marrow transplant (Medical Encyclopedia)
  • Bone marrow transplant - discharge (Medical Encyclopedia)

[Learn More]

Acute promyelocytic leukemia Acute promyelocytic leukemia is a form of acute myeloid leukemia, a cancer of the blood-forming tissue (bone marrow). In normal bone marrow, hematopoietic stem cells produce red blood cells (erythrocytes) that carry oxygen, white blood cells (leukocytes) that protect the body from infection, and platelets (thrombocytes) that are involved in blood clotting. In acute promyelocytic leukemia, immature white blood cells called promyelocytes accumulate in the bone marrow. The overgrowth of promyelocytes leads to a shortage of normal white and red blood cells and platelets in the body, which causes many of the signs and symptoms of the condition.People with acute promyelocytic leukemia are especially susceptible to developing bruises, small red dots under the skin (petechiae), nosebleeds, bleeding from the gums, blood in the urine (hematuria), or excessive menstrual bleeding. The abnormal bleeding and bruising occur in part because of the low number of platelets in the blood (thrombocytopenia) and also because the cancerous cells release substances that cause excessive bleeding.The low number of red blood cells (anemia) can cause people with acute promyelocytic leukemia to have pale skin (pallor) or excessive tiredness (fatigue). In addition, affected individuals may heal slowly from injuries or have frequent infections due to the loss of normal white blood cells that fight infection. Furthermore, the leukemic cells can spread to the bones and joints, which may cause pain in those areas. Other general signs and symptoms may occur as well, such as fever, loss of appetite, and weight loss.Acute promyelocytic leukemia is most often diagnosed around age 40, although it can be diagnosed at any age.
[Learn More]