2022 ICD-10-CM Code E16.3

Increased secretion of glucagon

Version 2021

Valid for Submission

ICD-10:E16.3
Short Description:Increased secretion of glucagon
Long Description:Increased secretion of glucagon

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)
      • Other disorders of pancreatic internal secretion (E16)

E16.3 is a billable diagnosis code used to specify a medical diagnosis of increased secretion of glucagon. The code E16.3 is valid during the fiscal year 2022 from October 01, 2021 through September 30, 2022 for the submission of HIPAA-covered transactions.

The ICD-10-CM code E16.3 might also be used to specify conditions or terms like abnormality of secretion of glucagon, excessive glucagon secretion, glucagon resistance, hyperplasia of islet alpha cells with glucagon excess, islet cell hyperplasia , non-diabetic disorder of endocrine pancreas, etc.

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E16.3:


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E16.3 are found in the index:

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Convert E16.3 to ICD-9 Code

Information for Patients


Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include

The pancreas also plays a role in diabetes. In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked them. In type 2 diabetes, the pancreas loses the ability to secrete enough insulin in response to meals.


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Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)