ICD-10-CM Code D35.2

Benign neoplasm of pituitary gland

Version 2020 Billable Code Neoplasm Benign

Valid for Submission

D35.2 is a billable code used to specify a medical diagnosis of benign neoplasm of pituitary gland. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D35.2 might also be used to specify conditions or terms like acth-dependent cushing's syndrome, benign neoplasm of craniopharyngeal duct, benign neoplasm of pituitary gland, benign neoplasm of pituitary gland and craniopharyngeal duct, corticotroph adenoma, familial isolated pituitary adenoma, etc

The following anatomical sites found in the Table of Neoplasms apply to this code given the correct histological behavior: craniobuccal pouch ; fossa (of) pituitary ; hypophysis ; intrasellar ; pituitary (body) (fossa) (gland) (lobe) ; Rathke's pouch ; sella turcica ; etc

Short Description:Benign neoplasm of pituitary gland
Long Description:Benign neoplasm of pituitary gland

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D35.2 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • ACTH-dependent Cushing's syndrome
  • Benign neoplasm of craniopharyngeal duct
  • Benign neoplasm of pituitary gland
  • Benign neoplasm of pituitary gland and craniopharyngeal duct
  • Corticotroph adenoma
  • Familial isolated pituitary adenoma
  • Functioning pituitary neoplasm
  • Functioning pituitary neoplasm
  • Functioning pituitary neoplasm
  • Functioning pituitary neoplasm
  • Functionless pituitary adenoma
  • Functionless pituitary neoplasm
  • Gonadotroph adenoma
  • Granular cell tumor
  • Granular cell tumor of neurohypophysis
  • Hamartoma of brain
  • Hamartoma of hypothalamus
  • Hamartoma of pituitary and hypothalamus
  • Hypercortisolism due to pituitary adenoma
  • Invasive pituitary adenoma
  • Macroprolactinoma
  • Mass of posterior lobe of pituitary
  • Microprolactinoma
  • Mixed-functioning pituitary adenoma
  • Neoplasm of craniopharyngeal duct
  • Pituitary adenoma
  • Pituitary adenoma with extrasellar extension
  • Pituitary macroadenoma
  • Pituitary macroadenoma with extrasellar extension
  • Pituitary mesoadenoma
  • Pituitary microadenoma
  • Prolactinoma
  • Secondary hyperprolactinemia
  • Secondary hyperprolactinemia due to prolactin-secreting tumor
  • Somatomammotropinoma
  • Somatotroph adenoma
  • Suprasellar extension of pituitary adenoma
  • Thyrotoxicosis due to inappropriate TSH secretion
  • Thyrotoxicosis due to TSHoma
  • Thyrotroph adenoma
  • Thyrotropin overproduction

Diagnostic Related Groups

The ICD-10 code D35.2 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2020.


Convert D35.2 to ICD-9

  • 227.3 - Benign neo pituitary (Approximate Flag)

Code Classification

  • Neoplasms (C00–D48)
    • Benign neoplasms, except benign neuroendocrine tumors (D10-D36)
      • Benign neoplasm of other and unspecified endocrine glands (D35)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Table of Neoplasms

The code D35.2 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
CaInSitu Benign Uncertain
»craniobuccal pouch
»fossa (of)
»pituitary (body) (fossa) (gland) (lobe)
»Rathke's pouch
»sella turcica

Information for Patients

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Tumors are made up of extra cells. Normally, cells grow and divide to form new cells as your body needs them. When cells grow old, they die, and new cells take their place. Sometimes, this process goes wrong. New cells form when your body does not need them, and old cells do not die when they should. These extra cells can divide without stopping and may form tumor.

Treatment often involves surgery. Benign tumors usually don't grow back.

NIH: National Cancer Institute

[Learn More]

Pituitary Disorders

Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it makes hormones that affect growth and the functions of other glands in the body.

With pituitary disorders, you often have too much or too little of one of your hormones. Injuries can cause pituitary disorders, but the most common cause is a pituitary tumor.

[Learn More]