2026 ICD-10-CM Diagnosis Code R87.821Vaginal low risk human papillomavirus (HPV) DNA test positive

ICD-10-CM Codes›R00–R99›R83-R89›R87

ICD-10-CM R87.821
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R87.821 is a billable ICD-10-CM diagnosis code for vaginal low risk human papillomavirus (HPV) DNA test positive. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 742 through 743, 760 through 761. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as human papillomavirus deoxyribonucleic acid detected. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.

This medical diagnosis code is frequently used in OB/GYN medical specialties to designate conditions such abnormal female genital cytology.

Code Identity

ICD-10-CM Code
R87.821
Billable Status
Yes — Valid for Submission
Code Describes
Vaginal low risk human papillomavirus (HPV) DNA test positive
Short Description
Vaginal low risk HPV DNA test positive
Parent Code
R87.82
Low risk human papillomavirus (HPV) DNA test positive from female genital organs

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR83-R89Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
CategoryR87Abnormal findings in specimens from female genital organs
This CodeR87.821Vaginal low risk human papillomavirus (HPV) DNA test positive

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Human papillomavirus deoxyribonucleic acid detected
  • Low risk human papillomavirus deoxyribonucleic acid detected in specimen from vagina

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abnormal, abnormality, abnormalities
      • specimen
        • female genital organs (secretions) (smears)
          • cytology
            • vagina
              • human papillomavirus (HPV) DNA test
                • low risk positive
    • Findings, abnormal, inconclusive, without diagnosis
      • human papillomavirus (HPV) DNA test positive
        • vagina
          • low risk
    • Human
      • papillomavirus (HPV)
        • DNA test positive
          • low risk
            • vagina

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM017
Abnormal findings without diagnosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

HPV

Human papillomavirus (HPV) is a group of more than 200 related viruses. Some of them are spread through sexual contact. Most people have been exposed to HPV. Usually, your immune system controls HPV infections, and they go away on their own and don't cause any health problems, but some need treatment.

The full article covers:

  • What is HPV?
  • Who is at risk for HPV infections?
  • What are the symptoms of HPV infections?
  • How are HPV infections diagnosed?
  • What are the treatments for HPV infections?
  • Can HPV infections be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R87.821 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
795.19 Oth abn Pap smr vag/HPV
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R87.821Overview

Is R87.821 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report vaginal low risk human papillomavirus (HPV) DNA test positive on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R87.821 group to?

When vaginal low risk human papillomavirus (HPV) DNA test positive is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.5696 to 1.8348 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R87.821 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the vaginal low risk human papillomavirus (HPV) DNA test positive is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R87.821?

Under the General Equivalence Mappings, vaginal low risk human papillomavirus (HPV) DNA test positive converts to ICD-9-CM 795.19 (oth abn Pap smr vag/HPV). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.