Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)

ICD-10 codes R83 through R89 cover a range of abnormal findings detected in body fluids, tissues, and specimens from various organs, without a confirmed diagnosis. These codes are specifically used to document abnormal test results from fluids like cerebrospinal fluid, respiratory secretions, digestive and genital specimens, as well as other bodily tissues.

This code range includes detailed subcategories addressing abnormal enzyme, hormone, drug, immunological, microbiological, cytological, and histological findings in samples such as cerebrospinal fluid (R83), respiratory specimens (R84), digestive tract samples (R85), male genital specimens (R86), female genital specimens (R87), other body fluids (R88), and various other organs and tissues (R89). For example, terms like "CSF polymorphonuclear leukocytosis" correspond to abnormal cytological findings in cerebrospinal fluid under R83.6, while "Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)" relate to R87.610. These codes help clearly communicate specific abnormal lab findings; such as abnormal microbiological cultures, HPV DNA test results, or unusual immunological markers; when a diagnosis has not yet been established. This classification supports precise medical documentation and follow-up testing recommendations across many specialties, ensuring clarity when working with laboratory abnormalities identified in diverse clinical specimens.

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)

    • Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)

        • Abnormal findings in cerebrospinal fluid (R83)

        • R83 Abnormal findings in cerebrospinal fluid
        • R83.0 Abnormal level of enzymes in cerebrospinal fluid
        • R83.1 Abnormal level of hormones in cerebrospinal fluid
        • R83.2 Abnormal level of other drugs, medicaments and biological substances in cerebrospinal fluid
        • R83.3 Abnormal level of substances chiefly nonmedicinal as to source in cerebrospinal fluid
        • R83.4 Abnormal immunological findings in cerebrospinal fluid
        • R83.5 Abnormal microbiological findings in cerebrospinal fluid
        • R83.6 Abnormal cytological findings in cerebrospinal fluid
        • R83.8 Other abnormal findings in cerebrospinal fluid
        • R83.9 Unspecified abnormal finding in cerebrospinal fluid
        • Abnormal findings in specimens from respiratory organs and thorax (R84)

        • R84 Abnormal findings in specimens from respiratory organs and thorax
        • R84.0 Abnormal level of enzymes in specimens from respiratory organs and thorax
        • R84.1 Abnormal level of hormones in specimens from respiratory organs and thorax
        • R84.2 Abnormal level of other drugs, medicaments and biological substances in specimens from respiratory organs and thorax
        • R84.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from respiratory organs and thorax
        • R84.4 Abnormal immunological findings in specimens from respiratory organs and thorax
        • R84.5 Abnormal microbiological findings in specimens from respiratory organs and thorax
        • R84.6 Abnormal cytological findings in specimens from respiratory organs and thorax
        • R84.7 Abnormal histological findings in specimens from respiratory organs and thorax
        • R84.8 Other abnormal findings in specimens from respiratory organs and thorax
        • R84.9 Unspecified abnormal finding in specimens from respiratory organs and thorax
        • Abnormal findings in specimens from digestive organs and abdominal cavity (R85)

        • R85 Abnormal findings in specimens from digestive organs and abdominal cavity
        • R85.0 Abnormal level of enzymes in specimens from digestive organs and abdominal cavity
        • R85.1 Abnormal level of hormones in specimens from digestive organs and abdominal cavity
        • R85.2 Abnormal level of other drugs, medicaments and biological substances in specimens from digestive organs and abdominal cavity
        • R85.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from digestive organs and abdominal cavity
        • R85.4 Abnormal immunological findings in specimens from digestive organs and abdominal cavity
        • R85.5 Abnormal microbiological findings in specimens from digestive organs and abdominal cavity
        • R85.6 Abnormal cytological findings in specimens from digestive organs and abdominal cavity
        • R85.61 Abnormal cytologic smear of anus
        • R85.610 Atypical squamous cells of undetermined significance on cytologic smear of anus (ASC-US)
        • R85.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of anus (ASC-H)
        • R85.612 Low grade squamous intraepithelial lesion on cytologic smear of anus (LGSIL)
        • R85.613 High grade squamous intraepithelial lesion on cytologic smear of anus (HGSIL)
        • R85.614 Cytologic evidence of malignancy on smear of anus
        • R85.615 Unsatisfactory cytologic smear of anus
        • R85.616 Satisfactory anal smear but lacking transformation zone
        • R85.618 Other abnormal cytological findings on specimens from anus
        • R85.619 Unspecified abnormal cytological findings in specimens from anus
        • R85.69 Abnormal cytological findings in specimens from other digestive organs and abdominal cavity
        • R85.7 Abnormal histological findings in specimens from digestive organs and abdominal cavity
        • R85.8 Other abnormal findings in specimens from digestive organs and abdominal cavity
        • R85.81 Anal high risk human papillomavirus (HPV) DNA test positive
        • R85.82 Anal low risk human papillomavirus (HPV) DNA test positive
        • R85.89 Other abnormal findings in specimens from digestive organs and abdominal cavity
        • R85.9 Unspecified abnormal finding in specimens from digestive organs and abdominal cavity
        • Abnormal findings in specimens from male genital organs (R86)

        • R86 Abnormal findings in specimens from male genital organs
        • R86.0 Abnormal level of enzymes in specimens from male genital organs
        • R86.1 Abnormal level of hormones in specimens from male genital organs
        • R86.2 Abnormal level of other drugs, medicaments and biological substances in specimens from male genital organs
        • R86.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from male genital organs
        • R86.4 Abnormal immunological findings in specimens from male genital organs
        • R86.5 Abnormal microbiological findings in specimens from male genital organs
        • R86.6 Abnormal cytological findings in specimens from male genital organs
        • R86.7 Abnormal histological findings in specimens from male genital organs
        • R86.8 Other abnormal findings in specimens from male genital organs
        • R86.9 Unspecified abnormal finding in specimens from male genital organs
        • Abnormal findings in specimens from female genital organs (R87)

        • R87 Abnormal findings in specimens from female genital organs
        • R87.0 Abnormal level of enzymes in specimens from female genital organs
        • R87.1 Abnormal level of hormones in specimens from female genital organs
        • R87.2 Abnormal level of other drugs, medicaments and biological substances in specimens from female genital organs
        • R87.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from female genital organs
        • R87.4 Abnormal immunological findings in specimens from female genital organs
        • R87.5 Abnormal microbiological findings in specimens from female genital organs
        • R87.6 Abnormal cytological findings in specimens from female genital organs
        • R87.61 Abnormal cytological findings in specimens from cervix uteri
        • R87.610 Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US)
        • R87.611 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of cervix (ASC-H)
        • R87.612 Low grade squamous intraepithelial lesion on cytologic smear of cervix (LGSIL)
        • R87.613 High grade squamous intraepithelial lesion on cytologic smear of cervix (HGSIL)
        • R87.614 Cytologic evidence of malignancy on smear of cervix
        • R87.615 Unsatisfactory cytologic smear of cervix
        • R87.616 Satisfactory cervical smear but lacking transformation zone
        • R87.618 Other abnormal cytological findings on specimens from cervix uteri
        • R87.619 Unspecified abnormal cytological findings in specimens from cervix uteri
        • R87.62 Abnormal cytological findings in specimens from vagina
        • R87.620 Atypical squamous cells of undetermined significance on cytologic smear of vagina (ASC-US)
        • R87.621 Atypical squamous cells cannot exclude high grade squamous intraepithelial lesion on cytologic smear of vagina (ASC-H)
        • R87.622 Low grade squamous intraepithelial lesion on cytologic smear of vagina (LGSIL)
        • R87.623 High grade squamous intraepithelial lesion on cytologic smear of vagina (HGSIL)
        • R87.624 Cytologic evidence of malignancy on smear of vagina
        • R87.625 Unsatisfactory cytologic smear of vagina
        • R87.628 Other abnormal cytological findings on specimens from vagina
        • R87.629 Unspecified abnormal cytological findings in specimens from vagina
        • R87.69 Abnormal cytological findings in specimens from other female genital organs
        • R87.7 Abnormal histological findings in specimens from female genital organs
        • R87.8 Other abnormal findings in specimens from female genital organs
        • R87.81 High risk human papillomavirus (HPV) DNA test positive from female genital organs
        • R87.810 Cervical high risk human papillomavirus (HPV) DNA test positive
        • R87.811 Vaginal high risk human papillomavirus (HPV) DNA test positive
        • R87.82 Low risk human papillomavirus (HPV) DNA test positive from female genital organs
        • R87.820 Cervical low risk human papillomavirus (HPV) DNA test positive
        • R87.821 Vaginal low risk human papillomavirus (HPV) DNA test positive
        • R87.89 Other abnormal findings in specimens from female genital organs
        • R87.9 Unspecified abnormal finding in specimens from female genital organs
        • Abnormal findings in specimens from other organs, systems and tissues (R89)

        • R89 Abnormal findings in specimens from other organs, systems and tissues
        • R89.0 Abnormal level of enzymes in specimens from other organs, systems and tissues
        • R89.1 Abnormal level of hormones in specimens from other organs, systems and tissues
        • R89.2 Abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues
        • R89.3 Abnormal level of substances chiefly nonmedicinal as to source in specimens from other organs, systems and tissues
        • R89.4 Abnormal immunological findings in specimens from other organs, systems and tissues
        • R89.5 Abnormal microbiological findings in specimens from other organs, systems and tissues
        • R89.6 Abnormal cytological findings in specimens from other organs, systems and tissues
        • R89.7 Abnormal histological findings in specimens from other organs, systems and tissues
        • R89.8 Other abnormal findings in specimens from other organs, systems and tissues
        • R89.9 Unspecified abnormal finding in specimens from other organs, systems and tissues

Instructional Notations

Type 1 Excludes

A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • abnormal findings on antenatal screening of mother O28
  • diagnostic abnormal findings classified elsewhere - see Alphabetical Index

Type 2 Excludes

A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.

  • abnormal findings on examination of blood, without diagnosis R70 R79
  • abnormal findings on examination of urine, without diagnosis R80 R82
  • abnormal tumor markers R97