General symptoms and signs (R50-R69) ICD-10-CM
The R50–R69 section covers general symptoms and signs with 88 ICD-10-CM diagnosis codes, of which 68 are billable in fiscal year 2026. The section is organized into the 18 code ranges listed below.
Code Ranges in This Section 18 ranges · 88 codes
The info icon previews the code ranges inside each row and its instructional notations from the official Tabular List.
About the R50–R69 Code Range
ICD-10 codes R50-R69 cover general symptoms and signs not classified elsewhere, such as various fevers, headaches, pain, malaise, fatigue, syncope, convulsions, shock, hemorrhage, edema, and issues related to growth and feeding. These codes help document symptoms that are important for diagnosis but do not specify a particular disease.
The range includes codes for different types of fever like R50 (fever of unknown origin), drug-induced fever (R50.2), postprocedural fever (R50.82), and unspecified fever (R50.9). Headache codes (R51) cover unspecified headaches and orthostatic headaches. Pain codes (R52) describe unspecified pain across body regions. Malaise and fatigue codes (R53) capture general weakness, cancer-related fatigue, and chronic fatigue syndrome. Syncope codes (R55) address fainting and collapse. Convulsions (R56) include febrile and posttraumatic seizures. Shock codes (R57) cover cardiogenic, hypovolemic, and unspecified shock states. Hemorrhage codes (R58) document bleeding not categorized elsewhere. Edema codes (R60) cover localized and generalized swelling. Signs related to nutrition and development include anorexia (R63.0), feeding difficulties (R63.3), abnormal weight changes, and failure to thrive in childhood (R62.51) and adulthood (R62.7). Codes also describe symptoms linked with systemic inflammation and infection like sepsis (R65). This chapter aids in precise symptom documentation when a definitive diagnosis is not yet established.
Questions About This Page
How many codes are in the R50-R69 range?
The R50-R69 range contains 88 ICD-10-CM diagnosis codes in FY 2026. 68 of them are billable, and the rest are category headers that organize the section.
What conditions does R50-R69 cover?
The range covers general symptoms and signs. The code ranges listed above break it into groups of related conditions, and each one links to its own page with the full code list.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
