2026 ICD-10-CM Diagnosis Code R80Proteinuria

ICD-10-CM Codes›R00–R99›R80-R82›R80

ICD-10-CM R80
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R80 is a non-billable ICD-10-CM category code for proteinuria, so it cannot be submitted on claims. Use a more specific code from this category instead, such as R80.0, R80.1, R80.2, and R80.3. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established.

Code Identity

ICD-10-CM Code
R80
Billable Status
No — Non-Billable Category
Code Describes
Proteinuria
Chapter
R80-R82
Abnormal findings on examination of urine, without diagnosis

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR80-R82Abnormal findings on examination of urine, without diagnosis
CategoryR80Proteinuria
This CodeR80Proteinuria

Specific Coding for ProteinuriaOverview

Non-specific codes like R80 require more characters. Use one of these billable codes instead:

  • Use R80.0 for Isolated proteinuria

  • Use R80.1 for Persistent proteinuria, unspecified

  • Use R80.2 for Orthostatic proteinuria, unspecified

  • Use R80.3 for Bence Jones proteinuria

  • Use R80.8 for Other proteinuria

  • Use R80.9 for Proteinuria, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • gestational proteinuria O12.1

Clinical InformationClinical

  • Pre-Eclampsia

    a complication of pregnancy, characterized by a complex of symptoms including maternal hypertension and proteinuria with or without pathological edema. symptoms may range between mild and severe. pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

  • Proteinuria

    the presence of proteins in the urine, an indicator of kidney diseases.

  • Kidney Diseases

    pathological processes of the kidney or its component tissues.

  • Overflow Proteinuria|Overflow proteinuria

    a pathologic condition that occurs when the plasma concentration of low-molecular weight proteins exceeds the tubular capacity to reabsorb the filtered proteins.

  • Grade 1 Proteinuria, CTCAE|Grade 1 Proteinuria|Grade 1 Proteinuria

    1+ proteinuria; urinary protein > or = to uln-<1.0 g/24 hrs

  • Grade 2 Proteinuria, CTCAE|Grade 2 Proteinuria|Grade 2 Proteinuria

    adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; pediatric: urine p/c (protein/creatinine) ratio 0.5-1.9

  • Grade 3 Proteinuria, CTCAE|Grade 3 Proteinuria|Grade 3 Proteinuria

    adult: urinary protein >=3.5 g/24 hrs; 4+ proteinuria; pediatric: urine p/c (protein/creatinine) ratio >1.9

  • Maternal Proteinuria

    the presence of excessive protein, chiefly albumin but also globulin, in the urine of a pregnant woman.

  • Nephrotic Range Proteinuria

    in children, urine protein greater than or equal to 40mg/m^2/h; alternatively, greater than or equal to 0.25gm/mmol creatinine or 2gm/gm creatinine obtained from a first morning specimen.

  • Proteinuria

    the presence of abnormal amounts of protein in the urine.

  • Proteinuria, CTCAE 5.0|Proteinuria|Proteinuria

    a disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. it is predominantly albumin, but also globulin.

Patient EducationClinical

Urine and Urination

Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R80Overview

Is R80 (Proteinuria) a billable code?

No. This is a category header that groups the codes for proteinuria, and headers cannot be submitted on claims. Claims for proteinuria need a more specific code from this category, such as R80.0, R80.1, and R80.2.

Can R80 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the proteinuria is established, that condition takes the principal position instead.