Version 2024
No Valid Principal Dx

2024 ICD-10-CM Diagnosis Code R80


ICD-10-CM Code:
ICD-10 Code for:
Is Billable?
Not Valid for Submission
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Code Classification

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
    • Abnormal findings on examination of urine, without diagnosis
      • Proteinuria

R80 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of proteinuria. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Specific Coding Applicable to Proteinuria

Non-specific codes like R80 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for proteinuria:

  • Use R80.0 for Isolated proteinuria - BILLABLE CODE

  • Use R80.1 for Persistent proteinuria, unspecified - BILLABLE CODE

  • Use R80.2 for Orthostatic proteinuria, unspecified - BILLABLE CODE

  • Use R80.3 for Bence Jones proteinuria - BILLABLE CODE

  • Use R80.8 for Other proteinuria - BILLABLE CODE

  • Use R80.9 for Proteinuria, unspecified - BILLABLE CODE

Clinical Information

  • Pre-Eclampsia

    a complication of pregnancy, characterized by a complex of symptoms including maternal hypertension and proteinuria with or without pathological edema. symptoms may range between mild and severe. pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
  • Proteinuria

    the presence of proteins in the urine, an indicator of kidney diseases.
  • Kidney Diseases

    pathological processes of the kidney or its component tissues.
  • Grade 1 Proteinuria, CTCAE|Grade 1 Proteinuria|Grade 1 Proteinuria

    1+ proteinuria; urinary protein > or = to uln-<1.0 g/24 hrs
  • Grade 2 Proteinuria, CTCAE|Grade 2 Proteinuria|Grade 2 Proteinuria

    adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; pediatric: urine p/c (protein/creatinine) ratio 0.5-1.9
  • Grade 3 Proteinuria, CTCAE|Grade 3 Proteinuria|Grade 3 Proteinuria

    adult: urinary protein >=3.5 g/24 hrs; 4+ proteinuria; pediatric: urine p/c (protein/creatinine) ratio >1.9
  • Maternal Proteinuria

    the presence of excessive protein, chiefly albumin but also globulin, in the urine of a pregnant woman.
  • Nephrotic Range Proteinuria

    in children, urine protein greater than or equal to 40mg/m^2/h; alternatively, greater than or equal to 0.25gm/mmol creatinine or 2gm/gm creatinine obtained from a first morning specimen.
  • Proteinuria

    the presence of abnormal amounts of protein in the urine.
  • Proteinuria, CTCAE 5.0|Proteinuria|Proteinuria

    a disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. it is predominantly albumin, but also globulin.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • gestational proteinuria O12.1

Patient Education

Urine and Urination

Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate. It swells into a round shape when it is full and gets smaller when empty. If your urinary system is healthy, your bladder can hold up to 16 ounces (2 cups) of urine comfortably for 2 to 5 hours.

You may have problems with urination if you have:

  • Kidney failure
  • Urinary tract infections
  • An enlarged prostate
  • Bladder control problems like incontinence, overactive bladder, or interstitial cystitis
  • A blockage that prevents you from emptying your bladder

Some conditions may also cause you to have blood or protein in your urine. If you have a urinary problem, see your health care provider. Urinalysis and other urine tests can help to diagnose the problem. Treatment depends on the cause.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.