2026 ICD-10-CM Diagnosis Code Q81.2Epidermolysis bullosa dystrophica

ICD-10-CM Codes›Q00-Q99›Q80-Q89›Q81

ICD-10-CM Q81.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q81.2 is a billable ICD-10-CM diagnosis code for epidermolysis bullosa dystrophica. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 595 through 596. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified congenital anomalies.

Code Identity

ICD-10-CM Code
Q81.2
Billable Status
Yes — Valid for Submission
Code Describes
Epidermolysis bullosa dystrophica
Short Description
Epidermolysis bullosa dystrophica
Same as the full description in the CMS dataset.
Parent Code
Q81
Epidermolysis bullosa

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ80-Q89Other congenital malformations
CategoryQ81Epidermolysis bullosa
This CodeQ81.2Epidermolysis bullosa dystrophica

Present on Admission (POA)Billing

Q81.2 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acral dystrophic epidermolysis bullosa
  • Autosomal dominant generalized dystrophic epidermolysis bullosa
  • Centripetalis recessive dystrophic epidermolysis bullosa
  • Dominant dystrophic epidermolysis bullosa
  • Dominant dystrophic epidermolysis bullosa with absence of skin
  • Dominant dystrophic epidermolysis bullosa, albopapular type
  • Dystrophic epidermolysis bullosa
  • Dystrophic epidermolysis bullosa inverse type
  • Dystrophic epidermolysis bullosa nails only
  • Generalized dystrophic epidermolysis bullosa
  • Generalized recessive dystrophic epidermolysis bullosa mitis
  • Generalized recessive non-mutilating dystrophic epidermolysis bullosa
  • Localized dystrophic epidermolysis bullosa
  • Localized recessive dystrophic epidermolysis bullosa
  • Progressive recessive dystrophic epidermolysis bullosa
  • Recessive dystrophic epidermolysis bullosa
  • Recessive dystrophic epidermolysis bullosa non-Hallopeau Siemens type
  • Severe generalized recessive dystrophic epidermolysis bullosa

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Epidermolysis
      • bullosa (congenital)
        • dystrophica

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MAL010
Other specified and unspecified congenital anomalies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Epidermolysis Bullosa Dystrophica

    form of epidermolysis bullosa characterized by atrophy of blistered areas, severe scarring, and nail changes. it is most often present at birth or in early infancy and occurs in both autosomal dominant and recessive forms. all forms of dystrophic epidermolysis bullosa result from mutations in collagen type vii, a major component fibrils of basement membrane and epidermis.

  • Epidermolysis Bullosa with Congenital Localized Absence of Skin and Deformity of Nails|Autosomal Dominant Epidermolysis Bullosa Dystrophica, Bart Type|Bart Syndrome|Dominant dystrophic epidermolysis bullosa with absence of skin|Epidermolysis Bullosa Dystrophica, Bart Type

    a clinical variant of autosomal dominant epidermolysis bullosa dystrophica caused by mutation(s) in the col7a1 gene, encoding collagen alpha-1(vii) chain. a heterozygous 6007g-to-a transition in exon 73 results in a glycine-to-arginine substitution at position 2003 (g2003r) within the triple helical domain. this variant is characterized by the congenital absence of skin on the lower extremities, blistering of skin and mucous membranes, and the congenital absence or deformity of nails.

  • Epidermolysis Bullosa Dystrophica

    a genetic skin disorder caused by mutations in the type vii collagen gene (col7a1). it is characterized by the formation of blisters and scarring in the skin and mucous membranes.

  • Epidermolysis Bullosa Dystrophica, Autosomal Recessive|RDEB|Recessive Dystrophic Epidermolysis Bullosa

    an autosomal recessive allelic variant of epidermolysis bullosa dystrophica caused by mutation(s) in the col7a1 gene, encoding collagen alpha-1(vii) chain.

  • Epidermolysis Bullosa Dystrophica, Autosomal Dominant|Autosomal Dominant Generalized Dystrophic Epidermolysis Bullosa|DDEB

    an autosomal dominant allelic variant of epidermolysis bullosa dystrophica caused by heterozygous mutation(s) in the col7a1 gene, encoding collagen alpha-1(vii) chain.

  • Epidermolysis Bullosa Dystrophica, Autosomal Recessive|Autosomal Recessive Generalized Dystrophic Epidermolysis Bullosa|RDEB|Recessive Dystrophic Epidermolysis Bullosa

    an autosomal recessive allelic variant of epidermolysis bullosa dystrophica caused by mutation(s) in the col7a1 gene, encoding collagen alpha-1(vii) chain.

Patient EducationClinical

Skin Conditions

Your skin is your body's largest organ. It covers the entire outside of your body. There are many ways that your skin protects your body and helps keep you healthy. For example, it:

The full article covers:

  • What does your skin do?
  • What problems and conditions can affect your skin?
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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Q81.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
757.39 Skin anomaly NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Q81.2Overview

Is Q81.2 (Epidermolysis bullosa) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report epidermolysis bullosa dystrophica on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does Q81.2 group to?

When epidermolysis bullosa dystrophica is the principal diagnosis on an inpatient stay, it groups to MS-DRG 595, 596, with relative weights from 1.0825 to 2.1207 depending on complications. Higher weights mean higher Medicare reimbursement.

Is Q81.2 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for epidermolysis bullosa dystrophica on inpatient claims.

What is the ICD-9 equivalent of Q81.2?

Under the General Equivalence Mappings, epidermolysis bullosa dystrophica converts to ICD-9-CM 757.39 (skin anomaly NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.