2026 ICD-10-CM Diagnosis Code P61.5Transient neonatal neutropenia

ICD-10-CM CodesP00–P96P50-P61P61

ICD-10-CM P61.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P61.5 is a billable ICD-10-CM diagnosis code for transient neonatal neutropenia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 794. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 67 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemorrhagic and hematologic disorders of newborn.

Code Identity

ICD-10-CM Code
P61.5
Billable Status
Yes — Valid for Submission
Code Describes
Transient neonatal neutropenia
Short Description
Transient neonatal neutropenia
Same as the full description in the CMS dataset.
Parent Code
Other perinatal hematological disorders

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP61Other perinatal hematological disorders
This CodeP61.5Transient neonatal neutropenia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired neutropenia
  • Acquired neutropenia in newborn
  • Agranulocytosis
  • Alloimmune neonatal neutropenia
  • Febrile leukopenia
  • Febrile neutropenia
  • Immune neutropenia
  • Leukopenia
  • Maternal transfer neutropenia
  • Neutropenia
  • Neutropenia of the small for gestational age baby
  • Transient neonatal neutropenia
  • Transient neonatal neutropenia due to congenital viral infection
  • Transient neonatal neutropenia due to neonatal bacterial sepsis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • congenital neutropenia nontransient D70.0

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL011
Hemorrhagic and hematologic disorders of newborn
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Chemotherapy-Induced Febrile Neutropenia

    fever accompanied by a significant reduction in neutrophil count associated with chemotherapy.
  • Febrile Neutropenia

    fever accompanied by a significant reduction in the number of neutrophils.
  • Neutropenia

    a decrease in the number of neutrophils found in the blood.
  • Agranulocytosis

    a decrease in the number of granulocytes; (basophils; eosinophils; and neutrophils).
  • Feline Panleukopenia

    a highly contagious dna virus infection of the cat family, characterized by fever, enteritis and bone marrow changes. it is also called feline ataxia, feline agranulocytosis, feline infectious enteritis, cat fever, cat plague, and show fever. it is caused by feline panleukopenia virus or the closely related mink enteritis virus or canine parvovirus.
  • Leukopenia

    a decrease in the number of leukocytes in a blood sample below the normal range (leukocyte count less than 4000).
  • Neutrophils

    granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
  • Agranulocytosis

    a marked decrease in the number of mature granulocytes (most often neutrophils) in the peripheral blood.
  • Chemotherapy Related Agranulocytosis|Chemotherapy-Related Agranulocytosis

    agranulocytosis that occurs with chemotherapy.
  • Congenital Neutropenia|congenital neutropenia|genetic infantile agranulocytosis|infantile genetic agranulocytosis

    a rare congenital disorder characterized by mild or severe reduction of neutrophils in the peripheral blood and recurrent infantile infections.
  • Cyclic Neutropenia|CH|CN|Cyclic Agranulocytosis|Cyclic Hematopoiesis|Cyclic Hematopoiesis|Dysplasia, Myelocytic Periodic|Periodic Neutropenia|cyclic neutropenia|periodic neutropenia

    a hematologic disorder caused by a mutation in the elane (ela2) gene; clinical manifestations include recurrent neutropenia with resultant susceptibility to infection leading to fever.
  • Autoimmune Neutropenia|AIN|AIN

    a condition characterized by the autoantibody-induced destruction of neutrophils.
  • Immune Neutropenia

    neutropenia caused by immune destruction of mature neutrophils. it may be further categorized as autoimmune, alloimmune, drug-induced, or idiopathic immune neutropenia.

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P61.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
776.7 Neonatal neutropenia
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P61.5Overview

What is the ICD-10 code for transient neonatal neutropenia?

The ICD-10-CM code for transient neonatal neutropenia is P61.5 (sometimes written as P615). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is P61.5 (Other perinatal hematological disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report transient neonatal neutropenia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does P61.5 group to?

When transient neonatal neutropenia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 794 (neonate with Other Significant Problems), which carries a relative weight of 1.4759. Higher weights mean higher Medicare reimbursement.

Is P61.5 a CC or MCC?

CMS lists P61.5 as an MCC (major complication or comorbidity) for FY 2026. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 67 closely related codes in its exclusion list.

What is the ICD-9 equivalent of P61.5?

Under the General Equivalence Mappings, transient neonatal neutropenia converts to ICD-9-CM 776.7 (neonatal neutropenia). The mapping is a direct match.