2026 ICD-10-CM Diagnosis Code P59.3Neonatal jaundice from breast milk inhibitor

ICD-10-CM Codes›P00–P96›P50-P61›P59

ICD-10-CM P59.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

P59.3 is a billable ICD-10-CM diagnosis code for neonatal jaundice from breast milk inhibitor. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 795. Coders also document this condition as neonatal jaundice due to delayed conjugation. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic jaundice and perinatal jaundice.

Code Identity

ICD-10-CM Code
P59.3
Billable Status
Yes — Valid for Submission
Code Describes
Neonatal jaundice from breast milk inhibitor
Short Description
Neonatal jaundice from breast milk inhibitor
Same as the full description in the CMS dataset.
Parent Code
P59
Neonatal jaundice from other and unspecified causes

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP59Neonatal jaundice from other and unspecified causes
This CodeP59.3Neonatal jaundice from breast milk inhibitor

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Neonatal jaundice due to delayed conjugation
  • Neonatal jaundice due to delayed conjugation from breast milk inhibitor

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL007
Hemolytic jaundice and perinatal jaundice
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Jaundice

Jaundice causes your skin and the whites of your eyes to turn yellow. Too much bilirubin causes jaundice. Bilirubin is a yellow chemical in hemoglobin, the substance that carries oxygen in your red blood cells. As red blood cells break down, your body builds new cells to replace them. The old ones are processed by the liver.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P59.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
774.39 Delay conjugat jaund NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About P59.3Overview

What is the ICD-10 code for neonatal jaundice from breast milk inhibitor?

The ICD-10-CM code for neonatal jaundice from breast milk inhibitor is P59.3 (sometimes written as P593). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is P59.3 (Neonatal jaundice from other and unspecified causes) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neonatal jaundice from breast milk inhibitor on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does P59.3 group to?

When neonatal jaundice from breast milk inhibitor is the principal diagnosis on an inpatient stay, it groups to MS-DRG 795 (normal Newborn), which carries a relative weight of 0.1998. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of P59.3?

Under the General Equivalence Mappings, neonatal jaundice from breast milk inhibitor converts to ICD-9-CM 774.39 (delay conjugat jaund NEC). The mapping is approximate, so confirm the match fits the documentation.