2027 ICD-10-CM Diagnosis Code P59.29Neonatal jaundice from other hepatocellular damage

ICD-10-CM Codes›P00–P96›P50-P61›P59

ICD-10-CM P59.29
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

P59.29 is a billable ICD-10-CM diagnosis code for neonatal jaundice from other hepatocellular damage. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 35 closely related codes. Coders also document this condition as early neonatal jaundice due to hepatitis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic jaundice and perinatal jaundice.

Code Identity

ICD-10-CM Code
P59.29
Billable Status
Yes — Valid for Submission
Code Describes
Neonatal jaundice from other hepatocellular damage
Short Description
Neonatal jaundice from other hepatocellular damage
Same as the full description in the CMS dataset.
Parent Code
P59.2
Neonatal jaundice from other and unspecified hepatocellular damage

Code Classification

ChapterP00–P96Certain conditions originating in the perinatal period
SectionP50-P61Hemorrhagic and hematological disorders of newborn
CategoryP59Neonatal jaundice from other and unspecified causes
This CodeP59.29Neonatal jaundice from other hepatocellular damage

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Early neonatal jaundice due to hepatitis
  • Infectious neonatal hepatitis
  • Inflammatory disease of liver
  • Neonatal giant cell hepatitis
  • Neonatal hepatitis
  • Perinatal disorders of liver and/or biliary system
  • Perinatal hepatitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to P59.29: its own notes plus those printed at P59.2, P59, block P50-P61, and Chapter 16. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Neonatal giant cell hepatitis
  • Neonatal (idiopathic) hepatitis

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From P59.2 Neonatal jaundice from other and unspecified hepatocellular damage applies to 2 codes
  • congenital viral hepatitis (P35.3)
From P59 Neonatal jaundice from other and unspecified causes applies to 7 codes
  • jaundice due to inborn errors of metabolism (E70-E88)
  • kernicterus (P57.-)
From Block P50-P61 Hemorrhagic and hematological disorders of newborn applies to 67 codes
  • congenital stenosis and stricture of bile ducts (Q44.3)
  • Crigler-Najjar syndrome (E80.5)
  • Dubin-Johnson syndrome (E80.6)
  • Gilbert syndrome (E80.4)
  • hereditary hemolytic anemias (D55-D58)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • tetanus neonatorum (A33)

Notes

General instructions on how these codes are used.

From Chapter 16 (P00-P96) Certain conditions originating in the perinatal period applies to 463 codes
  • Codes from this chapter are for use on newborn records only, never on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name P59.29, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming P59.29: they are not reported together with it, unless the two conditions are unrelated.

  • K72 Hepatic failure, not elsewhere classified
    icterus of newborn (P55-P59) names P55-P59, which includes this code
  • R17 Unspecified jaundice
    neonatal jaundice (P55, P57-P59) names P57-P59, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming P59.29: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block R70-R79 Abnormal findings on examination of blood, without diagnosis
    hemorrhagic and hematological disorders of newborn (P50-P61) names P50-P61, which includes this code

Code Also 1

These codes say P59.29 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • K76.82 Hepatic encephalopathy
    icterus of newborn (P55-P59) names P55-P59, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR PNL007
Hemolytic jaundice and perinatal jaundice
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Jaundice

Jaundice causes your skin and the whites of your eyes to turn yellow. Too much bilirubin causes jaundice. Bilirubin is a yellow chemical in hemoglobin, the substance that carries oxygen in your red blood cells. As red blood cells break down, your body builds new cells to replace them. The old ones are processed by the liver.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert P59.29 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
774.4 Fetal/neonatal hepatitis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About P59.29Overview

What is the ICD-10 code for neonatal jaundice from other hepatocellular damage?

The ICD-10-CM code for neonatal jaundice from other hepatocellular damage is P59.29 (sometimes written as P5929). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is P59.29 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neonatal jaundice from other hepatocellular damage on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does P59.29 group to?

When neonatal jaundice from other hepatocellular damage is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, with relative weights from 4.1073 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is P59.29 a CC or MCC?

CMS lists P59.29 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 35 closely related codes in its exclusion list.

Can P59.29 be reported with P35.3?

Not as a rule. The Excludes1 note at P59.2, which applies to P59.29, lists "congenital viral hepatitis (P35.3)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).