2026 ICD-10-CM Diagnosis Code G93.41Metabolic encephalopathy

ICD-10-CM Codes›G00–G99›G89-G99›G93

ICD-10-CM G93.41
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

G93.41 is a billable ICD-10-CM diagnosis code for metabolic encephalopathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 974 through 976. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative).

Code Identity

ICD-10-CM Code
G93.41
Billable Status
Yes — Valid for Submission
Code Describes
Metabolic encephalopathy
Short Description
Metabolic encephalopathy
Same as the full description in the CMS dataset.
Parent Code
G93.4
Other and unspecified encephalopathy

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG89-G99Other disorders of the nervous system
CategoryG93Other disorders of brain
This CodeG93.41Metabolic encephalopathy

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • 3-Methylglutaconic aciduria type 4
  • Acute disorder of hemodialysis
  • Acute reversible leukoencephalopathy with increased urinary alpha-ketoglutarate
  • Atypical glycine encephalopathy
  • Childhood encephalopathy due to thiamine pyrophosphokinase deficiency
  • Complication of hemodialysis
  • Congenital microcephaly, severe encephalopathy, progressive cerebral atrophy syndrome
  • Deficiency of dioxygenase
  • Dialysis disequilibrium syndrome
  • Encephalopathy due to mitochondrial and peroxisomal fission defect
  • Encephalopathy due to sulfite oxidase deficiency
  • Encephalopathy with sepsis
  • Ethylmalonic encephalopathy
  • Ethylmalonic encephalopathy protein 1 deficiency
  • Glucose transporter protein type 1 deficiency syndrome
  • Hyperglycinemia
  • Hyponatremic encephalopathy
  • Inborn error of amino acid metabolism
  • Infantile glycine encephalopathy
  • ITPA-related lethal infantile neurological disorder with cataract and cardiac involvement
  • MEGDEL syndrome
  • Metabolic encephalopathy
  • Mitochondrial DNA depletion syndrome, hepatocerebral form due to DGUOK deficiency
  • Mitochondrial encephalomyopathy
  • Mitochondrial neurogastrointestinal encephalomyopathy syndrome
  • Myxedema encephalopathy
  • Non-ketotic hyperglycinemia
  • Progressive polyneuropathy with bilateral striatal necrosis
  • Recurrent metabolic encephalomyopathic crises, rhabdomyolysis, cardiac arrhythmia, intellectual disability syndrome
  • Secondary amyloid encephalopathy
  • Severe X-linked mitochondrial encephalomyopathy
  • Thiamine-responsive encephalopathy
  • TMEM70 related mitochondrial encephalo-cardio-myopathy
  • Urate encephalopathy
  • Uremic encephalopathy

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Septic encephalopathy

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Encephalopathy(acute)
      • metabolic
    • Encephalopathy(acute)
      • septic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Brain Diseases

Your brain is the control center of your body. It controls your thoughts, memory, speech, and movement. It regulates the function of many organs. It's part of your nervous system, which also includes your spinal cord and peripheral nerves. The nervous system sends signals between your brain and the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G93.41 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
348.31 Metabolic encephalopathy
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About G93.41Overview

Is G93.41 (Other and unspecified encephalopathy) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report metabolic encephalopathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does G93.41 group to?

When metabolic encephalopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 974, 975, 976, with relative weights from 0.8945 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of G93.41?

Under the General Equivalence Mappings, metabolic encephalopathy converts to ICD-9-CM 348.31 (metabolic encephalopathy). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.