R65.11 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

Version 2023
No Valid Principal Dx
ICD-10:R65.11
Short Description:SIRS of non-infectious origin w acute organ dysfunction
Long Description:Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
Status: Valid for Submission
Version:ICD-10-CM 2023
Code Classification:
  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)
    • General symptoms and signs (R50-R69)
      • Symp and signs specifically assoc w sys inflam and infct (R65)

R65.11 is a billable ICD-10 code used to specify a medical diagnosis of systemic inflammatory response syndrome (sirs) of non-infectious origin with acute organ dysfunction. The code is valid during the fiscal year 2023 from October 01, 2022 through September 30, 2023 for the submission of HIPAA-covered transactions.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

According to ICD-10-CM guidelines this code should not to be used as a principal diagnosis code when a related definitive diagnosis has been established.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to this diagnosis code:


Use Additional Code

Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

Index to Diseases and Injuries References

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for this diagnosis code are found in the injuries and diseases index:

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10 Code Edits are applicable to this code:

Convert to ICD-9 Code

Source ICD-10 CodeTarget ICD-9 Code
R65.11995.94 - SIRS-noninf w ac org dys

Code History