2026 ICD-10-CM Diagnosis Code G35.ARelapsing-remitting multiple sclerosis
G35.A is a billable ICD-10-CM diagnosis code for relapsing-remitting multiple sclerosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). Coders also document this condition as relapsing remitting multiple sclerosis.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Relapsing remitting multiple sclerosis
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Exclude1: demyelinating disease of central nervous system, unspecified G37.9
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Sclerosis, sclerotic
- multiple (brain stem) (cerebral) (disseminated) (generalized) (spinal cord)
- relapsing-remitting
Clinical InformationClinical
Multiple Sclerosis
an autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. the usual pattern is one of recurrent attacks followed by partial recovery (see multiple sclerosis, relapsing-remitting), but acute fulminating and chronic progressive forms (see multiple sclerosis, chronic progressive) also occur. (adams et al., principles of neurology, 6th ed, p903)Multiple Sclerosis, Chronic Progressive
a form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. if the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. when the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. the term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (from ann neurol 1994;36 suppl:s73-s79; adams et al., principles of neurology, 6th ed, pp903-914)Multiple Sclerosis, Relapsing-Remitting
the most common clinical variant of multiple sclerosis, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. common clinical manifestations include loss of visual (see optic neuritis), motor, sensory, or bladder function. acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (adams et al., principles of neurology, 6th ed, pp903-914)ABCA12 wt Allele|ABC12|ARCI4A|ARCI4B|ATP Binding Cassette Subfamily A Member 12 wt Allele|ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 Gene|ATP-Binding Cassette, Subfamily A, Member 12 Gene|DKFZP434G232|ICR2B|Ichthyosis Congenita II, Lamellar Ichthyosis B Gene|LI2
human abca12 wild-type allele is located in the vicinity of 2q35 and is approximately 207 kb in length. this allele, which encodes glucosylceramide transporter abca12 protein, plays a role in both the membrane localization of glucosylceramide and other lipids in lamellar granules and in cholesterol transport. mutation of the gene is associated with autosomal recessive congenital ichthyosis (arci) types 4a and 4b (harlequin).Lamellar Ichthyosis
a very rare, autosomal recessive inherited skin disorder present at birth. it is characterized by the presence of a transparent membrane encasing the newborn. this membrane sheds in about two weeks after birth to reveal generalized scaling and skin erythema.
Code History & ChangesHistory
New Code G35.A was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.
Replacement G35.A replaces the following previously assigned code(s):
- G35 - Multiple sclerosis
Questions About G35.AOverview
Is G35.A (Multiple sclerosis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report relapsing-remitting multiple sclerosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
