MS-DRG · FY 2026 v43.0

MS-DRG 58 – Multiple Sclerosis and Cerebellar Ataxia with MCC

A Medical DRG in MDC 01 (Diseases & Disorders of the Nervous System). Inpatient cases group to DRG 58 when the ICD-10-CM principal diagnosis is one of the 31 codes listed below and a secondary diagnosis on the major complication or comorbidity (MCC) list is present. Its FY 2026 relative weight is 1.7095 with a geometric mean length of stay of 4.6 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
1.7095
Relative Weight
4.6
Geometric Mean LOS (days)
6.3
Arithmetic Mean LOS (days)
31
Principal Diagnosis Codes

Severity family

DRG 58with MCCWeight 1.7095 · GMLOS 4.6 daysDRG 59with CCWeight 1.2409 · GMLOS 3.6 daysDRG 60without CC/MCCWeight 0.9198 · GMLOS 2.9 days
How a case is assigned to DRG 58

The grouper first assigns the case to MDC 01 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 58; with CC → 59; without CC/MCC → 60.

ICD-10-CM

Principal Diagnosis Codes 31 codes · 5 categories

31 of 31 shown
G11 Hereditary ataxia11 codes
  • G11.0 Congenital nonprogressive ataxia
  • G11.10 Early-onset cerebellar ataxia, unspecified
  • G11.11 Friedreich ataxia
  • G11.19 Other early-onset cerebellar ataxia
  • G11.2 Late-onset cerebellar ataxia
  • G11.3 Cerebellar ataxia with defective DNA repair
  • G11.4 Hereditary spastic paraplegia
  • G11.5 Hypomyelination - hypogonadotropic hypogonadism - hypodontia
  • G11.6 Leukodystrophy with vanishing white matter disease
  • G11.8 Other hereditary ataxias
  • G11.9 Hereditary ataxia, unspecified
G32 Other degenerative disorders of nervous system in diseases classified elsewhere1 code
  • G32.81 Cerebellar ataxia in diseases classified elsewhere
G35 Multiple sclerosis8 codes
  • G35.A Relapsing-remitting multiple sclerosis
  • G35.B0 Primary progressive multiple sclerosis, unspecified
  • G35.B1 Active primary progressive multiple sclerosis
  • G35.B2 Non-active primary progressive multiple sclerosis
  • G35.C0 Secondary progressive multiple sclerosis, unspecified
  • G35.C1 Active secondary progressive multiple sclerosis
  • G35.C2 Non-active secondary progressive multiple sclerosis
  • G35.D Multiple sclerosis, unspecified
G36 Other acute disseminated demyelination4 codes
  • G36.0 Neuromyelitis optica [Devic]
  • G36.1 Acute and subacute hemorrhagic leukoencephalitis [Hurst]
  • G36.8 Other specified acute disseminated demyelination
  • G36.9 Acute disseminated demyelination, unspecified
G37 Other demyelinating diseases of central nervous system7 codes
  • G37.0 Diffuse sclerosis of central nervous system
  • G37.1 Central demyelination of corpus callosum
  • G37.2 Central pontine myelinolysis
  • G37.5 Concentric sclerosis [Balo] of central nervous system
  • G37.81 Myelin oligodendrocyte glycoprotein antibody disease
  • G37.89 Other specified demyelinating diseases of central nervous system
  • G37.9 Demyelinating disease of central nervous system, unspecified
ICD-10-PCS

Procedure Codes

Procedure codes do not drive assignment for this DRG. DRG 58 is a Medical DRG, assigned from the principal diagnosis above.

Frequently Asked Questions

What is MS-DRG 58?

MS-DRG 58 (Multiple Sclerosis and Cerebellar Ataxia with MCC) is a medical DRG in MDC 01 (Diseases & Disorders of the Nervous System). Its FY 2026 relative weight is 1.7095 with a geometric mean length of stay of 4.6 days.

What is the difference between DRG 58, 59, 60?

All 3 share the same base category; the severity of secondary diagnoses separates them: 58 (with MCC), 59 (with CC), 60 (without CC/MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many diagnosis codes group to DRG 58?

31 ICD-10-CM principal diagnosis codes group to this DRG, spanning 5 three-character categories.

What is the relative weight of DRG 58?

The FY 2026 relative weight of this DRG is 1.7095, meaning reimbursement of roughly 1.71 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

← PreviousDRG 57 – Degenerative Nervous System Disorders without MCC
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.