2026 ICD-10-CM Diagnosis Code G35.C0

Secondary progressive multiple sclerosis, unspecified

ICD-10-CM Code:
G35.C0
ICD-10 Code for:
Secondary progressive multiple sclerosis, unspecified
Is Billable?
Yes - Valid for Submission
Code Navigator:

G35.C0 is a billable diagnosis code used to specify a medical diagnosis of secondary progressive multiple sclerosis, unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

Unspecified diagnosis codes like G35.C0 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Code Classification

  • Diseases of the nervous system
    G00–G99
    • Demyelinating diseases of the central nervous system
      G35-G37
      • Multiple sclerosis
        G35

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

  • Progressive multiple sclerosis
  • Secondary progressive multiple sclerosis

New 2026 ICD-10-CM Code

G35.C0 is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Index of External Cause of Injuries

References found for this diagnosis code in the External Cause of Injuries Index:

    • Sclerosis, sclerotic
      • multiple (brain stem) (cerebral) (disseminated) (generalized) (spinal cord)
        • progressive
          • secondary

Replacement Code

G35C0 replaces the following previously assigned ICD-10-CM code(s):

  • G35 - Multiple sclerosis

Code History

  • FY 2026 - Code Added, effective from 10/1/2025 through 9/30/2026