Multiple sclerosis (G35) ICD-10-CM
The G35 code range covers multiple sclerosis with 11 ICD-10-CM diagnosis codes. 8 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Codes in the G35 Range 11 codes · 8 billable
- G35 Multiple sclerosisNon-billable
- G35.A Relapsing-remitting multiple sclerosis
- G35.B Primary progressive multiple sclerosisNon-billable
- G35.B0 Primary progressive multiple sclerosis, unspecified
- G35.B1 Active primary progressive multiple sclerosis
- G35.B2 Non-active primary progressive multiple sclerosis
- G35.C Secondary progressive multiple sclerosisNon-billable
- G35.C0 Secondary progressive multiple sclerosis, unspecified
- G35.C1 Active secondary progressive multiple sclerosis
- G35.C2 Non-active secondary progressive multiple sclerosis
- G35.D Multiple sclerosis, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the G35 range.
Multiple Sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Multiple Sclerosis, Relapsing-Remitting
The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914)
About the G35 Code Range
Multiple sclerosis involves the immune system damaging nerve insulation in the central nervous system. It belongs to a group of diseases marked by this damage.
Within G35, the subdivisions separate relapsing-remitting G35.A, primary progressive G35.B, secondary progressive G35.C, and unspecified G35.D multiple sclerosis. Both progressive forms split further into active, non-active, and unspecified types.
FY 2027 changes: The FY 2027 ICD-10-CM update, effective October 1, 2026, deleted G35.
Questions About This Page
How many billable codes are in the G35 range?
Of the 11 codes in this range, 8 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the G35 range classify?
The range classifies multiple sclerosis. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
