Multiple sclerosis (G35) ICD-10-CM
The G35 code range covers multiple sclerosis with 11 ICD-10-CM diagnosis codes. 8 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the G35 Range 11 codes · 8 billable
- G35 Multiple sclerosisNon-billable
- G35.A Relapsing-remitting multiple sclerosis New
- G35.B Primary progressive multiple sclerosisNon-billable
- G35.B0 Primary progressive multiple sclerosis, unspecified New
- G35.B1 Active primary progressive multiple sclerosis New
- G35.B2 Non-active primary progressive multiple sclerosis New
- G35.C Secondary progressive multiple sclerosisNon-billable
- G35.C0 Secondary progressive multiple sclerosis, unspecified New
- G35.C1 Active secondary progressive multiple sclerosis New
- G35.C2 Non-active secondary progressive multiple sclerosis New
- G35.D Multiple sclerosis, unspecified New
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the G35 range.
Multiple Sclerosis
An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Multiple Sclerosis, Chronic Progressive
A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)
Multiple Sclerosis, Relapsing-Remitting
The most common clinical variant of MULTIPLE SCLEROSIS, characterized by recurrent acute exacerbations of neurologic dysfunction followed by partial or complete recovery. Common clinical manifestations include loss of visual (see OPTIC NEURITIS), motor, sensory, or bladder function. Acute episodes of demyelination may occur at any site in the central nervous system, and commonly involve the optic nerves, spinal cord, brain stem, and cerebellum. (Adams et al., Principles of Neurology, 6th ed, pp903-914)
About the G35 Code Range
The ICD-10 code G35 is specifically used to identify and classify multiple sclerosis (MS), a chronic neurological condition affecting the brain and spinal cord. This code covers all forms and related complications of MS.
Multiple sclerosis is often referred to by various names such as "pediatric multiple sclerosis," "optic neuritis due to demyelinating disease," or "chronic central neuropathic pain due to multiple sclerosis," all of which fall under the G35 code. It also includes different MS types like "primary progressive multiple sclerosis," "relapsing remitting multiple sclerosis," and "secondary progressive multiple sclerosis." The code helps healthcare professionals and coders document symptoms and complications like "myelitis," "autonomic disorder due to multiple sclerosis," and "cognitive impairment due to multiple sclerosis." Using ICD-10 code G35 ensures accurate recording and tracking of MS and its many manifestations, from optic neuritis and brainstem involvement to progressive neurological impairment. This code is essential for managing MS diagnosis, treatment planning, and reporting in clinical and administrative settings.
Questions About This Page
How many billable codes are in the G35 range?
Of the 11 codes in this range, 8 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the G35 range classify?
The range classifies multiple sclerosis. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
