Other demyelinating diseases of central nervous system (G37) ICD-10-CM

A rare, rapidly progressive variant of multiple sclerosis. Characteristic findings of alternating bands of demyelinated and myelinated white matter in concentric layers may be seen throughout the central nervous system.

Any condition in which there is degeneration of the myelin sheath that covers the nerves of the central nervous system.

A rare central nervous system demyelinating condition affecting children and young adults. Pathologic findings include a large, sharply defined, asymmetric focus of myelin destruction that may involve an entire lobe or cerebral hemisphere. The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy. Concentric sclerosis of Balo is differentiated from diffuse cerebral sclerosis of Schilder by the pathologic finding of alternating bands of destruction and preservation of myelin in concentric rings. Alpers' Syndrome refers to a heterogeneous group of diseases that feature progressive cerebral deterioration and liver disease. (From Adams et al., Principles of Neurology, 6th ed, p914; Dev Neurosci 1991;13(4-5):267-73)

A rare neurological disorder characterized initially by selective demyelination and necrosis of the corpus callosum. It is associated with chronic ethanol consumption or malnutrition, and depending on the acuity of presentation, signs and symptoms may include an altered mental state, motor disturbances, seizures, delirium and coma.

A disease in which serum antibodies are directed against MYELIN-OLIGODENDROCYTE GLYCOPROTEIN. MOGAD is typically associated with ACUTE DISSEMINATED ENCEPHALOMYELITIS; NEUROMYELITIS OPTICA; or TRANSVERSE MYELITIS.

A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)

Of the 11 codes in this range, 9 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.

The range classifies other demyelinating diseases of central nervous system. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.