2026 ICD-10-CM Diagnosis Code G35.C1

Active secondary progressive multiple sclerosis

ICD-10-CM Code:
G35.C1
ICD-10 Code for:
Active secondary progressive multiple sclerosis
Is Billable?
Yes - Valid for Submission
Code Navigator:

G35.C1 is a billable diagnosis code used to specify a medical diagnosis of active secondary progressive multiple sclerosis. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2025 through September 30, 2026.

Code Classification

  • Diseases of the nervous system
    G00–G99
    • Demyelinating diseases of the central nervous system
      G35-G37
      • Multiple sclerosis
        G35

New 2026 ICD-10-CM Code

G35.C1 is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Secondary progressive multiple sclerosis with evidence of inflammatory disease activity

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Index of External Cause of Injuries

References found for this diagnosis code in the External Cause of Injuries Index:

    • Sclerosis, sclerotic
      • multiple (brain stem) (cerebral) (disseminated) (generalized) (spinal cord)
        • progressive
          • secondary
            • with
              • evidence of inflammatory disease activity
    • Sclerosis, sclerotic
      • multiple (brain stem) (cerebral) (disseminated) (generalized) (spinal cord)
        • progressive
          • secondary
            • active

Replacement Code

G35C1 replaces the following previously assigned ICD-10-CM code(s):

  • G35 - Multiple sclerosis

Code History

  • FY 2026 - Code Added, effective from 10/1/2025 through 9/30/2026